Clinical trials: Vitamin Deficiencies
Hypophosphatasia (HPP)
Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)
This clinical trial studied the safety and efficacy of asfotase alfa in children with HPP compared to a historical control group.
- Trial name
- NCT00952484
- Testing
- asfotase alfa
- Where
- 2 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Vitamin D Deficiency
A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families
Vitamin D deficiency is common. It is caused by limited sun availability together with a low supply of vitamin D in the food system. There is a high prevalence of low vitamin D status around the world.
- Trial name
- Fam-D-Bread (NCT07481240)
- Testing
- Fortified Bread, Unfortified bread
- Where
- 2 sites in Ireland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University College Cork
Vitamin D Deficiency
Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients
Asthma-COPD overlap (ACO) is a new entity in the world of respiratory ailments. The respiratory tract of these patients are continuously exposed to oxidants (due to cigarette smoking) causing oxidative stress.
- Trial name
- NCT03931889
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Vitamin A Deficiency, Pediatric
Efficacy and Safety of Vitamin A Treatment for Children With Sepsis
The prevalence of vitamin A deficiency was found high in children with sepsis. Whether those patients will benefit from the vitamin A supplementation is unknown.
- Conditions
- Vitamin A Deficiency, Pediatric, Sepsis
- Trial name
- NCT04127968
- Testing
- Vitamin A, Oil
- Volunteers
- 450 people
- Sponsor
- West China Hospital
Vitamin D, Iron Deficiency and Overload
Can Vitamin D Replacement Correct Chronic Disease Anemia?
This prospective, single-arm interventional pilot study evaluated whether vitamin D supplementation alone improves iron status in adults with inflammatory bowel disease (IBD) who are in clinical remission and have concurrent…
- Conditions
- Vitamin D, Iron Deficiency and Overload, Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
- Trial name
- NCT07673497
- Testing
- Cholecalciferol (Vit D3)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gazi University
Tooth Loss, Vitamin D3 Deficiency
Dental Implants Rehabilitation in Patients With Vitamin D3 Imbalance
Interventional retrospective prospective randomized clinical trial (RCT) in parallel groups. The sample size is 384 patients with loss of teeth and vitamin D imbalance.
- Conditions
- Tooth Loss, Vitamin D3 Deficiency, Osteomalacia
- Trial name
- NCT04841213
- Testing
- Dental implantation
- Where
- 2 sites in Russia
- Volunteers
- 384 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Vitamin D Deficiency
Vitamin D in Systemic Sclerosis Patients With Periodontitis
Vitamin D has been considered to possess anti-inflammatory and antimicrobial activity which may be a link for the known interaction of Systemic Sclerosis (SSc) and coronary heart disease (CHD).
- Trial name
- NCT04066842
- Testing
- Observation
- Where
- Italy
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Messina
Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder
Phosphate Assessment in Chronic Kidney Disease Patients Study
The proposed pilot feeding study aims to explore novel pathways in phosphate metabolism and identify new biomarkers, as well as to develop a compound index for assessing phosphate overload with high validity and reliability.
- Trial name
- PACK (NCT07368946)
- Testing
- Dietary Phosphorus Intake
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Vitamin Deficiency
Effect of Vitamin D Supplementation on Muscular Strength, Musculoskeletal Pain and Headache
The primary aim of the present trial is to study the effect of daily vitamin D supplementation on muscular power and force among non-western immigrants living in Oslo, Norway, and secondarily to study the effect of…
- Trial name
- NCT01263288
- Testing
- cholecalciferol
- Where
- Norway
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Per Lagerlov
Hematopoietic Stem Cell Transplantation, Delirium
High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation
Purpose: To conduct a randomized controlled pilot study investigating the use of high dose intravenous (IV) thiamine to prevent delirium and mitigate the long-term effects of delirium, including health-related quality of life…
- Conditions
- Hematopoietic Stem Cell Transplantation, Delirium, Thiamine Deficiency
- Trial name
- NCT03263442
- Testing
- Thiamine, Normal saline
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Micronutrient Deficiencies, Hyperhomocysteinemia
Effectiveness of a Micronutrient Supplement to Lower Plasma Homocysteine MDEG2 Pilot Supplementation Trial
This micronutrient supplementation study is a 3-arm randomized controlled trial, unblinded, with 125 women per arm. Non-pregnant, non-lactating healthy women of reproductive age in West Kiang, The Gambia, will be randomized to 12…
- Trial name
- MDEG2-PST (NCT03431597)
- Testing
- novel micronutrient, existing micronutrient supplement, UNIMMAP
- Where
- The Gambia
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Vitamin D Deficiency, Inflammatory Bowel Diseases
Vitamin D Status in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), comprising crohn's disease (CD) and ulcerative colitis (UC), is a a chronic, relapsing-remitting systemic disease.
- Trial name
- vdsinibd (NCT03496246)
- Testing
- serum total 25 hydroxycholecalciferol 25(OH) vitamin D, complete blood count (CBC), serum calcium level
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Multiple Myeloma
VitD3 Supplementation in Patients With Multiple Myeloma
The goal of this clinical trial is to evaluate post-transplant immune reconstitution and lymphocyte recovery as well as the 3-year progression-free survival of patients with multiple myeloma in two treatment arms.
- Trial name
- NCT05846880
- Testing
- Lenalidomide, Maintenance Vitamin D, No maintenance Vitamin D
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Amany Keruakous, MD, MS.
Vitamin B-12 Deficiency
THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants
Infancy may be associated with a risk of micronutrient depletion due to the high demands of rapid growth. This is particularly true when preterm birth occurs, as the period before term exhibits the highest rate of bodily growth…
- Trial name
- B-BABIES (NCT07163962)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Vitamin D Deficiency, Preterm Infants
Multi-dose Vitamin D Supplementation in Preterm Infants
Preterm newborns are born with lower vitamin D stores. Although vitamin D supplementation is recommended there is no consensus regarding the adequate dose of supplementation for preterm infants.
- Trial name
- NCT02941185
- Testing
- Devit-3 Oral Drop
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Vitamin D Deficiency, Pre-Eclampsia
Vitamin D in Pregnancy
Danish pregnant women are recommended ad daily vitamin D supplement of 10 µg. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an…
- Conditions
- Vitamin D Deficiency, Pre-Eclampsia, Fetal Growth Retardation, Gestational Diabetes
- Trial name
- GRAVITD (NCT04291313)
- Testing
- Vitamin D3 (90µg), Vitamin D3 (10µg)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Vitamin D Deficiency
Controlled, Randomized, Four-arm Comparative, Open Label, Multi-centric Clinical Trial to Compare the Efficacy and Safety Parameters of the Once-a-week or Once-a-month Administered 7000 IU, or 30000 IU Vitamin D (Cholecalciferol) to a 1000 IU Dosage Applied Daily in Vitamin D Deficient Patients
Circa-annual variations in 25-hydroxyvitamin D [25(OH)D] levels have been well established, and there also seems to be an effect of season on bone turnover and bone mass.
- Trial name
- NCT02069990
- Testing
- Cholecalciferol
- Where
- 2 sites in Hungary
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
HIV Disease, Vitamin D Deficiency
Vitamin D Supplementation in HIV-infected Youth
Along with its effects on bone metabolism, vitamin D is an important modulator of the immune system. Experimental studies have shown that the active metabolite of vitamin D [1,25(OH)2D] is able to skew the T cell compartment into…
- Conditions
- HIV Disease, Vitamin D Deficiency, Hypovitaminosis D, Hyperparathyroidism
- Trial name
- NCT01656070
- Testing
- oral cholecalciferol 1000000 UI (vitamin D3)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Hypovitaminosis D, Insulin Resistance
Comparative Effectiveness of Vitamin D and Repletion Strategies
The importance of vitamin D (VitD) in the prevention and treatment of human health conditions has gained increased attention in recent years.
- Conditions
- Hypovitaminosis D, Insulin Resistance, Diabetes
- Trial name
- CEDARS (NCT01524874)
- Testing
- Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Vitamin B 12 Deficiency
Effects of Vitamin B12 Treatment in Singers
In this study, the investigators aim to assess if vitamin B12 treatment demonstrates a beneficial effect on voice performance. If so, they wish to examine the relationship between the vitamin B12 treatment and the study…
- Trial name
- NCT03437824
- Testing
- Cyanocobalamin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.