Clinical trials: Vitamin Deficiencies
Sickle Cell Disease, Vitamin D Deficiency
Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether oral vitamin D supplementation can decrease lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Acute Chest Syndrome, Asthma
- Trial name
- NCT01443728
- Testing
- Experimental: Vitamin D3 100,000 IU, Active Comparator: Vitamin D3 12,000 IU
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Gary M Brittenham, MD
Vitamin C Deficiency, Vitamin D Deficiency
Vitamin Deficiency and Blood Pressure in Hospitalized Jewish General Hospital (JGH) Patients
There is suggestive evidence that vitamin C and vitamin D deficiency may increase blood pressure across the range of blood pressures from normal to elevated.
- Trial name
- NCT00921622
- Testing
- Vitamin D, Vitamin C
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Jewish General Hospital
Chronic Kidney Disease, Vitamin D Deficiency
Vitamin D and Coronary Calcification Study
Patients with chronic kidney disease (CKD) have a higher mortality rate than the general population, with cardiovascular disease (CVD) accounting for approximately 50% of deaths.
- Conditions
- Chronic Kidney Disease, Vitamin D Deficiency, Coronary Calcification, Disorders of Calcium and Bone Metabolism
- Trial name
- VCOR (NCT00752102)
- Testing
- Calcitriol (Rocaltrol®), Paricalcitol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Joslin Diabetes Center
Asthma, Vitamin D Deficiency
A Study to Investigate the Effect of Vitamin D3 Supplementation on Asthma Symptoms in Adults With Asthma (VITDAS)
Asthma is a disease characterised by chronic inflammation of the airways leading to symptoms including periods of shortness of breath, wheezing and a tight chest due to airway narrowing in affected patients.
- Conditions
- Asthma, Vitamin D Deficiency, Nutritional Deficiency, Inflammation
- Trial name
- VITDAS (NCT04117581)
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Chester
Cobalamin Deficiency
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
A 3 months randomized, placebo-controlled study on the effect of toothpaste fortified with vitamin B12 on vitamin B12 status markers and related metabolic markers.
- Trial name
- NCT02679833
- Testing
- Cyanocobalamin
- Where
- 2 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Vitamin D Deficiency
The Variability of 25-hydroxyvitamin D Response From Crystalline 25-hydroxyvitamin D3
The investigators hypothesize that native vitamin D will have more variability in 25(OH)D dose response when compared to a given equipotent dose of 25-hydroxyvitamin D3.
- Trial name
- NCT01633658
- Testing
- cholecalciferol, 25(OH)D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Psoriasis, Metabolic Syndrome
Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis
The purpose of this study is to determine whether supplementation with oral vitamin D (cholecalciferol) improves metabolic parameters in patients with moderate to severe psoriasis.
- Conditions
- Psoriasis, Metabolic Syndrome, Vitamin D Deficiency
- Trial name
- NCT02271971
- Testing
- Vitamin D3
- Where
- Chile
- Volunteers
- 39 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Deficiency, Vitamin C
Hypovitaminosis C Prevalence and Risk Factors in an Acute Geriatric Unit
Vitamin C is essential for numerous biological processes as it acts as a cofactor in various hydroxylation reactions, but also as a powerful antioxidant.
- Trial name
- HYPO-VIT-C (NCT05668663)
- Testing
- Plasmatic Vitamin C concentrations (known as ascorbemia) on a single blood sample
- Where
- France
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease, Chronic Kidney Disease
Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease
The purpose of this study is to determine if vitamin D supplementation changes the results of certain tests associated with inflammation in the body using an oral, synthetic form of vitamin D called paricalcitol.
- Conditions
- Coronary Artery Disease, Chronic Kidney Disease, Hypovitaminosis D, Secondary Hyperparathyroidism
- Trial name
- VINCA-CKD (NCT01012414)
- Testing
- paricalcitol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Thomas Jefferson University
Vitamin D Deficiency
The Role of Vitamin D in Female Reproductive Tract Immunity
The purpose of this study is to assess the impact of approximately 8 weeks of Vitamin D (VitD) and calcium supplementation, using daily versus weekly supplementation regimens, on female reproductive tract immunity.
- Trial name
- NCT02186535
- Testing
- Vitamin D and Calcium
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CONRAD
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Vitamin D Deficiency
Vitamin D in Armenia: Vitamin D Repletion Strategies With Dibase, and Vitamin D and Vitamin D Binding Protein and COVID
This is a three-arm unblinded prospective interventional study of vitamin D supplementation in participants with insufficient vitamin D at three different induction and maintenance dosing regimens (high dose, low frequency…
- Trial name
- NCT06406543
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- Armenia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Columbia University
Vitamin D Deficiency, Tuberculosis
Role of Vitamin D in Innate Immunity to Tuberculosis
The investigators proposed a pilot study preparatory to developing a randomized trial of vitamin D for the prevention of TB infection. The specific aims are presented below: 1.
- Trial name
- NCT01244204
- Testing
- Vitamin D
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Vitamin d Deficiency, Preeclampsia
25- Hydroxyvitamin D Levels in Pregnancy and Effects on Pregnancy Related Disorders
Evaluation of 25- Hydroxyvitamin D levels in pregnant women in Austria and potential related disorders Hypothesis: Austrian pregnant women are Vitamin D deficient Present vitamin D supplementation in pregnancy is insufficient…
- Conditions
- Vitamin d Deficiency, Preeclampsia, Preterm Delivery, Gestational Hypertension
- Trial name
- VIDIS (NCT04637880)
- Where
- Austria
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Vitamin D Deficiency
Vitamin D Supplementation D_SAF Pilot Study
This study is a randomised control trial (RCT) pilot study to determine the appropriate vitamin D dose for the main study. The pilot study includes three matched groups, which will form two vitamin D supplementation groups (at…
- Trial name
- NCT04033796
- Testing
- 25,000 IU, 50,000 IU
- Where
- 2 sites in United Kingdom
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Vitamin D Deficiency, Critical Illness
Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency.
The purpose of the research study is to determine whether a single high dose of vitamin D is helpful in reducing critical illness related complications in intensive care patients who are having sever vitamin D deficiency.
- Trial name
- NCT02868827
- Testing
- Cholecalciferol, Milk (Nestle)
- Where
- Saudi Arabia
- Volunteers
- 127 people
- Sponsor
- King Abdullah Medical City
Hypertension, Vitamin D Deficiency
Blood Pressure in Blacks and Calcium (BBC) and Vitamin D Study
Adequate levels of vitamin D are essential for bone health at all ages but low levels of vitamin D may also negatively impact other aspects of health such as blood pressure.
- Trial name
- BBC (NCT03070483)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Loyola University
X-linked Hypophosphatemia
Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)
The objectives of the study are to: Identify a dose and dosing regimen of burosumab, based on safety and pharmacodynamic (PD) effect, in pediatric XLH participants Establish the safety profile of burosumab for the treatment of…
- Trial name
- NCT02163577
- Testing
- burosumab
- Where
- 9 sites in United States, France and 2 more
- Volunteers
- 52 people
- Sponsor
- Kyowa Kirin, Inc.
Vitamin D Deficiency, Metabolic Syndrome
Bioavailability and Biological Effects of Vitamin D2 Contained in Mushroom
The purpose of this study is to compare the safety and efficacy of two different amounts of vitamin D2 (600 or 4000 International Units/day) provided by mushrooms added to one of the daily meals versus same doses of vitamin D3…
- Conditions
- Vitamin D Deficiency, Metabolic Syndrome, Prediabetes
- Trial name
- NCT01488734
- Testing
- Mushroom with 600 IU vitamin D2, Mushroom with 4000 IU Vitamin D2, 600 IU Vitamin D3 and untreated mushroom
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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