Clinical trials: Vitamin Supplementation
Diabetes Mellitus Type 2, Vitamin D Deficiency
Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
Background and Objectives : The presence of vitamin D deficiency in patients with type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular disease (CVD).
- Trial name
- DIMENSION (NCT01741181)
- Testing
- Vitamin D supplementation
- Where
- Singapore
- Volunteers
- 64 people
- Sponsor
- Tan Tock Seng Hospital
Type 2 Diabetes Mellitus
Can Vitamin D Supplementation Prevent Type 2 Diabetes?
The aim of this study is to determine whether vitamin D supplementation in overweight/obese individuals with vitamin D deficiency can improve insulin secretion and/or insulin resistance by decreasing subclinical inflammation.
- Trial name
- NCT02112721
- Testing
- Vitamin D
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Monash University
Vitamin D Deficiency
Improving Functionality in Older People
The study will examine if overall functionality of older adults with Vitamin D insufficiency can be improved by optimal Vitamin D replacement over a period of approximately one year.
- Trial name
- NCT03611049
- Testing
- High dose Vitamin D3, Low dose Vitamin D3
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Obesity
The Effect of Vitamin A Supplementation on Cytokine Profile in Obesity
In this double blind placebo controlled trial,cytokine secretion of CD4+ T-cells after 4 month supplementation of vitamin A will be compared with placebo intaking group.
- Trial name
- NCT01405352
- Testing
- Vitamin A
- Where
- Iran
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Healthy
Vitamin B12 Biomarker Responses to Supplementation
The aim of the study is to investigate the response of recognized biomarkers of vitamin B12 status to intervention with supplemental vitamin B12 at doses within and beyond the range of typical dietary intakes in younger and older…
- Trial name
- NCT04731948
- Testing
- Folic Acid, 2 µg Vitamin B12, 10 µg Vitamin B12
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Depression
B Vitamins in MTHFR Positive Patients With Major Depression: A Post Hoc Analysis of Findings
A randomized double-blind placebo controlled study of reduced B vitamins in patients with major depression who were positive for one or both of the common MTHFR polymorphisms was conducted between 8/1/2014 and 4/3/2015.
- Trial name
- BVMD (NCT02709668)
- Testing
- Enlyte
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- High Point Regional Health Systems
Calcium and Vitamin D Deficiencies
Calcichew D3 Preference Study in Participants Eligible for Calcium and Vitamin D Supplementation.
The purpose of this study is to compare the preference of Calcichew D3 500/400 (containing 500 mg calcium and 400 IU of vitamin D) with Adcal-D3 600/400 (containing 600 mg of calcium and 400 IU of vitamin D) in Test Group 1, and…
- Trial name
- NCT02457247
- Testing
- Calcichew D3, Adcal-D3, Kalcipos-D
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 276 people
- Sponsor
- Takeda
Cutaneous Malignant Melanoma
Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome
To assess whether vitamin D supplementation after surgery of a first cutaneous malignant melanoma protects against relapse of the disease.
- Trial name
- ViDMe (NCT01748448)
- Testing
- Vitamin D
- Where
- 4 sites in Belgium, Hungary
- Volunteers
- 436 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heart Failure, Acidosis, Lactic
Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery
The objective of this study is to determine whether preoperative parenteral thiamin supplementation does prevent the intra and early postoperative increase of lactate and whether this effect is related to the extent of thiamine…
- Conditions
- Heart Failure, Acidosis, Lactic, Thiamine Deficiency
- Trial name
- NCT01524315
- Testing
- Vitamin B1-ratiopharm
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Asthma in Children
Vitamin A and D Intake in Pregnancy, Infant Supplementation and Asthma Development
The objective of this study is to investigate if maternal intake of vitamins A and D from food and dietary supplements during pregnancy, and infant supplementation with these vitamins, are associated with development of asthma in…
- Trial name
- NCT03197233
- Testing
- Maternal vitamin A and D intake during pregnancy
- Volunteers
- 61,676 people
- Sponsor
- Norwegian Institute of Public Health
Active Rheumatoid Arthritis
Vitamin D Effect in Rheumatoid Arthritis.
Regulatory T (Tregs) cells play an important role in the maintenance of immunological tolerance. It decrease in the peripheral blood of rheumatoid arthritis patients.
- Trial name
- NCT04472481
- Testing
- Ergocalciferol 1.25 mg tablet
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Infertility
Effect of Vitamin D Supplementation in Live Birth Rate of in Vitro Fertilization Outcome
This is a randomized-controlled trial evaluating the effect of the use of vitamin D supplementation on the live birth rate in women undergoing in vitro fertilization (IVF).
- Trial name
- NCT04547530
- Testing
- Vitamin D
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,150 people
- Sponsor
- The University of Hong Kong
COVID-19
Vitamin D Supplementation and Clinical Improvement in COVID-19
Background and objective Vitamin D is important as the interaction between vitamin D and its receptors at the immune cells stimulates innate and adaptive immunity.
- Trial name
- NCT05126602
- Testing
- Vitamin D3 10000 IU, Vitamin D3 1000 IU
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Bumi Herman
Helicobacter Pylori Infection
Role of Vitamin D Supplementation as an Adjuvant Therapy inTreatment of Helicobacter Pylori in Children
To study the efficacy of vitamin D in conjunction with Helicobacter pylori treatment in children in eradication of helicobacter pylori.
- Trial name
- NCT05879237
- Testing
- Vitamin D3, Helicobacter pylori triple therapy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Type 2 Diabetes, Vitamin B12 Deficiency
Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients
Increased plasma homocysteine level is associated with macroangiopathy and nephropathy in type 2 diabetes. Also increased levels of serum homocysteine are associated with microalbuminuria which is associated with increased…
- Conditions
- Type 2 Diabetes, Vitamin B12 Deficiency, Hyperhomocysteinemia
- Trial name
- NCT02540642
- Testing
- METHYLCOBALAMIN 500 micrograms
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Smt. Kashibai Navale Medical College and General Hospital
Gynecologic Cancer
PROtein, Leucine and Vitamin D Supplementation In Patients With GYnecologic Cancer Receiving Platinum-based Chemotherapy
Open clinical trial addressing the effect of a nutritional support based on whey proteins, leucine and vitamin D on muscle mass and multiple anticancer treatment-related endpoints in patients with gynecologic cancer receiving…
- Trial name
- PRODIGY-1 (NCT06087783)
- Testing
- Experimental product - Fortifit® Powder, Standard of care
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Type 2 Diabetes
Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids…
- Trial name
- NCT01633177
- Testing
- Vitamin D3, Omega-3 fatty acid (fish oil)
- Where
- United States
- Volunteers
- 22,220 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypovitaminosis D, Insulin Resistance
Hypovitaminosis D : A Link Between Bone/Mineral and Fat/Fuel Metabolism
The optimal dose of vitamin D needed to optimize beneficial effects on musculoskeletal outcomes remains to be defined. Equally unclear is the impact of vitamin D on fuel metabolism and insulin sensitivity in human subjects.
- Conditions
- Hypovitaminosis D, Insulin Resistance, Obesity, Osteoporosis
- Trial name
- GEHF-VitD (NCT01315366)
- Testing
- Euro D and Ci-CalD, Euro D, Ci-CalD
- Where
- Lebanon
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Sarcopenia, Hip Fracture
Hyperprotein Nutritional Intervention in Elderly Patients With Hip Fracture and Sarcopenia
1. RATIONALE The unique characteristic of our study lies in the attempt to reverse the functional impairment experienced by sarcopenic patients with hip fracture using nutritional intervention.
- Trial name
- HIPERPROT (NCT01404195)
- Testing
- Ensure Plus Advance
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Migraine Headache, Arterial Stiffness
Vitamin K2 Supplementation in Adult Episodic Migraine
Migraine is a debilitating illness and a major cause of disability in the world. It is highly prevalent, especially among women.
- Conditions
- Migraine Headache, Arterial Stiffness, Vitamin K Deficiency
- Trial name
- ViKEM (NCT05943457)
- Testing
- Vitamin K2 or menaquinone-7
- Where
- Lebanon
- Volunteers
- 160 people
- Sponsor
- Sola Aoun Bahous, M.D. Ph.D.