Clinical trials: Vitamin D Deficiency, completed
Vitamin D Deficiency
Environmental Influences on Vitamin D Status
Vitamin D deficiency is a common problem. The principal source of vitamin D for humans is solar exposure, with cutaneous synthesis of vitamin D by photoconversion of 7-dehydrocholesterol in the skin to pre-vitamin D3.
- Trial name
- Alaska/Hawaii (NCT00780247)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Creighton University
Hypovitaminosis D
A Study on Oral Vitamin D Megadoses
The purpose of this study is to determine if infrequent administration of oral vitamin D megadoses is effective treatment to maintain serum 25-hydroxyvitamin D(3) above target levels of 50-75 nmol/L.
- Trial name
- NCT01067898
- Testing
- vitamin D3 (cholecalciferol), olive oil, calcium carbonate
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Chest Pain
Does Vitamin D Deficiency Associated With Hypercoagulability & Increased Thrombin Generation?
Cardiovascular disease is the most common cause of mortality and morbidity worldwide. Recently, a growing body of evidence has identified Vitamin D deficiency as a potential risk factor for cardiovascular disease.
- Trial name
- NCT01799655
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Benign Paroxismal Positional Vertigo
BPPV Recurrence After CRM With & Without Supplementation
Benign paroxysmal positional vertigo (BPPV) may frequently recur even after successful canalith repositioning maneuvers (CRMs). This study investigates whether the addition of vitamin K₂ to vitamin D₃ offers additional benefits…
- Trial name
- RR-BPPV-DK (NCT07861464)
- Testing
- Combined vitamin D₃ and K₂ supplementation, Vitamin D₃ alone, Canalith repositioning maneuver (CRM) alone
- Where
- Jordan
- Volunteers
- 404 people
- Sponsor
- University of Jordan
X-linked Hypophosphatemia (XLH)
Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age
A Phase 1/2, Open-label, Multicenter, Non-randomized Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Paediatric Patients from Birth to Less than 1 Year of Age with X-linked Hypophosphatemia…
- Trial name
- NCT04188964
- Testing
- Burosumab
- Where
- 9 sites in Austria, France and 4 more
- Volunteers
- 16 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Vitamin D Deficiency, Burns
Vitamin D Deficiency in Adults Following a Major Burn Injury
This is a single site double blind randomized controlled trial of replacing Vitamin D for Vitamin D-deficient burn patients at a current recommended dose (400 IU daily) versus a higher dose (4000 IU daily).
- Trial name
- NCT05084248
- Testing
- Ergocalciferol Capsules
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Texas Southwestern Medical Center
Ectopic Pregnancy, Vitamin D Deficiency
Vitamin D in Ectopic Pregnancies
According to recent evidences, vitamin D was found to have important roles in female reproductive system, both in physiological and also pathological mechanisms.
- Trial name
- NCT03894735
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Anemia, Hemodialysis Complication
Cholecalciferol Supplementation in Hemodialysis Patients
This is prospective single-blind randomized study, in Ain Shams University hospital) in Egypt, to assess the impact of Cholecalciferol on Anemia status in regular hemodialysis outpatients
- Conditions
- Anemia, Hemodialysis Complication, Vitamin D Deficiency
- Trial name
- NCT05922696
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Obesity
Duration of Vitamin D Stores After Prolonged Vitamin D Substitution
Ingested or skin produced vitamin D is either hydroxylated in the liver to 25-hydroxyvitamin D (25(OH)D), metabolized and excreted in the urine, or stored in adipose and other tissues.
- Trial name
- NCT01729013
- Where
- Norway
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Vitamin D Deficiency
Prevalence and Consequences of Vitamin D Deficiency in Pregnant Women in Switzerland
The purpose of this study is to determine the prevalence of vitamin D deficiency among the population of pregnant women receiving prenatal care and giving birth at the investigators' clinic.
- Trial name
- PCVDDPWS (NCT02904720)
- Where
- Switzerland
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hyperphosphatemia
The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients
Elevated phosphorus levels are a common problem in dialysis patients. However, it is associated with an increase in death and hospitalizations.
- Trial name
- NCT00316472
- Testing
- Niacinamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency, Gastrointestinal Diseases
Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Patients with fat malabsorption due to Crohn's disease, ulcerative colitis, or other causes including cystic fibrosis, among others, or who have undergone gastric bypass have increased incidence of vitamin D deficiency relative…
- Trial name
- NCT01910792
- Testing
- Sperti Lamp
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston University
Vitamin D Deficiency
Effect of Vitamin D3 and Omega-3FA on Estradiol
The effect of vitamin D3 and omega-3 Fatty acids on estradiol levels.
- Trial name
- NCT03333564
- Testing
- VD3, Omega3-FA, VD3 and Omega-3FA
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Deficiency, Vitamin D, Diabetes, Gestational
The Relation Between Vitamin D and Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with the onset or first recognition during pregnancy.
- Trial name
- NCT03665974
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
X-linked Hypophosphatemia
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH
This is phase 3b open-label, international, multicenter study to continue to monitor the long-term safety and efficacy of burosumab in adult patients with XLH that participated in previous clinical trials with burosumab…
- Trial name
- NCT03920072
- Testing
- Burosumab
- Where
- 10 sites in France, Ireland and 2 more
- Volunteers
- 35 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Type 1 Diabetes Mellitus
Prevalence of Vitamin D Deficiency in Type 1 Diabetes Mellitus and Effect of Supplementation on Insulin Requirements
Our objective is to demonstrate that providing supplemental vitamin D to children with new onset DM will significantly decrease the levels of HbA1c and insulin requirement by the following methods. 1.
- Trial name
- NCT01029392
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health East
Secondary Hyperparathyroidism, Chronic Kidney Disease
Study to Assess Patient Management Practices and Quality of Life With Paricalcitol Capsules in the Treatment of Secondary Hyperparathyroidism in Stage 3-5 Chronic Kidney Disease Patients Not Yet on Dialysis
Paricalcitol capsules (Zemplar®) received marketing authorization in Sweden in late 2007 for the prevention and treatment of secondary hyperparathyroidism in patients with Stage 3 \& 4 Chronic Kidney Disease (CKD).
- Trial name
- CAPITOL (NCT01265992)
- Where
- 10 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Pediatric Disorder, Vitamin D Deficiency
Retinal Changes in Vitamin D Deficiency
Retinal tissue parameters of pediatric patients with vitamin D deficiency will be evaluated in this prospective case-control study. The patients will be divided into 2 groups according to the vitamin D level.
- Conditions
- Pediatric Disorder, Vitamin D Deficiency, Retinal Disease, Choroidal Disease
- Trial name
- VDD (NCT04891211)
- Testing
- Vitamin D deficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Vitamin D Deficiency
Treatment of Vitamin D Insufficiency
The purpose of this study is to answer the following questions: Does vitamin D increase calcium absorption, bone mass and muscle mass and function in women past menopause who have mildly low vitamin D levels? Do these benefits…
- Trial name
- NCT00933244
- Testing
- High Dose Vitamin D3, Low Dose Vitamin D3
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Oxidative Stress, Inflammation
Vitamin D, Oxidative Stress and Inflammation in Hemodialysis
Vitamin D deficiency is now considered a global problem in general population, but it seemed to be more prominent in chronic kidney disease (CKD) patients, especially those on regular hemodialysis.
- Conditions
- Oxidative Stress, Inflammation, Vitamin D Deficiency
- Trial name
- NCT05460338
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams University