Clinical trials: Vocal Cord Palsy
Vocal Cord Paresis, Acquired Vocal Cord Palsy
The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery
Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients.
- Trial name
- NCT02996526
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- University of Manitoba
Vocal Cord Paralysis, Recurrent Laryngeal Nerve
Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery
Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates.
- Trial name
- NCT03634956
- Testing
- Group B. Sugammadex sodium-IONM
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Post-Thyroidectomy Dysphonia
Effects of Therapeutic Exercise With and Without Nerve Stimulation on Dysphonia in Post Thyroidectomy Patients
This clinical trial evaluates rehabilitation strategies for post-thyroidectomy dysphonia. Voice impairment is a frequent complication following thyroid surgery. It often occurs even without direct laryngeal nerve transection.
- Trial name
- NCT07811154
- Testing
- therapeutic exercise, therapeutic exercise + transcutaneous nerve stimulation
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Unilateral Vocal Cord Paralysis, Unilateral Vocal Cord Paresis
Recurrent Laryngeal Nerve Monitoring During Pediatric Aerodigestive Tract and Cardiac Surgery
This research studies whether a device used during surgery can help doctors better protect the nerve that moves a child's vocal cords. Damage to this nerve can affect speaking, swallowing, and sometimes breathing.
- Trial name
- NCT07604623
- Testing
- Intraoperative laryngeal nerve monitor
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malignant Neoplasm of Thyroid Gland
Trial on Intraoperative Neuromonitoring (IONM) in Thyroid Cancer Surgery.
Scientific objectives: Primary objective: To assess if the use of IONM can decrease the rates of temporary RLN palsy after thyroid cancer surgery Secondary objectives: To assess if the use of IONM can decrease permanent RLN palsy…
- Trial name
- ACTION (NCT04842994)
- Testing
- IONM tube
- Where
- India
- Volunteers
- 448 people
- Sponsor
- Tata Memorial Hospital
Unilateral Vocal Cord Paralysis
The Function of Cricothyroid Muscle and Its Impaction on Mandarin Lexical Tones in Unilateral Vocal Fold Paralysis
Mandarin Chinese phonemically distinguishes four tones, with Tone 1 having high-level pitch, Tone 2 high-rising pitch, Tone 3 low-dipping pitch, and Tone 4 high-falling pitch The same segmental context carries different meanings…
- Trial name
- NCT02184377
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Evaluation of the Role of IONM in Minimally Invasive Parathyroidectomy Performed for Solitary Parathyroid Adenoma
Evaluation of the Role of Intraoperative Neuromonitoring(IONM) in Patients Undergoing Parathyroid Surgery for Solitary Parathyroid Adenoma
Aim: Intraoperative neuromonitoring (IONM) is frequently used in cases of primary hyperparathyroidism (pHPT); however, its role in cases of solitary parathyroid adenoma has not been clearly defined, and differing opinions exist…
- Trial name
- NCT07836335
- Testing
- INTRAOPERATIVE NEUROMONITORING
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Katip Celebi University
Vocal Fold Palsy
Voice Telerehabilitation
The aim of the study was to determine functional results of telerehabilitation (TR) in subjects affected by iatrogenic unilateral vocal fold paralysis (UVFP) during the COVID-19 pandemic outbreak.
- Trial name
- NCT05747859
- Testing
- teletherapy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy
Predisection Risk Factors for Vocal Cord Palsy After Total Thyroid Surgery
In patients undergoing total thyroidectomy, intraoperative nerve monitoring according to the International Standards Guideline Statement may detect nerves more susceptible to injury.
- Conditions
- Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy, Neuromonitoring in Thyroid Surgery
- Trial name
- NCT04986592
- Volunteers
- 106 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pain, Acute, Vocal Fold Polyp
Patient Augmented Reality and Vibratory Array Otorhinolaryngology Procedures
In-office procedures (IOPs) are a cost-effective, and safe alternative to many operating room procedure, with benefits such as reduced anesthesia risk.
- Conditions
- Pain, Acute, Vocal Fold Polyp, Vocal Cord Paralysis, Laryngeal Neoplasms
- Trial name
- PARVA (NCT06227039)
- Testing
- Vibroacoustic stimulation on, Augmented Reality on, Vibroacoustic stimulation off
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Thyroid Diseases, Recurrent Laryngeal Nerve Injury
Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery
Intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroidectomy is most commonly performed with surface electrodes embedded in the endotracheal tube (ETT).
- Conditions
- Thyroid Diseases, Recurrent Laryngeal Nerve Injury, Vocal Cord Paralysis, Thyroid Nodule
- Trial name
- TRANSCOMP (NCT07902349)
- Testing
- Transcartilage needle electrode recording, Endotracheal tube surface electrode recording
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Unilateral Vocal Cord Paralysis
Non-phonatory Exercises in Patients with Unilateral Vocal Fold Paralysis Post-thyroidectomy
Thyroidectomy is the most common iatrogenic cause of vocal fold paralysis. Patients complain of hoarseness caused by incomplete glottic closure and have effort to raise vocal intensity with consequent elevation of the larynx…
- Trial name
- ENFP (NCT05963165)
- Testing
- Non-phonatory exercises
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Herpes Esophagitis, Vocal Fold Palsy
Unusual Clinical Findings of Herpes Esophagitis
Herpes esophagitis presents a clinical diagnostic challenge. The investigators report the first case of herpes esophagitis presenting as vocal fold palsy in an immunocompetent host.
- Trial name
- NCT01501526
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Recurrent Laryngeal Nerve Palsy, Postoperative Dysphonia
Post Thyroidectomy Echographic Method for Study of Vocal Fold Motion
One of the major risks of endocrine surgery is recurrent nerve palsy (RNP), leading to vocal folds (VF) immobility. It happens in 5% of cases, leading to high morbidity: dysphonia, aspirations, impossibility to work.
- Trial name
- VOCALE (NCT03976011)
- Testing
- Transcutaneous Laryngeal Ultrasonography
- Where
- 5 sites in France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vocal Fold Palsy
Allograft Adipose Injectable for Vocal Fold Paralysis
Renuva is allograft adipose matrix commonly used as a filler in cosmetic procedures. The investigators are studying this material as an injectable in the vocal fold to treat glottic insufficiency.
- Trial name
- NCT04700566
- Testing
- Renuva Allograft Adipose Matrix
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Bilateral Vocal Cord Paralysis
Performance of the SPIRION Laryngeal Pacemaker in BVFP Patients Without Glottal Enlargement
The goal of this clinical investigation is to learn about the use of a novel medical device, the SPIRION Laryngeal Pacemaker, in patients suffering from bilateral vocal fold paralysis (BVFP).
- Trial name
- NCT06007170
- Testing
- SPIRION Laryngeal Pacemaker System Implantation and follow-up
- Where
- 6 sites in Austria, Germany
- Volunteers
- 20 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Bilateral Vocal Cord Paralysis
Performance of the SPIRION Laryngeal Pacemaker in BVFP Patients With Single-sided Glottal Enlargement
The goal of this clinical investigation is to learn about the use of a novel medical device, the SPIRION Laryngeal Pacemaker, in patients suffering from bilateral vocal fold paralysis (BVFP) and who have had at least one related…
- Trial name
- NCT06007144
- Testing
- SPIRION Laryngeal Pacemaker System Implantation and follow-up
- Where
- 6 sites in Austria, Germany
- Volunteers
- 10 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Vocal Fold Palsy, Vocal Cord Paralysis
A Histological Study Evaluating Silk Voice and Crosslinked Hyaluronic Acid
The primary study goal is to evaluate the histological characteristic of Silk Voice to evaluate the potential for Silk Voice to deliver long-term results to patients.
- Conditions
- Vocal Fold Palsy, Vocal Cord Paralysis, Vocal Cord Atrophy
- Trial name
- NCT04315415
- Testing
- Silk Voice
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sofregen Medical, Inc.
Laryngeal Carcinoma, Bilateral Vocal Cord Paresis
Thulium Contact Laser of Laryngotracheal Stenosis
The purpose of the study is to compare results of the treatment of tumorous and non-tumorous laryngotracheal stenosis using thulium contact laser versus carbon dioxide laser used in the past.
- Conditions
- Laryngeal Carcinoma, Bilateral Vocal Cord Paresis, Subglottic Stenosis
- Trial name
- NCT02587546
- Testing
- laryngeal carcinoma, bilateral vocal cord paralysis, subglottic stenosis
- Where
- Czechia
- Volunteers
- 31 people
- Sponsor
- University Hospital Ostrava