Clinical trials: Vitamin Deficiencies
Vitamin D Deficiency
Rapid Normalization of Vitamin D Deficiency in PICU
Vitamin D plays an important role in calcium balance, heart and lung health, inflammation, infection prevention, and muscle strength.
- Trial name
- VITdALIZE-KIDS (NCT03742505)
- Testing
- Cholecalciferol
- Where
- 10 sites in Canada
- Volunteers
- 424 people
- Sponsor
- Children's Hospital of Eastern Ontario
Nutritional Status, Nutrient Deficiency
Adults Nutrition as a Protective or Health-risk Factor
To obtain up-to-date data on nutrient intakes in adults, a national dietary survey - the EU Menu study will be conducted during 12 consecutive months in 2017/2018, providing data on the consumption of foods and enabling the…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NUTRIHEALTH (NCT03284840)
- Testing
- Assessement of nutritional status, Thyroid size
- Where
- 3 sites in Slovenia
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Diabetes Mellitus, Type 2, Hypertension
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Vitamin D Deficiency
- Trial name
- VDIM (NCT03348280)
- Testing
- Blood draw
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Restless Leg Disorder, Renal Disease Bone
Cholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney Disease
Restless leg syndrome (RLS) is sleep disorder characterized by an unpleasant feeling in the lower limbs, which can be accompanied by paresthesias, and need for urgent movement of the legs.
- Conditions
- Restless Leg Disorder, Renal Disease Bone, Renal Disease, End Stage, Hyperparathyroidism, Secondary
- Trial name
- RLS (NCT03063190)
- Testing
- Vitamin D
- Where
- Brazil
- Sponsor
- University of Sao Paulo General Hospital
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Medication and Supplement Use, Pregnant Women
A Cross-sectional Study Evaluating Pregnancy Related Use of Vitamins and Medication
This cross-sectional study will try to give answers to the following project aims: To provide an overview of the prevalence of health products' use among Belgian pregnant women (prescription and OTC medication, vitamin…
- Trial name
- PREVIM (NCT03105583)
- Testing
- Medication use during pregnancy, Supplement use during pregnancy, Vitamin status of a pregnant woman
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Vitamin D Deficiency
Vitamin D Supplementation and Sunlight Exposure in Brazilian Women Living in Opposite Latitudes (The D-SOL Study)
There is a consensus that vitamin D deficiency is a public health issue because of its implications in several diseases including, osteopenia, osteomalacia, heart disease, diabetes (type I and II), inflammatory diseases, multiple…
- Trial name
- D-SOL (NCT03318029)
- Testing
- Vitamin D supplementation
- Where
- 2 sites in Brazil, United Kingdom
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Hypertension, Hyperhomocysteinemia
Feasibility Study of the Intensive Systolic Blood Pressure Control
The purpose of the current feasibility study is to test whether the blood pressure level of the study patients can be effectively and safely managed according to the intensive antihypertensive treatment protocol.
- Trial name
- NCT02817503
- Testing
- Standard BP control, Moderate BP control, Intensive BP control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Alcoholics
Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy
Scurvy, or latent scurvy, may be underestimated in developed countries, but continue to be described, often as case report. Little is known about the prevalence of vitamin C deficiency in a specific population as withdrawal…
- Trial name
- NCT03467022
- Testing
- Vitamin C
- Volunteers
- 47 people
- Sponsor
- SCP Battistelli
Cardiovascular Disease, Chronic Kidney Disease
Vascular Risk After Kidney Transplantation
Hypothesis: Nontraditional risk factors, such as inflammation, vitamin D deficiency, elevated PTH, insulin resistance, homocysteine, or uric acid, contribute to cardiovascular disease progression after kidney transplant.
- Conditions
- Cardiovascular Disease, Chronic Kidney Disease, Diabetes, Vitamin D Deficiency
- Trial name
- NCT00374595
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- University of Nebraska
Vitamin D Deficiency
Physical Exercise and Diet Management in Vitamin D Deficient Females
The purpose of this study was to determine if home based physical exercises protocol and Diet management has an effect on functional performance and depression level related to vitamin D deficiency in females.
- Trial name
- NCT06114381
- Testing
- Home Based Physical Exercise, Vitamin D3 Supplements, Diet Management
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Badr University
Hemodialysis Patients, Vitamin D Insufficiency
Effect of Omega-3 Fatty Acid on Vitamin D Activation
Extra-renal sources of 1, 25-dihydroxyvitamin D can be increased to normal serum 1, 25-dihydroxyvitamin D levels in chronic kidney disease patients after administration of high dose 25-hydroxyvitamin D.
- Conditions
- Hemodialysis Patients, Vitamin D Insufficiency, Vitamin D Deficiency
- Trial name
- NCT01596842
- Testing
- Omega-3 fatty acid ethylester 90, Olive oil, cholecalciferol
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Dong-A University
COVID-19 Pandemic, Vitamin D Deficiency
COVID-19 and Vitamin D: Length of Hospital Stay and Mortality
The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition.
- Trial name
- NCT05221983
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Yuksek Ihtisas University
Vitamin D Deficiency
Vitamin D Deficiency, Insulin Resistance and FGF-23
The purpose of this project is to determine if treating vitamin D deficiency decreases insulin resistance and improves insulin secretion in healthy volunteers.
- Trial name
- NCT00491322
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypocalcemia, Rickets
Studies With 1,25-Dihydroxycholecalciferol
Vitamin D in the diet undergoes changes in the liver and kidneys to several forms. Patients suffering from disorders with Vitamin D resistance are unable to absorb calcium from food.
- Trial name
- NCT00001151
- Testing
- 1,25-Dihydroxycholecalciferol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
X-linked Hypophosphatemia (XLH)
Retrospective and Prospective Disease Progression and Quality of Life in XLH
There is limited empirical data documenting disease progression and impact on quality of life for patients with X-linked hypophosphatemia (XLH).
- Trial name
- NCT04049877
- Testing
- None - Observational study
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Medialis Ltd.
Pre-Eclampsia, Depression
Preeclampsia Research on Vitamin D, Inflammation, & Depression
This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression.
- Conditions
- Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
- Trial name
- PROVIDE (NCT03018132)
- Testing
- mental health screening, education and referral program
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Chronic Kidney Disease Stage 5
Efficacy of Plant-protein Diets in Patients With Chronic Kidney Disease
The purpose of this study is to evaluate the efficacy of plant-protein diets for 12 weeks in patients with advanced chronic kidney disease.
- Trial name
- NCT05350098
- Testing
- Plant-protein Diets, Control Diets
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Osaka University
X-Linked Hypophosphatemia
Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)
The primary objectives of this study are to: Assess the long-term safety of KRN23 subcutaneous (SC) administration in adult subjects with XLH Assess the proportion of subjects achieving serum phosphorus levels in the normal range…
- Trial name
- NCT02312687
- Testing
- KRN23
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Kyowa Kirin, Inc.
Leg Cramps, Nocturnal
Vitamin D for Painful Nocturnal Leg Cramps
1. Research question: Does vitamin D reduce the frequency and severity of nocturnal leg cramps in older persons who previously took quinine for leg cramps? 2.
- Trial name
- NCT00715429
- Testing
- vitamin d
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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