Clinical trials: Vitamin E
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Cardiovascular Diseases
Endothelial Function in a Sample Group of Patients From the ICARE Study
The ICARE study, clinicaltrials.gov ID number: NCT00220831 and protocol number KL-2004, is recruiting diabetic patients with haptoglobin phenotype 2-2, which are randomised to either Vitamin E 400IU per day or placebo.
- Trial name
- NCT00314379
- Testing
- Vitamin E 400IU/day
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Technion, Israel Institute of Technology
Rheumatoid Arthritis
Omega-3 and Vitamin E Supplementation in Patients With Rheumatoid Arthritis
The purpose of this study is to determine whether simultaneous supplementation with omega-3 fatty acids and vitamin E is effective in the treatment of patients with rheumatoid arthritis.
- Trial name
- NCT00399282
- Testing
- Omega-3 and Vitamin E supplementation
- Where
- Iran
- Volunteers
- 75 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Schizophrenia
Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids
This research study helps to demonstrate that adding vitamins and fats (nutritional supplements) to a diet will help reduce body weight and improve the lipid profile.
- Trial name
- NCT00211562
- Testing
- Olanzapine, Omega 3, Vitamin E+C
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Scar
Efficacy Of Tocotrienol a Natural Vitamin E In Biopsy Wound
The following two objectives are proposed in healthy subjects to characterize (1) wound closure, (2) scar formation/appearance, and (3) inflammatory response: Objective 1, (topical only - referred to as "TOP") - Topical…
- Trial name
- TOP/OTOP (NCT01579227)
- Testing
- Topical Tocotrienol (TCT), Oral Tocotrienol Capsules (TCT), Tamoxifen Cream
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Chandan K Sen
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Surgical Site Infection
Effect of Vitamin E-containing Dressing on Surgical Site Infection in Colorectal Surgery
A prospective, randomized study will be performed. Patients are randomized using a 1:1 allocation into 2 groups: patients receiving a vitamin E-containing dressing (group 1) and a conventional dressing (group 2).
- Trial name
- NCT03443141
- Testing
- Vitamin E, Standard dressing
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital General Universitario Elche
Radiation Induced Brachial Plexopathy
Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy
Radiation-induced brachial plexopathy (RIP) is a rare and severe delayed peripheral nerve complication of radiotherapy, that is spontaneously irreversible with no medical treatment to limit or reduce symptoms.
- Trial name
- PENTOCLO (NCT01291433)
- Testing
- Pentoxifylline, Tocopherol acetate, Clodronic Acid
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
The Effects of Omega 3 and Vitamin E Supplementation on the Serum Antioxidant Enzymes and Gene Expressions of PGC-1a, h TERT, FOXOs and SIRTs in CAD Patients
The aim of this study is to determine the effects of omega 3 supplementation and its concurrent supplementation with vitamin E on the serum levels of antioxidant enzymes and the expressions of the PGC-1a, h TERT, FOXO1, FOXO3a …
- Trial name
- NCT02011906
- Testing
- omega 3, vitamin E
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Tehran University of Medical Sciences
Lichen Planus
Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen Planus
Oral lichen planus (OLP) is a chronic inflammatory disease affecting the skin, mucous membranes,s and rarely scalp and nails. It is a T-cell-mediated autoimmune disease.
- Trial name
- NCT05787925
- Testing
- Topical corticosteroid and Vitamin E, Topical corticosteroid
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Hams Hamed Abdelrahman
Glaucoma, Open-Angle
Citicoline & Antioxidants in Glaucoma
To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and…
- Trial name
- NCT06355765
- Testing
- Citicoline blackcurrant supplement
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Naples
Healthy, NAFLD (Non-Alcoholic Fatty Liver Disease)
Effect of Vitamin E on Non-Alcoholic Fatty Liver Disease
One-third of the US population has non-alcoholic fatty liver disease (NAFLD) due to obesity and ~8 million of these individuals have a progressive form of the disease, non-alcoholic steatohepatitis (NASH).
- Conditions
- Healthy, NAFLD (Non-Alcoholic Fatty Liver Disease), NASH (Non-Alcoholic Steatohepatitis)
- Trial name
- NCT02690792
- Testing
- NAFLD/NASH - Vitamin E
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jeffrey Browning
Osteoarthritis
Vitamin E-Diffused Highly Cross-Linked Polyethylene Liner
Vitamin E incorporated highly cross linked polyethylene (E-XLPE) was developed to increase oxidative resistance of highly cross-linked polyethylene (XLPE) without affecting mechanical properties.
- Trial name
- NCT02801019
- Testing
- E-poly, ArComXL
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Nutrition Poor, Micronutrient Deficiency
Role of Hazelnut Consumption in Improving Micronutrient Status in Older Adults
With advancing age, older adults are susceptible to vitamin and mineral deficiencies for a variety of reasons. Nutrient-dense food sources of vitamin E and other key vitamins and minerals, like hazelnuts, may offer a simple means…
- Conditions
- Nutrition Poor, Micronutrient Deficiency, Aging
- Trial name
- NCT03485989
- Testing
- Hazelnuts
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Asthma
Safety Study of a Vitamin E Supplement in Normal Volunteers and Those With Both Allergy and Asthma
Gamma tocopherol (gt) is a naturally occurring form of vitamin E that is found in many foods, and is also commercially available as a vitamin supplement.
- Trial name
- NCT00386178
- Testing
- Vitamin E supplement rich in gamma tocopherol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Mono Infection
Nonalcoholic Steatohepatitis in HIV Mono-infection: Exploring Non-invasive Methods for Diagnosis and the Therapeutic Role of Vitamin E
Effective combination antiretroviral therapy (cART) has resulted in a dramatic reduction in AIDS mortality. Over the last decade, the proportion of deaths caused by liver-related etiologies, including co-infection with hepatitis…
- Trial name
- NCT03988725
- Testing
- Vitamin E
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type2 Diabetes Mellitus
n-3 Fatty Acid Effects in T2DM After Acute High Intensity Exercise
The aim of this study was to verify the effect of a combined supplementation [n-3 PUFA (known to induce anti-inflammatory effects) plus vitamin E (known for its antioxidant properties)] on lipidic, glycemic, redox status and…
- Trial name
- NCT03182712
- Testing
- n-3 PUFA Group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Rio Grande do Sul
Colorectal Cancer Metastatic
Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer
This double blind, randomized phase II trial will investigate whether the addition of tocotrienol will improve the effect and lower the toxicity of standard chemotherapy and bevacizumab.
- Trial name
- Toco-CoR (NCT04245865)
- Testing
- Fluorouracil, Calcium folinate, Oxaliplatin
- Where
- Denmark
- Volunteers
- 83 people
- Sponsor
- Vejle Hospital
Post Kala Azar Dermal Leishmaniasis
Miltefosine for Children With PKDL
Hypothesis: Primary hypothesis: 1. Oral treatment with Miltefosine in children with PKDL at allometric daily dose (based on body weight and height) for 12 weeks is safe with a cure rate of ≥95%. Secondary hypothesis: 2.
- Trial name
- NCT02193022
- Testing
- Miltefosine
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Chronic Arsenic Poisoning
Effect of Vitamin E on Skin Aerobic Bacteria in Palmar Arsenical Keratosis
This study will be conducted to observe any change in aerobic bacterial pattern on the skin of arsenicosis patients before and after administration of vitamin E (200 IU) capsules.
- Trial name
- NCT02468518
- Testing
- Vitamin E capsule
- Where
- Bangladesh
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh