Clinical trials: Vitreoretinal Surgery
Ophthalmological Virtual Surgery Training
Virtual Surgery: Construction of a Training Program and Analysis of Significant Factors for Operating Performance
Operations in the retina and removal of the vitreous (vitrectomy) is a type of operation where the surgeon requires much training and where there is an increased risk of operative complications in the early stage.
- Trial name
- NCT02559661
- Testing
- Training on a virtual simulator in eye surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
Vitreoretinal surgery for epiretinal proliferation tractional retinal detachment associated with proliferative diabetic retinopathy (PDR) is often complicated by hemorrhage from fibrovascular tissue.
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Trial name
- NCT00548197
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Macular Hole, Visual Acuity
Combined Versus Successive Macular Hole and Cataract Surgery
The purpose of this study is to compare functional and anatomical results of a combined surgery and two time surgery for macular hole and cataract extraction in one hundred and twenty patients (120 eyes) with idiopathic Macular…
- Trial name
- NCT01069029
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Vitreoretinal Disease
Trends of Vitreoretinal Surgery in Children
Purpose: We determined the incidence, etiology, and longitudinal trends of vitreoretinal diseases necessitating pars plana vitrectomy (PPV) in the pediatric and adolescent population.
- Trial name
- NCT06123923
- Testing
- no intervention
- Where
- South Korea
- Volunteers
- 3,509 people
- Sponsor
- Seoul National University Hospital
Diabetic Retinopathy
Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy
To investigate the feasibility and advantages of using perfluorocarbon liquid (PCL) perfusion to remove vitreous during suction-cutting vitrectomy using a dual, dynamic drive (3D)technology.
- Trial name
- NCT00407108
- Testing
- Vitrectomy
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Macular Hole
Air Tamponade in Macular Hole Surgery
Macular hole is a hole formation which takes place in the center of the retina. Such a hole needs surgical steps in order to close. Closure of the macular hole will lead to a substantially improvement of vision in most cases.
- Trial name
- NCT01680068
- Testing
- Pars plana vitrectomy and postoperative air tamponade
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Helse Stavanger HF
Eye Injury Trauma
Adjunctive Steroid Combination in Ocular Trauma (ASCOT) Study
Eye trauma is a leading cause of blindness and visual impairment. Penetrating injuries of the eye are more likely to result in poor vision and the main cause of this is a scarring response on the retina (proliferative…
- Trial name
- ASCOT (NCT02873026)
- Testing
- Triamcinolone Acetonide
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Macular Holes, Epiretinal Membrane
Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies
The aim of the study is to identify morphological and functional biomarkers of post-operative recovery after vitreoretinal surgery, using decisional support systems (DSS), based on multimodal big-data analysis by means of machine…
- Conditions
- Macular Holes, Epiretinal Membrane, Retinal Detachment, Macular Dystrophies
- Trial name
- MICAI (NCT05747144)
- Testing
- Biometry, Retinography (Color) + Autofluorescence (AF), OCT B-scan and OCT angiography (OCTA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetic Retinopathy, Retinal Neovascularisation
Ranibizumab in Diabetic Vitrectomy. A Prospective, Randomised Controlled Trial of Ranibizumab Pre-treatment in Diabetic Vitrectomy - a Pilot Study
This study will evaluate the effect of ranibizumab on patients undergoing vitrectomy surgery for the complications of diabetic retinopathy.
- Trial name
- RaDiVit (NCT01306981)
- Testing
- Ranibizumab, Saline
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Rhegmatogenous Retinal Detachment
Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal
Background and study aims The retina is the layer at the back of the eye that allows us to see. Sometimes, it can detach from the wall of the eye, causing a condition called rhegmatogenous retinal detachment (RRD), which leads to…
- Trial name
- COMBAT (NCT06997874)
- Testing
- Phacovitrectomy, Vitrectomy
- Where
- 30 sites in United Kingdom
- Volunteers
- 276 people
- Sponsor
- Queen's University, Belfast
Surgery
Use of Fibrin Glue in Vitreoretinalsurgery
To study the Safety and Efficacy of the use of fibrin glue in vitreoretinal surgery
- Trial name
- fibringlue (NCT01022164)
- Testing
- fibrin glue
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Macular Holes
Air Tamponade in Macular Holes < 400 μm
Macular hole is a hole formation which takes place in the center of the retina. Such a hole needs surgical steps in order to close. Closure of the macular hole will lead to a substantially improvement of vision in most cases.
- Trial name
- NCT02028481
- Testing
- Postoperative air tamponade
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- Helse Stavanger HF
Subtenon Anesthesia
Subtenon Block Combined With General Anesthesia for Vitreoretinal Surgery
To evaluate the effects of subtenon block (SB) as an adjunct to general anaesthesia on postoperative pain, oculocardiac reflex and postoperative nausea and vomiting for vitreoretinal surgery.
- Trial name
- NCT02282774
- Testing
- 2% lidocaine and 0.5% bupivacaine
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Saud University
Macular Pucker, Macular Hole
Membrane Blue Versus Infracyanine Green
To compare possible toxicities of membrane blue and infracyanine green in vivo by macular function and peripheral visual field.
- Trial name
- NCT00555269
- Volunteers
- 30 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Vitreoretinal Disease With or Without Cataracts
Next Generation Cataract and Vitreoretinal Surgery Study
The purpose of this study is to obtain device-specific safety and performance clinical data to support marketability in Europe and to collect formal user feedback.
- Trial name
- NCT06165744
- Testing
- UNITY Vitreoretinal Cataract System, Posterior segment surgery in the operating room with or without simultaneous cataract surgery
- Where
- 5 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Vitreoretinal Surgeries, Local Anesthesia
Comparative Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries
The majority of patients undergoing ophthalmic surgeries are elderly, with multiple chronic diseases, with increased risk of morbidity and mortality under general anesthesia.
- Trial name
- NCT06501352
- Testing
- Dexmedetomidine, Neostigmine, Saline
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Ain Shams University
Intraocular Pressure
Evaluation of Intraocular Pressure Following a Vitreoretinal Surgery Using Goldmann Applanation Tonometry, Icare and Accupen
The goal of this prospective controlled study is to measure the reliability of two intraocular pressure (IOP)-measuring instruments in comparison to the gold standard, Goldmann applanation tonometry (GAT) following vitreo-retinal…
- Trial name
- NCT06522867
- Testing
- Intraocular pressure measure
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- CHU de Quebec-Universite Laval
Vitreoretinal Surgery, Ocular Inflammation
Dextenza in the Post-op Management of Vitreoretinal Surgeries
This study will assess the control of inflammation at days 1, 7, 14, and 21 days following the vitreoretinal surgical procedure analyzing two randomized study arms: Intracanalicular dexamethasone insert group or topical steroid…
- Conditions
- Vitreoretinal Surgery, Ocular Inflammation, Post-operative Pain, Post-Operative Inflammation
- Trial name
- NCT04371445
- Testing
- Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Vitreoretinal Surgery, Cognitive Function Abnormal
The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients
The investigators measured changes in cerebral oxygen saturation (rSO2) and MMSE scores after retrobulbar block performed with levobupivacaine and lidocaine in patients undergoing vitreoretinal surgery.A total of 66 patients over…
- Conditions
- Vitreoretinal Surgery, Cognitive Function Abnormal, Intraoperative Monitoring
- Trial name
- NCT03189329
- Testing
- 2% lidocaine hydrochloride, 0.5% levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cengiz KAYA
Vitreoretinal Surgery
Foldable Capsular Vitreous Body Implantation Study
This study is intended to evaluate the clinical usefulness of the FCVB in its on-label use, but in a different racial type than studies till now (Asians only).
- Trial name
- FCVB (NCT03390244)
- Testing
- Foldable Capsular Vitreous Body Implant
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven