Clinical trials: Vitamin Deficiencies
Vitamin D Deficiency, Immunosuppression
Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study
Purpose: To examine whether helminth infection during pregnancy alters Vitamin-D-metabolism and reactivity of the child's immune system Hypothesis: Helminth infection during pregnancy is associated with altered Vitamin D levels…
- Trial name
- HELMVIT (NCT04324853)
- Testing
- Microscopy ( Urine filtration), UCAA test, qPCR,, Microscopy (Kato Katz, Coproculture, Harada Mori, MIF), qPCR,
- Where
- Gabon
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Endometriosis, Vitamin D Deficiency/Insufficiency
Analysis of Vitamin D and VDR Expression in Endometriosis: A Case-Control Study
The goal of this cross-sectional prospective matching study is to evaluate whether serum vitamin D levels and vitamin D receptor (VDR) expression are associated with the presence and severity of endometriosis in women of…
- Conditions
- Endometriosis, Vitamin D Deficiency/Insufficiency, Vitamin D Status
- Trial name
- NCT06289257
- Testing
- Vitamin D level, Vitamin D receptor
- Where
- Thailand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
COVID-19 Pandemic, D Vitamin Deficiency
Impact of Vitamin D Supplementation on COVID-19 Vaccine Response and IgG Antibodies in Deficient Women.
Decreased immunity in individuals causes a decrease in vaccine response, and vitamin D worsens this course. Vitamin D is thought to be a vitamin that can strengthen the innate immune response, inhibit the adaptive system, and…
- Conditions
- COVID-19 Pandemic, D Vitamin Deficiency, Antibody Hypersensitivity
- Trial name
- CoVıD-19 (NCT05447065)
- Testing
- Vitamin D supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ege University
Influenza Vaccine, Immune Response
Evaluation of Metabolic Predictors of Influenza Vaccine Immune Response in the Singapore Elderly Population - the DYNAMIC Trial
The trial aims to evaluate role of metabolic factors including systemic 25-OH D and diabetes in the adaptive immune response (haemagluttination inhibition titer) to influenza vaccine in the elderly.
- Conditions
- Influenza Vaccine, Immune Response, Elderly, Vitamin D Deficiency
- Trial name
- NCT03399357
- Testing
- Influenza Vaccine
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Type2diabetes
Type 2 Diabetes and Blood Brain Barrier Improvement
The majority of T2DM adults show thiamine (vitamin B1) deficiency which may contribute to impaired function. This study will examine patients with T2DM through brain MRI scans, cognition assessments, blood tests, and…
- Trial name
- NCT06322212
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hypovitaminosis D
The Effect of Hypovitaminosis D and Vitamin D Supplementation on Fracture Nonunion Rates
The purpose of the study is to determine whether vitamin D supplementation in patients with hypovitaminosis D can decrease nonunion (failure to heal) incidence in patients with fractures of the humerus, femur, or tibia.
- Trial name
- VitD (NCT01691833)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Wake Forest University Health Sciences
COVID, Vitamin D Deficiency
The LEAD COVID-19 Trial: Low-risk, Early Aspirin and Vitamin D to Reduce COVID-19 Hospitalizations
Although the novel SARS-CoV-2 virus (COVD-19) is classified as an acute respiratory infection, emerging data show that morbidity and mortality are driven by disseminated intravascular coagulopathy.
- Conditions
- COVID, Vitamin D Deficiency, Coagulopathy, Disseminated Intravascular Coagulation
- Trial name
- LEAD COVID-19 (NCT04363840)
- Testing
- Aspirin 81 mg, Vitamin D
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Vitamin A Deficiency, Vitamin D Deficiency
Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Birth Weight Infants
Vitamins A, D, and E play important roles in humans, such as vision function, immune function, bone metabolism, cell growth and differentiation and oxidation resistance.
- Conditions
- Vitamin A Deficiency, Vitamin D Deficiency, Vitamin E Deficiency, Very Low Birth Weight Infants
- Trial name
- NCT03876704
- Testing
- High dose of fat-Soluble Vitamin, Conventional dose of fat-Soluble Vitamin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Vitamin D Deficiency, Critical Illness
Prevalence of Deficiency of Vitamin D in Critically Ill Patients
Vitamin D has been shown to related to clinical outcomes in critically ill patients. The object of this study is to investigate the prevalence of Vitamin D deficiency in critically ill patients with various length of ICU stay .
- Trial name
- NCT03639584
- Where
- Taiwan
- Volunteers
- 662 people
- Sponsor
- National Taiwan University Hospital
Vitamin A Deficiency, Low Serum Retinol
Efficacy of β-carotene Biofortified Maize in Reducing Vitamin A Deficiency Among Children
The purpose of this cluster-randomized trial is to examine whether daily consumption of β-carotene biofortified maize flour can reduce the prevalence of vitamin A deficiency and improve the vitamin A status and among 4-8 year old…
- Trial name
- NCT01695148
- Testing
- β-Carotene Biofortified Maize Flour, White Maize Flour
- Where
- Zambia
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Covid 19, Vitamin D Deficiency
Vitamin D Testing and Treatment for COVID 19
This study will measure vitamin D levels in adults with COVID 19. Participants with low levels of vitamin D will be entered into an open label trial of supplementation with vitamin D.
- Trial name
- NCT04407286
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Arizona State University
Vitamin D Deficiency
Different Vitamin D Preparations & FGF23 in Humans
Fibroblast growth factor 23 (FGF23) is a new hormone which controls phosphate and vitamin D levels in humans. Excess FGF23 is associated with an increased risk of death in patients with chronic kidney disease.
- Trial name
- NCT00957879
- Testing
- Ergocalciferol, Calcitriol
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Scurvy
"Vitamin C Deficiency in Hospitalized Adults: Systematic Screening Vs. Traditional Judgment - a Before-and-After Observational Study"
Brief Summary of the Study The goal of this observational study is to assess the incidence of vitamin C deficiency among hospitalized adults presenting with hemorrhagic signs.
- Trial name
- NCT06876545
- Testing
- systematical screening of at risk patients based on predefined hemorrhagic criteria
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Internist.Ro
Vitamin D Deficiency, Immune Health
Estimation of the Dietary Requirement for Vitamin D in Ethnic Groups
The aim of this study is to perform a double-blind, randomised, dose-response trial of vitamin D3 supplementation in United Kingdom (UK)-dwelling adults of white European, South Asian, and black African/Caribbean ethnicity to…
- Conditions
- Vitamin D Deficiency, Immune Health, Muscle Function
- Trial name
- NCT06067477
- Testing
- Vitamin D Supplement
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Vitamin Deficiency
Effectiveness of a Nutraceutical in Raising Circulating Serum Vitamin, Mineral and Amino Acid Levels in Patients.
The purpose of this study is to correlate the findings of an early study with current data.
- Trial name
- NCT04054505
- Testing
- EZPAK
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Optimal Health Research
Uremia, Chronic Renal Failure
Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events
Homocysteine recently gained access to the category of risk factor for the development of atherosclerotic cardiovascular disease in the general population.
- Conditions
- Uremia, Chronic Renal Failure, Hemodialysis, Hyperhomocysteinemia
- Trial name
- NCT00317005
- Testing
- folate treatment
- Where
- 2 sites in Brazil
- Volunteers
- 186 people
- Sponsor
- Universidade Estadual de Londrina
Vitamin D Deficiency, Hypocalcemia
Effect of Vitamin D Supplement on Disease Activity in SLE
To study the effect of vitamin D supplementation on disease activity of SLE ( SLEDAI-2K ) and IL-6 level
- Conditions
- Vitamin D Deficiency, Hypocalcemia, Hyperparathyroidism, Systemic Lupus Erythematosus (Disorder)
- Trial name
- NCT05260255
- Testing
- vitamin D2 ( calciferol )
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Hypovitaminosis D
Rapid Normalization of Vitamin D in Critically Ill Children: A Phase II Dose Evaluation Randomized Controlled Trial
Documented roles for vitamin D in calcium homeostasis, cardiovascular and respiratory health, inflammation, innate immunity, and neuromuscular function have led to the hypothesis that deficiency might represent a modifiable risk…
- Trial name
- VITdAL-PICU (NCT02452762)
- Testing
- Vitamin D3
- Where
- 4 sites in Austria, Canada and 1 more
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Eastern Ontario
Vitamin A Deficiency
Stopping Postpartum Vitamin A Supplementation: Missing Concealed Benefit
The purpose of this study is to evaluate the effect of post-partum maternal vitamin A supplementation on breast milk bioactive compounds and immune status, growth and morbidity of children in the first four months of life.
- Trial name
- NCT02043223
- Testing
- Vitamin A (<3-day postpartum), Vitamin A (6 wk postpartum), Vitamin A (<3-day and 6 wk postpartum)
- Where
- Bangladesh
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh