Clinical trials: Voice, open to volunteers
Presbyphonia, Deep Cervical Muscles
THE EFFECT OF POSTURAL ALİGNMENT AND DEEP CERVICAL MUSCLE TRAINING ON VOICE FUNCTION IN OLDER ADULTS WITH PRESBYPHONIA
This study examined whether posture exercises and deep neck muscle training can improve voice quality in older adults with presbyphonia, an age-related voice disorder.
- Trial name
- PRESBYPHONIA (NCT07771114)
- Testing
- Neck Stabilization Exercises Group, Control Group
- Volunteers
- 90 people
- Sponsor
- Suleyman Demirel University
Parkinson Disease, Idiopathic
The Impact of Deep Brain Stimulation on Speech and Swallow Function in Parkinson Disease
Nearly one-million people in North America are now living with Parkinson's disease (PD), and that number is projected to rise to nearly 1.2 million by 2030.
- Trial name
- NCT07026734
- Testing
- Deep brain stimulation surgery - GPi, Deep Brain Stimulation Surgery - STN
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Cancer, Solid Tumor Cancer
Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer
This study entails enrolling participants that have been diagnosed with cancer to Olivia, a commercially available AI-enabled personal health platform developed by Tempus.
- Conditions
- Cancer, Solid Tumor Cancer, Pediatric Acute Myeloid Leukemia, Hematologic Malignancies
- Trial name
- ONCO-OLIVIA (NCT07756034)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tempus AI
Overactive Bladder (OAB), Overactive Bladder Syndrome
Real-world Experiences and Voices Exploring the Actual Lived Burden of OAB: A Mixed-methods Multi-country PROMs Study on OAB Patients' Quality of Life
The main goal is to understand what it is truly like to live with OAB from the patient's perspective, including how it affects: daily activities, emotional wellbeing and mental health, social life and relationships, work and…
- Trial name
- REVEAL-OAB (NCT07545148)
- Volunteers
- 2,000 people
- Sponsor
- European Association of Urology Research Foundation
Sepsis
Call for Life Sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-attributable mortality in sub-Saharan Africa (sSA) is high, with in-hospital mortality in some settings approaching 40%.
- Trial name
- C4L-Sepsis (NCT07407868)
- Testing
- Interactive Voice Response system-Call for life IVR
- Where
- 2 sites in Uganda
- Volunteers
- 1,410 people
- Sponsor
- Makerere University
Atrophy of Vocal Cord, Presbyphonia
PhoRTE® Therapy Efficacy: In-Person Versus Telehealth
This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems.
- Conditions
- Atrophy of Vocal Cord, Presbyphonia, Dysphonia, Glottic Insufficiency
- Trial name
- NCT06934265
- Testing
- exuberant voice therapy
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Burnout, Burnout, Healthcare Workers
Evaluation of Speech and Voice Biomarkers in Association With Burnout
This project aims to explore how speech patterns and voice characteristics can be used to detect signs of burnout and stress in physicians.
- Trial name
- Voice-B (NCT07780812)
- Testing
- Calmigo
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Minneapolis Heart Institute Foundation
Speech Disorders, Speech Dysfunction
Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy Patients (UC Davis)
To perform a multi-site prospective study assessing, both subjectively and objectively, the gender disparities in speech outcomes of patients using TEP after total laryngectomy.
- Conditions
- Speech Disorders, Speech Dysfunction, Laryngectomy; Status, Tracheoesophageal Prosthesis
- Trial name
- NCT05489965
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Heart Failure
Artificial Voice Analysis and Telemonitoring for Heart Failure. A Feasibility Study
Heart failure is a serious condition and a major reason why older adults are admitted to the hospital. Even after going home, many patients struggle to get the follow-up care they need, leading to high rates of return to the…
- Trial name
- AVATAR-HF (NCT07664748)
- Testing
- AVATAR-SC, Levosimendan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Niguarda Hospital
Postoperative Dysphonia
Longitudinal Non-invasive Analysis of VOCAle Cord Function Based on Trans-laryngeal Ultrasound Acquisitions and Voice Recordings
The main objective of VOCALISE study is to propose a new approach allowing a better characterization of postoperative dysphonia.
- Trial name
- VOCALISE (NCT06776393)
- Testing
- ultrasound
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tetraplegia/Tetraparesis, Quadriplegia
VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration
The VOICE Study is an early feasibility study to evaluate the initial clinical safety and efficacy of the N1 and R1 Systems device design concept in providing an ability to communicate.
- Conditions
- Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis
- Trial name
- NCT07224256
- Testing
- N1 Implant, R1 Robot
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Neuralink Corp
Parkinson's Disease (PD)
Efficacy of LSVT-LOUD Therapy on Voice, Speech, and Quality of Life in Parkinson's Disease
Parkinson's disease often causes speech and voice impairments, such as reduced vocal loudness and decreased speech intelligibility, which significantly impact the quality of life for patients and their families.
- Trial name
- NCT07730073
- Testing
- LSVT-LOUD Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Atlas University
Schizophrenia Disorder, Schizoaffecitve Disorder
DecNef for Auditory Verbal Hallucinations (AVH) in Schizophrenia
The purpose of this study is to learn whether a research neurofeedback training approach done during MRI scans may help reduce hallucinations such as the experience of hearing voices persistent despite treatment.
- Trial name
- DecNef (NCT07779226)
- Testing
- Decoded Neurofeedback
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Columbia University
Globus Pharyngeus
Bump the Lump - Intervention for the Treatment of Globus Pharyngeus
To develop a standardized speech-language pathology treatment protocol to systematically address Globus pharyngeus (GP) as a proof of concept
- Trial name
- NCT06762444
- Testing
- Speech-language pathologist (SLP) protocol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences