Clinical trials: Vitamin Deficiencies
Gestational Hypertension, Preeclampsia
B Vitamin Deficiency and Pregnancy Complications
This case-control study aims to investigate the association between B vitamins and gestational hypertension or preeclampsia.
- Trial name
- NCT05720650
- Testing
- No intervention
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Westlake University
Vitamin D Deficiency
Effects of Vitamin D and Calcium Supplementation on Health and Well-being of Vitamin D Deficient UAE Citizens
The trial plan to determine whether a daily capsule containing vitamin D(3) (2000 IU), calcium (600 mg), both, or a placebo for 6 months in UAE citizens with evidence of vitamin D deficiency will lead to a clinical benefit.
- Trial name
- NCT02662491
- Testing
- Vitamin D and calcium, Vitamin D, Calcium
- Where
- United Arab Emirates
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Vitamin D Deficiency, Pre Eclampsia
Evaluation of the Effectiveness of Vitamin D Supplementation to Pregnant Women and Their Infants in Pakistan.
Vitamin D deficiency is wide spread in South Asian population and is contributing to burden of disease in this region including Pakistan.
- Conditions
- Vitamin D Deficiency, Pre Eclampsia, Stillbirths, Low Birth Weight
- Trial name
- NCT01229189
- Testing
- Vitamin D
- Where
- Pakistan
- Volunteers
- 460 people
- Sponsor
- Aga Khan University
Choline Deficiency, Liver Injury
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
TARA-001-301 is a Phase 2b/3 randomized Open-Label Dose-Selection study with an Open-Label Extension and randomized Double-Blind, Placebo-Controlled Study with Open-Label Extension to investigate the safety and efficacy of…
- Trial name
- THRIVE-3 (NCT06910943)
- Testing
- Choline Chloride for Injection
- Where
- 18 sites in United States, Belgium and 4 more
- Volunteers
- 129 people
- Sponsor
- Protara Therapeutics
PCOS, Depression
Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Open-label randomized clinical trial assessing the efficacy of Metformin versus Vitamin D in improving symptoms of depressed mood in polycystic ovary syndrome.
- Conditions
- PCOS, Depression, Vitamin D Deficiency, Insulin Resistance
- Trial name
- MINDD (NCT03380091)
- Testing
- Metformin, Vitamin D
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endstage Renal Disease
The Effect of Increasing Dialysate Magnesium on Calcification Propensity in Subjects on Haemodialysis
The purpose of this trial is to examine the effect of increasing dialyse magnesium on serum calcification propensity in subjects with end-stage renal disease treated with haemodialysis.
- Trial name
- NCT02977117
- Testing
- Dialysate magnesium (1.0 mmol/L), Dialysate magnesium (0.5 mmol/L)
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- Iain Bressendorff
Respiratory Infection
Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents
This study will test the role of high dose vitamin D supplementation in prevention of acute respiratory infection in older nursing home residents.
- Trial name
- NCT01102374
- Testing
- High Dose Vitamin D, Standard Dose Vitamin D, Usual Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Colorado, Denver
Acute Respiratory Distress Syndrome, Vitamin D Deficiency
Vitamin D to Improve Outcomes by Leveraging Early Treatment
Vitamin D deficiency is a common, potentially reversible contributor to morbidity and mortality among critically ill patients. We conducted a randomized, double-blind, placebo-controlled, phase 3 trial of early vitamin D3…
- Conditions
- Acute Respiratory Distress Syndrome, Vitamin D Deficiency, Critical Illness
- Trial name
- VIOLET (NCT03096314)
- Testing
- Vitamin D3
- Where
- 47 sites in United States
- Volunteers
- 1,358 people
- Sponsor
- Massachusetts General Hospital
Meniere Disease, Osteoporosis
Menier's Disease - Bone Density Study
Meniere's disease is a progressive and debilitating inner ear disease characterised by vertigo and hearing loss. Several studies have linked Menierws disease with lower bone density and lower vitamin D levels.
- Conditions
- Meniere Disease, Osteoporosis, Osteopenia, Vitamin D Deficiency
- Trial name
- NCT05322538
- Testing
- vitamin D plasma levels baseline, Dual-energy X-ray absorptiometry at baseline, cervical Vestibular evoked myogenic potentials at baseline
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Obesity, Endothelial Dysfunction
Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents
Vitamin D deficiency has been linked to endothelial dysfunction in adults. Obese adolescents have a high prevalence of Vitamin D deficiency as well as evidence of endothelial dysfunction.
- Conditions
- Obesity, Endothelial Dysfunction, Vitamin D Deficiency
- Trial name
- NCT01746264
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetic Peripheral Neuropathy, B Vitamin Deficiency
The Nutritional Benefits of Metanx in Patients With Diabetic Peripheral Neuropathy (MEDIAN)
The objectives of the MEDIAN study are to evaluate the short-term and long-term safety and nutritional benefits of Metanx® versus placebo in subjects with mild to moderate diabetic peripheral neuropathy (DPN).
- Trial name
- MEDIAN (NCT01990092)
- Testing
- Metanx
- Where
- 25 sites in United States
- Volunteers
- 238 people
- Sponsor
- Pamlab, Inc.
Vitamin D Deficiency
Environmental & Genetic Influences on Vitamin D Status
The purpose of this study is to determine the effect of environmental and genetic influences on Vitamin D status.
- Trial name
- NCT01208636
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Creighton University
Vitamin D Deficiency
Influence of Vitamin D Treatment on Multi-systemic Functions in Young Men With Vitamin D Deficiency Due to Work Conditions
Vitamin D has multiple systemic effects: bone and calcium metabolism, muscle function, insulin responsiveness, body-composition regulation, cell differentiation, and the immune system.
- Trial name
- NCT01016184
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Vitamin D Deficiency
Study Vitamin D in Healthy Individuals
To obtain sufficient specimens and correlating clinical data from a well-controlled prospective clinical trial collecting specimens from healthy subjects t on vitamin D assays, and to establish a collection of specimens that will…
- Trial name
- NCT02250625
- Where
- United States
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Fujirebio Diagnostics, Inc.
X-linked Hypophosphatemia
A Study of KRN23 in X-linked Hypophosphatemia
The primary objective of this study is to assess the safety and tolerability of KRN23 after a single intravenous (IV) and subcutaneous (SC) administration in XLH patients.
- Trial name
- NCT00830674
- Testing
- KRN23
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Vitamin D Deficiency
Community Interventional Trial (CITFOMIST)
The cluster randomized trial (CITFOMIST) was conducted on 15-19-year old guidance and high school students of both genders from different districts of Tehran, the Iranian capital, in winter 2011.
- Trial name
- CITFOMIST (NCT02035423)
- Testing
- 120 IU milk, 200 IU Milk, Non-Fortified Milk
- Where
- Iran
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Vitamin K Deficiency, End Stage Renal Disease
The Effect of Vitamin K2 Supplementation on Arterial Stifness and Cardiovascular Events in PEritonial DIAlysis
VIKIPEDIA is a multi-centre, placebo-controlled, randomized, open-label intervention clinical trial on Peritoneal Dialysis (PD) patients.
- Conditions
- Vitamin K Deficiency, End Stage Renal Disease, Peritoneal Dialysis, Arterial Stiffness
- Trial name
- VIKIPEDIA (NCT04900610)
- Testing
- MenaQ7 ®, Nattopharma, ASA, Hovik, Norway
- Volunteers
- 120 people
- Sponsor
- Aristotle University Of Thessaloniki
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism
This is a phase 3, multi-center, randomized, double-blind, placebo-controlled study in children with stage 3-4 chronic kidney disease (CKD), secondary hyperparathyroidism (SHPT) and vitamin D insufficiency.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Vitamin d Deficiency, Secondary Hyperparathyroidism
- Trial name
- NCT05543928
- Testing
- CTAP101
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- OPKO Health, Inc.
Hypophosphatasia
Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan
This is a multicenter study in Japan. Eleven sites which have already participated in the investigator-initiated clinical study (Early Access Program) will participate in this study.The objective of this study is to gain further…
- Trial name
- NCT02531867
- Testing
- Asfotase Alfa
- Volunteers
- 13 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
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