Clinical trials: Vocal Cord Disease
Neurological Disorder, Ultrasound
Ultrasound to Detect Vocal Fold Movement in Neurological Disease
This study aims to investigate the accuracy and viability of transcutaneous laryngeal ultrasound (US) in detecting impairments of vocal fold movement in people with neurological disorders.
- Conditions
- Neurological Disorder, Ultrasound, Vocal Fold Movement
- Trial name
- NCT05493397
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Vocal Cord Paresis, Acquired Vocal Cord Palsy
The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery
Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients.
- Trial name
- NCT02996526
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- University of Manitoba
Larynx Cancer Stage I, Glottic Carcinoma
Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer
The primary objective of this prospective randomized clinical trial is to assess non inferiority in terms of local control achieved with single vocal cord hypofractionated radiotherapy compared to standard of care whole laryngeal…
- Trial name
- VC-Larynx (NCT05679856)
- Testing
- Hypofractionated single vocal cord irradiation, Whole laryngeal radiotherapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute, Egypt
Presbylarynx, Aspiration
Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders.
- Conditions
- Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus
- Trial name
- NCT06078527
- Testing
- Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Otorhinolaryngologic Diseases
Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a latissimus dorsi or pectoral flap, to…
- Trial name
- NCT00213837
- Testing
- Mandibular prosthesis made of a new highly biointegratable material
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Strasbourg, France
Unilateral Vocal Cord Paralysis, Vocal Cord Atrophy
Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery
The goal of this observational study is to learn about the long-term outcomes of Laryngeal Framework Surgery (LFS) in patients with Unilateral Vocal Fold Paralysis (UVFP) or Vocal Fold Atrophy (VFA).
- Trial name
- NCT07579364
- Testing
- Laryngeal Framework Surgery
- Where
- 10 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Francisco
Unilateral Vocal Cord Paralysis
Non-phonatory Exercises in Patients with Unilateral Vocal Fold Paralysis Post-thyroidectomy
Thyroidectomy is the most common iatrogenic cause of vocal fold paralysis. Patients complain of hoarseness caused by incomplete glottic closure and have effort to raise vocal intensity with consequent elevation of the larynx…
- Trial name
- ENFP (NCT05963165)
- Testing
- Non-phonatory exercises
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Neurogenic Dysphonia, Neurogenic Dysphagia
Neurogenic Dysphonia/Dysphagia Registry
The Neurogenic Dysphonia/Dysphagia Registry is designed to be purely observational (i.e. non-interventional, exploratory). Patient data collected from the registry is expected to be consistent with any information which can be…
- Trial name
- StrongVoice (NCT02493491)
- Where
- 12 sites in United States
- Volunteers
- 146 people
- Sponsor
- Merz North America, Inc.
Vocal Cord Paralysis, Phonasthenia
A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Larynx performs important functions of the aero-digestive tract, it has vital role in control of breathing, phonation, deglutition and protection of lower respiratory tract from aspiration.
- Conditions
- Vocal Cord Paralysis, Phonasthenia, Presbylarynges, Idiopathic Vocal Cord Paralysis
- Trial name
- NCT04458818
- Testing
- Prolene Mesh Vocal Cord Medialization Implant
- Where
- Pakistan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Muhammad Rashid
Laryngeal Paralysis
Very Long Term VHI Voice Outcome After MTIS
Long term assesment of voice outcome after Montgomery Thyroplastie by performing a Survey of operated patients using the voice handicap index scale
- Trial name
- NCT02969993
- Testing
- Questionnaires
- Where
- 3 sites in Belgium, Spain
- Volunteers
- 53 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Laryngomalacia, Laryngospasm
Manual Valsalva Maneuver As a Preventive Measure of Postoperative Laryngospasm in Laryngomalacia Cases Undergoing Supraglottoplasty
We hypothesized that manual valsalva maneuver prevent incidence of postoperative laryngospasm after supraglottoplasty for cases of congenital laryngomalacia.
- Trial name
- NCT06627660
- Testing
- Valsalva maneuver
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Laryngeal Disease, Spastic Dysphonia
Characteristics of Idiopathic Familial Voice Disorders
The purpose the study is to determine the genetic causes of specific voice disorders that run in families. Researchers are particularly interested in two conditions; 1. Spasmodic dysphonia 2.
- Conditions
- Laryngeal Disease, Spastic Dysphonia, Voice Disorder
- Trial name
- NCT00001552
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Larynx, Obstruction
CLE During Exercise Testing in Asthma
The purpose is to assess visualize the level of laryngeal obstruction and vocal cord dysfunction and to obtain more information on causes for dyspnea in asthma and severe asthma and to assess safety of CLE in patients with asthma…
- Conditions
- Larynx, Obstruction, Vocal Cord Dysfunction
- Trial name
- CLEtesting (NCT04168671)
- Testing
- Continuous laryngoscopy during exercise test
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Recurrent Paralysis of Vocal Cords
Efficacy of Oral Corticosteroid Therapy in Recurrent Paralyzes After Thyroidectomy
Thyroidectomy is a common surgical procedure in France. Recurrent paralysis is one of the main complications. Oral corticosteroid therapy are frequently used at a dosage of 1mg/kg for seven days, in case of recurrent paralysis to…
- Trial name
- NCT03553342
- Testing
- Corticoids
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Poitiers University Hospital
Emergence Agitation, Vocal Cord Polyps
Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension Laryngoscopy
This is a single-center, prospective, single-blinded, randomized controlled trial conducted at The First Hospital of Jilin University.
- Trial name
- NCT07880938
- Testing
- Dexmedetomidin, Esketamine
- Where
- China
- Volunteers
- 134 people
- Sponsor
- The First Hospital of Jilin University
Disorder of Vocal Cord
Exercise-induced Paradoxical Vocal Fold Motion Disorder: Clinical Features and Potential Mechanisms
Exercise-induced paradoxical vocal fold motion disorder (E-PVFMD) - which severely impacts the lives of up to 1 million adolescents in the U.S.
- Trial name
- NCT02947009
- Testing
- Diagnostic Study
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Pittsburgh
Voice Change, Hypocalcemia
The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and Hypocalcaemia
Thyroidectomy is a standard procedure for benign and malignant pathologies of the thyroid gland. Each year, some 100 total thyroidectomies are performed in Kowloon East Cluster, Hospital Authority, Hong Kong.
- Trial name
- NCT05732883
- Testing
- Dexamethasone, Normal saline
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Vocal Cord Paralysis
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis
Vocal cord paralysis is a common cause of congenital stridor and airway obstruction. In this study we plan to identify the genetic locus of the genes in two extended families who suffer of the disease.
- Trial name
- NCT00382369
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Hadassah Medical Organization
Cough, Laryngospasm
Benefits of Exchanging a Double Lumen Tube to a Proseal Laryngeal Mask or a Single Lumen Tube After a Thoracic Surgery
The purpose of this study is to determine whether exchange of the double lumen tube before emergence with a laryngeal mask airway (Proseal) or a tracheal tube will reduce cough at emergence.
- Conditions
- Cough, Laryngospasm, Apnea, Desaturation
- Trial name
- NCT00925613
- Testing
- LMA Proseal, Tracheal tube
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Dyspnea
Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)
Vocal cord dysfunction is a rare clinical picture. It is labeled as a sudden and threatening dyspnea. Patients with VCD may also present cough, hoarseness, wheezing, and chest tightness, but an inspiratory stridor is the most…
- Trial name
- VCD (NCT00906867)
- Testing
- Methacholine challenge testing, Rhino-laryngoscopy
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Johann Wolfgang Goethe University Hospital