Clinical trials: Vitamin Deficiencies
Vitamin D Deficiency
Comparison of 25-hydroxy Vitamin D Level in Caucasian Women Receiving Vitamin D Supplementation and Not Receiving Supplementation: a Randomized Controlled Trial.
The objective of this study is to assess whether vitamin D supplements are sufficient to increase females who are deficient or borderline deficient in vitamin D levels to normal levels.
- Trial name
- NCT00882505
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Primary Hyperparathyroidism, Hypercalcemia
Primary Hyperparathyroidism (PHPT): Early Effect of Vitamin D
Primary hyperparathyroidism (PHPT) is a common disease that occurs in 1 in 10,000 people every year. In the presence of this condition, the parathyroid glands produce excessive amounts of parathyroid hormone (PTH), which…
- Conditions
- Primary Hyperparathyroidism, Hypercalcemia, Vitamin D Deficiency, Osteoporosis
- Trial name
- NCT01329666
- Testing
- Vitamin D3
- Where
- United States
- Sponsor
- Columbia University
Crohn's Disease (CD), Ulcerative Colitis (UC)
Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis D
This study aims to evaluate the effect of vitamin D3 supplementation on disease activity and quality of life in IBD patients deficient in vitamin D, and also help determine the optimal dose of vitamin D3 for them.
- Trial name
- NCT01877577
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Vitamin D Deficiency, Pregnancy
Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome
The VitDTracking study focuses on the relevance of maternal vitamin D levels and their association with prematurity, aiming to improve maternal and child health outcomes, particularly by reducing avoidable preterm births.
- Trial name
- VitDTracking (NCT06292195)
- Testing
- Exposure
- Where
- 3 sites in Portugal
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Évora
Hypophosphatemic Rickets, X-Linked Dominant
Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets
This study will measure the effect of cinacalcet (Sensipar) on parathyroid hormone (PTH) secretion in children and adolescents with hypophosphatemic rickets (XLH).
- Trial name
- NCT00195936
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's Mercy Hospital Kansas City
Nursing Home, Vitamin D Deficiency
SUN LIGHT EXPOSURE AND VITAMIN D LEVEL IN NURSING HOME
Objective: The aim of the present study was to determine the effect of nursing interventions and sunlight exposure to reach optimum vitamin D levels by individuals living in nursing homes on vitamin D levels.
- Trial name
- NCT04469257
- Testing
- Sunbathing
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tokat Gaziosmanpasa University
Endothelial Dysfunction, Hyperhomocysteinemia
Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
The present study aims at investigating the effects of the oral supplementation with creatine on the systemic microvascular reactivity and plasma levels of homocysteine in vegetarian individuals of the vegan type.
- Trial name
- NCT02961972
- Testing
- monohydrate and micronized creatine
- Where
- Brazil
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Vitamin D Deficiency, Hypertension
Vitamin D Deficiency in Patients With Hypertension
This study will evaluate the effects of Vitamin D replacement and the effects of an approved medication for hypertension, aliskiren (Tekturna), in patients with high blood pressure who have low levels of vitamin D in their blood.
- Trial name
- NCT00974922
- Testing
- Aliskiren, Cholecalciferol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UConn Health
Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy
The Effect of Etelcalcetide on CKD-MBD
The proposed study will investigate the effects of etelcalcetide on the bone and blood-vessel health in patients with CKD-MBD. The investigators will test if etelcalcetide makes bone and blood-vessels healthier.
- Conditions
- Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy, Vascular Calcification, Hyperparathyroidism; Secondary, Renal
- Trial name
- Parsabiv-MBD (NCT03960437)
- Testing
- Etelcalcetide
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Thomas Nickolas, MD MS
Vitamin D Deficiency
The Genetic Effects on Vitamin D Supplementation
Vitamin D is essential for skeletal growth and bone health, deficiency causes rickets and osteomalacia. In the UK 29% of adults have vitamin D deficiency. It is recommended all adults take 10µg vitamin D supplement daily.
- Trial name
- NCT05802433
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Hypovitaminosis D
Prospective Monocentric Registry of Patients Undergoing Vitamin D Treatment at San Raffaele Hospital
The Endocrinology Unit of the IRCCS San Raffaele Hospital is dedicated to establishing a prospective single-center registry with data from patients undergoing vitamin D supplementation, initiating their first visit to the…
- Trial name
- NCT06481111
- Testing
- supplementary treatment with vitamin D
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- IRCCS San Raffaele
X-Linked Hypophosphatemic Rickets
Effect of Burosumab on the Inflammatory Profile of Patients With X-linked Hypophosphatemic Rickets FLAM-XLH
X-linked hypophosphataemia (XLH) is a rare genetic disorder associated with increased circulating levels of the hormone FGF23, most commonly through mutation of the PHEX gene.
- Trial name
- FLAM-XLH (NCT06248632)
- Testing
- Expression of inflammatory markers (Il6, Il8, Il1β, CXCL1, CCL2, CXCR3, Il1R, Il6R)
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
HIV/AIDS, Vitamin D Deficiency
Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV
Supplementation with vitamin D improves HIV+ macrophages phagocytosis in vitro. There is evidence to suggest that administering vitamin D can in fact improve immune function in individuals.
- Conditions
- HIV/AIDS, Vitamin D Deficiency, Smoker Lung
- Trial name
- NCT03270709
- Testing
- Vitamin D3 450,000 IU orally
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Emory University
Osteoporosis
The Relationship Between the Residual Renal Function and Osteoporosis Treatment
The relationship between osteoporosis drugs and kidney damage is unclear. In this study, we plan to reveal relationship between osteoporosis drugs and kidney damage.
- Trial name
- NCT02304887
- Testing
- Bis, SERM Teriparatide, Denosumab
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Toshihiko Kono
Vitamin B6 Deficiency
Vitamin B6 Dependence of One-Carbon Metabolism
Marginal vitamin B6 deficiency, which occurs commonly worldwide, leads to a cellular deficiency of the coenzyme pyridoxal phosphate (PLP).
- Trial name
- NCT00877812
- Testing
- Arm 1 glycine and leucine, Arm 2 Intervention of Serine and methionine infusion
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heart Failure, Vitamin D Deficiency
Effects of Cholecalciferol Supplementation in Patients With Chronic Heart Failure and LOw vITamind D Levels
The purpose of this study is to determine whether cholecalciferol supplementation in patients with chronic heart failure and low vitamin D levels improves: 1. performance at six minutes walking test 2.
- Trial name
- ECSPLOIT -D (NCT01477801)
- Testing
- CHOLECALCIFEROL
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Azienda Unita' Sanitaria Locale Di Modena
Vitamin D Deficiency
Effect of Vitamin D Treatment on Fatigue
Primary objective -Change in Fatigue Assesment Score (FAS) between the first visit (baseline) and 28 (+maximum 7) days after oral administration of 100 000 E vitamin D (Cholecalciferol).
- Trial name
- NCT02022475
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Vitamin D Deficiency, Preterm Infants
Vitamin D Supplementation for Extremely Preterm Infants
The study hypothesis states that giving early enteral Vitamin D supplementation to preterm infants will decrease respiratory morbidity in extremely preterm infants.
- Conditions
- Vitamin D Deficiency, Preterm Infants, Bronchopulmonary Dysplasia
- Trial name
- NCT01600430
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Overweight, Hypovitaminosis D
Effects of Vitamin D Supplementation on Obesity, Inflammatory and Metabolic Markers
46 eligible overweight women with hypovitaminosis D are assigned to either vitamin D or control group using block randomization method.
- Trial name
- NCT05376865
- Testing
- Vitamin D supplement
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani, Ph.D.
Hypophosphatasia
Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)
This clinical trial was conducted to study hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT01176266
- Testing
- asfotase alfa
- Where
- 23 sites in United States, Australia and 10 more
- Volunteers
- 69 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
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