Clinical trials: Vitamin Deficiencies
Vitamin A Deficiency
Efficacy of Yellow Cassava to Improve Vitamin A Status of Kenyan School Children
The overall aim of the project is to provide proof-of-principle that biofortification of cassava with vitamin A is a viable strategy to improve vitamin A status of deficient populations.
- Trial name
- CASSAVITA (NCT01614483)
- Testing
- Yellow cassava, White cassava
- Where
- Kenya
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Essential Hypertension
Efficacy of Amlodipine-folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine
To evaluate the efficacy of Amlodipine-folic Acid Tablets on reduction of blood pressure and plasma homocystein.
- Trial name
- NCT01848873
- Testing
- Amlodipine, amlodipine-FA tablet, low dose group, amlodipine-FA tablet ,high dose group
- Where
- 16 sites in China
- Volunteers
- 756 people
- Sponsor
- Shenzhen Ausa Pharmed Co.,Ltd
Cholestatic Liver Disease, Chronic Liver Disease (CLD)
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
The goal of this clinical trial is to learn whether adding calcitriol to vitamin D2 can improve vitamin D deficiency in children with cholestasis and chronic liver disease.
- Conditions
- Cholestatic Liver Disease, Chronic Liver Disease (CLD), Vitamin D Deficiency, Children
- Trial name
- VITD-CHOL (NCT07670611)
- Testing
- Vitamin D2, Calcitriol
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Chulalongkorn University
Vitamin D Deficiency
Magnitude of Changes in 25 OH Vitamin D3 Levels After Vitamin D3 Supplementation
Vitamin D deficiency is common world wide. 25 OH vitamin D level is the best indicator of vitamin D status. The determination of the appropriate dose of vitamin D supplement is essential for management of vitamin D deficiency as…
- Trial name
- NCT01170507
- Testing
- vitamin D3 1000 IU orally daily for 5 months, vitamin D3 3000 IU orally daily for 5 months, vitamin D3 5000 IU orally daily for 5 months
- Where
- Saudi Arabia
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Crohn's Disease, Vitamin D Deficiency
Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency
Aims:Prospectively observe the effects of Caltrate supplementation on the chronic course of Crohn's disease patients, analyze whether the effect of Caltrate on CD patients is affected by factors such as disease site, disease…
- Conditions
- Crohn's Disease, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04276636
- Testing
- Caltrate Pill
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Coronavirus Disease 2019 (COVID-19)
Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency
In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019
- Trial name
- COVIT-D (NCT04403932)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
Chronic Kidney Diseases, Deficiency, Vitamin D
Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney Disease
This study investigates the effect of vitamin D deficiency on drug metabolism and transport in patients with chronic kidney disease (CKD) and in healthy controls.
- Trial name
- NCT02360644
- Testing
- Cholecalciferol
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Benign Paroxysmal Positional Vertigo (BPPV)
Association Between Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency .
Association between Benign Paroxysmal Positional Vertigo and Vitamin D deficiency
- Trial name
- NCT07491965
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Sohag University
Pediatric Fractures, Hypovitaminosis D
Bone Outcomes, Obesity, Sunlight, and Trauma in Children
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and…
- Conditions
- Pediatric Fractures, Hypovitaminosis D, Obesity and Overweight
- Trial name
- BOOST (NCT07143552)
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Autism, Autism Spectrum Disorder
Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach
New research suggests that about 1 in 8 children may be diagnosed with an autism spectrum disorder (ASD) in the United States. This could be due to several reasons which remain unknown.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related
- Trial name
- NCT05453708
- Testing
- Survey
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Walden University
Obesity, Morbid, Homocystine; Metabolic Disorder
Homocysteine After Laparoscopic Roux-enY Gastric Bypass
Changes in homocysteine values after bariatric surgery remain controversially discussed. This is the first comprehensive summary to depict timeline changes in homocysteine levels following laparoscopic roux-en-Y gastric bypass.
- Conditions
- Obesity, Morbid, Homocystine; Metabolic Disorder, Bariatric Surgery Candidate, Folate Deficiency
- Trial name
- NCT03489538
- Testing
- laparoscopic long limb roux-en-Y gastric bypass
- Where
- Austria
- Volunteers
- 708 people
- Sponsor
- Medical University of Vienna
Vitamin D Deficiency
A Study to Assess the Effectiveness of an Investigational Drug in Elderly Subjects With Low Vitamin D Levels (0822A-009)
This study will assess the effectiveness of an investigational drug in elderly subjects with low vitamin D levels.
- Trial name
- NCT00242476
- Testing
- MK0822A
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy Subjects, Vitamin D Deficiency
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D.
- Trial name
- NCT00742235
- Testing
- ergocalciferol
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Protein Malnutrition, Vitamin Deficiency
Evaluation of Protein Intake and Micronutrient Supplementation After Bariatric Surgery
Obesity is a chronic disease in which accumulation of excess body fat can result in impaired health. In cases of severe obesity, weight loss surgery can be necessary as a treatment.
- Conditions
- Protein Malnutrition, Vitamin Deficiency, Mineral Deficiency, Trace Element Deficiency
- Trial name
- BOP (NCT04587076)
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- University Medicine Greifswald
Vitamin D Deficiency, Nephrolithiasis
The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium
The investigators hypothesize that a 3 month course of vitamin D supplementation to treat 25(OH)D deficiency in stone formers with high levels of 24-hour urinary calcium will not increase urinary calcium excretion by greater than…
- Trial name
- NCT00948740
- Testing
- vitamin D (ergocalciferol)
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Periodontal Disease, Vitamin D Deficiency
Periodontal and Cardiometabolic Responses to Vitamin D Intervention in African Americans With Periodontal Disease
Poor vitamin D status is very common in African Americans. Periodontitis (gum disease) are shown to be related to theincreased risk of cardiometabolic diseases.
- Trial name
- GumD (NCT02337257)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augusta University
Thiamine Deficiency
Further Development and Assessment of Tools to Measure Risk Factors for and Treatment of Thiamine Deficiency Disorders
Thiamine deficiency, including the most severe form infantile beriberi, is a public health concern across South and Southeast Asia, where monotonous diets rely on thiamine-poor white rice.
- Trial name
- NCT05390086
- Testing
- Standard of care
- Where
- 2 sites in Laos
- Volunteers
- 42 people
- Sponsor
- University of California, Davis
Osteopenia, Renal Osteodystrophy
Osteopenia and Renal Osteodystrophy: Evaluation and Management
The purpose of this study is to demonstrate whether pamidronate will preserve or increase bone mass in patients with adynamic bone disease, caused by low bone turnover.
- Trial name
- NCT00108394
- Testing
- pamidronate
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Vitamin D Deficiency
Intervention Study of Vitamin D Supplementation to Prevent Cardiovascular Disease
This is a 9 months, randomized, single center, open-label, parallel-group study to compare the efficacy and safety parameters of vitamin D supplementation in vitamin D deficiency subjects in China.
- Trial name
- NCT03339427
- Testing
- vitamin D, control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
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