Clinical trials: Vitamin D Deficiency, completed
Vitamin D Deficiency
Nutritional Requirements for Vitamin D in Pregnant Women
Randomised, placebo-controlled dose-response intervention study with vitamin D3 in pregnant women.
- Trial name
- DMAT (NCT02506439)
- Testing
- 10 mcg Vitamin D3, 20 mcg Vitamin D3
- Where
- 2 sites in Ireland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University College Cork
Vitamin D Deficiency
Topical Delivery of Vitamin D3 as Vitamin D Supplementation
After obtaining the approval from the IRB of University of Dammam and informed consent from 550 healthy patients, with vitamin D deficiency and vitamin D insufficiency and deficiency were recruited.
- Trial name
- NCT02735200
- Testing
- Application of topical vitamin d3 (Top-D), Application of Aloe vera gel
- Where
- Saudi Arabia
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Healthy Subjects, Vitamin D Deficiency
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D.
- Trial name
- NCT00742235
- Testing
- ergocalciferol
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Vitamin D Deficiency
The D-BIICEP Study
Athletes and active individuals have been identified as an at-risk group for a low vitamin D status, specifically those residing in countries of higher latitude (such as the United Kingdom).
- Trial name
- D-BIICEP (NCT03253055)
- Testing
- DEXA, pQCT, Lifestyle Questionnaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Vitamin D Deficiency
Optimization of Blood Levels of 25(OH)-Vitamin D in African Americans
Two-thirds of the US population, particularly African Americans (AA), is at risk for inadequate or deficient 25-hydroxy-vitamin D (25(OH)VD).
- Trial name
- NCT04939792
- Testing
- Vitamin D, Vitamin D + L-cysteine, L-cysteine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Renal Osteodystrophy
Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD
The proposed 6 month pilot and feasibility randomized trial will evaluate LMMS as an anabolic stimulus to bone in 30 adults on maintenance hemodialysis.
- Trial name
- NCT00364234
- Testing
- Low magnitude mechanical stimuli
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hypovitaminosis D
Vitamin D, Blood Pressure, Lipids, Infection and Depression
There are numerous indications for a relation between low serum levels of 25(OH)D and blood pressure, lipid levels, frequency of infections and tendency towards depression.
- Trial name
- NCT00960232
- Testing
- Cholecalciferol
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Vitamin D Deficiency, Renal Failure Chronic Requiring Hemodialysis
Hemodialysis Vitamin D Pilot
Vitamin D is a prohormone obtained through diet, supplementation, or sun exposure. Once absorbed, this nutritional vitamin D undergoes a two-step reaction in the liver and in the kidney to become the active hormone, calcitriol.
- Trial name
- NCT01214928
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Vitamin D Deficiency
Rapid Normalization of Vitamin D Deficiency in PICU
Vitamin D plays an important role in calcium balance, heart and lung health, inflammation, infection prevention, and muscle strength.
- Trial name
- VITdALIZE-KIDS (NCT03742505)
- Testing
- Cholecalciferol
- Where
- 10 sites in Canada
- Volunteers
- 424 people
- Sponsor
- Children's Hospital of Eastern Ontario
Hypophosphatasia (HPP)
Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)
This clinical trial studies the safety, tolerability, and pharmacology of asfotase alfa when given to adults with HPP.
- Trial name
- NCT00739505
- Testing
- Asfotase Alfa
- Where
- 3 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Osteoporosis, Vitamin D Deficiency
Physiologic Interactions Between the Adrenal- and the Parathyroid Glands
To investigate possible physiologic interactions between the adrenal- and the parathyroid glands in patients with secondary hyperparathyroidism.
- Conditions
- Osteoporosis, Vitamin D Deficiency, Cardiovascular Disease
- Trial name
- AldOst (NCT02572960)
- Testing
- Valsartan, Cholecalciferol
- Where
- Denmark
- Volunteers
- 81 people
- Sponsor
- University of Aarhus
Hypocalcemia, Pseudohypoparathyroidism
Studies of States With Resistance to Vitamin D and Parathyroid Hormone
Patients with confirmed or suspected states with resistance to vitamin D or parathyroid hormone (PTH) will be admitted for diagnosis, treatment review with suggestions for modifications to the current or new treatment and for…
- Conditions
- Hypocalcemia, Pseudohypoparathyroidism, Osteomalacia, Rickets
- Trial name
- NCT00001242
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Rickets, Osteomalacia
Maternal and Infant Vitamin Status During the First Nine Months of Infant Life
In this study the investigators wanted to assess vitamin D status and possible consequences of low plasma 25-hydroxyvitamin D levels in a population of healthy mothers and their infants, in the community of Aarhus, Denmark.
- Conditions
- Rickets, Osteomalacia, Osteoporosis
- Trial name
- NCT02548520
- Testing
- Blood and breastmilk samples
- Where
- Denmark
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Menopause Related Conditions, Vitamin D Deficiency
Vitamin D and Microvascular Function in Postmenopausal Women
Many observational studies have demonstrated links between serum levels of 25-hydroxyvitamin D [25(OH)D] and cardiovascular risk (CVR) factors. Microvascular dysfunction relates not only to CVR but also to metabolic disease.
- Conditions
- Menopause Related Conditions, Vitamin D Deficiency, Cardiovascular Diseases
- Trial name
- NCT05408273
- Testing
- Blood samples and Microvascular function assessment evaluated through laser-Doppler flowmetry by the LASER speckle contrast analysis (LASCA) device
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Oral Lichen Planus, Vitamin D Deficiency
The Role of Vitamin D in Amelioration of Oral Lichen Planus and Its Effect on Salivary IFN-γ Level
The goal of this clinical trial is to compare between the use of vitamin D supplement in conjunction with systemic steroids versus the use of systemic steroids alone in the management of patients with symptomatic Oral Lichen…
- Trial name
- NCT06204796
- Testing
- vitamin D supplement was given as 60,000 IU weekly in conjunction with systemic prednisone, Systemic prednisone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Cystic Fibrosis, Vitamin D Deficiency
Cholecalciferol for Vitamin D in Adult Cystic Fibrosis (CF) Patients
The main aim of the research question to test the primary hypothesis of this study, namely, Does 12 weeks of an additional 5000 IU daily of cholecalciferol increase serum 25OHD levels in adults with Cystic Fibrosis (CF) who have…
- Trial name
- NCT00685971
- Testing
- 5000 IU of cholecalciferol
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Unity Health Toronto
Iron Deficiency Anemia, Infectious Diseases
Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants
The objective of the program is to examine the efficacy of 6 month home micronutrient supplementation in Bedouin and Jewish children on improvements in nutritional status including measures of iron, ferritin, zinc and folic acid…
- Conditions
- Iron Deficiency Anemia, Infectious Diseases, Undernutrition
- Trial name
- NCT00276198
- Testing
- Sprinkles, Ferripel-3, Vitamins A&D drops
- Where
- Israel
- Volunteers
- 771 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Vitamin D Deficiency
The 'Hidden' Biological Impact of Vitamin D Deficiency: a Biomarker Study; Part 2
The investigators major aims are to: determine the vitamin D status of a group of young, apparently healthy adults in Hong Kong; examine inter-relationships between vitamin D status and biomarkers of DNA damage and repair…
- Trial name
- NCT02451787
- Testing
- Vitamin D
- Where
- Hong Kong
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Vitamin D Deficiency, Cystic Fibrosis
Vitamin D and Microbiota in Cystic Fibrosis
The objective of this study is to assess the effects of a high-dose vitamin D3 on the composition of gut and lung microbiota in adolescents and adults with cystic fibrosis who are vitamin D deficient.
- Trial name
- NCT02589444
- Testing
- High-Dose Vitamin D3, Stool Sample, Sputum Sample
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Emory University
Secondary Hyperparathyroidism
Etelcalcetide to Treat Secondary Hyperparathyroidism in Hemodialysis Patients With Chronic Kidney Disease-Mineral and Bone Disorder
The purpose of this study is to evaluate the effect of thrice weekly intravenous (IV) administration of etelcalcetide in the treatment of secondary hyperparathyroidism (SHPT) in hemodialysis patients with chronic kidney…
- Trial name
- NCT01414114
- Testing
- Etelcalcetide
- Volunteers
- 37 people
- Sponsor
- KAI Pharmaceuticals