Clinical trials: Voice Change, open to volunteers
Functional Dysphonia, Resonance Tube Voice Therapy
Management of Non-Organic Dysphonia in Adults.
The purpose of this study is to determine the effect of a semi-occluded vocal tract training program, "Resonant Tube Therapy," versus the "Traditional Smith-accent Method" on the quality of voice in patients with Non-Organic…
- Conditions
- Functional Dysphonia, Resonance Tube Voice Therapy, Smith Accent Method Therapy
- Trial name
- NCT06856785
- Testing
- Resonance Tube Voice Therapy in Water
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pelvic Floor Dyssynergia, Phonation Disorder
Dynamics of Pelvic Floor Muscles With Different Phonation Patterns Among Female Students
The purpose of the study is to know if there is relation between the dynamics of pelvic floor muscles and different phonation pattern.
- Trial name
- NCT06716268
- Testing
- phonation and respiratory tasks
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cough, Vocal Cord Atrophy
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who are undergoing superior laryngeal nerve block, injection laryngoplasty…
- Conditions
- Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis
- Trial name
- NCT06579989
- Testing
- Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Laryngeal Dystonia, Focal Dystonia
Effects of Neuromodulation in Laryngeal Dystonia
Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life.
- Trial name
- NCT05095740
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Spasmodic Dysphonia, Singer's Dystonia
Brain Networks in Dystonia
To date, there is only limited knowledge about the distinct neural abnormalities that lead to the development of different forms of focal dystonia.
- Conditions
- Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia
- Trial name
- NCT03042962
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Laryngeal Dystonia, Spasmodic Dysphonia
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain…
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05216770
- Testing
- Brain imaging, Laryngeal sensory block with topical bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Oncologic Diseases, Cancer
Implementation and Evaluation of a Program Aimed at Facilitating Palliative Care Conversations
Cancer is one of the leading causes of death worldwide. In the care of people with cancer, it is essential to pay sufficient attention to individual care needs and quality of life.
- Trial name
- MCMV (NCT07402057)
- Testing
- My Care My Voice Intervention
- Where
- 4 sites in Belgium
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Functional Voice Disorder, Psychogenic Voice Disorder
Autonomic Dysfunction in Functional Dysphonia
The first objective of this research project is to compare the occurrence and frequency of symptoms and/or disorders related to autonomic dysfunction in patients with functional dysphonia with gender- and age-matched vocally…
- Conditions
- Functional Voice Disorder, Psychogenic Voice Disorder, Muscle Tension Dysphonia
- Trial name
- NCT06100601
- Testing
- ANS regulation therapy, conventional voice therapy (CVT), ANS regulation therapy + CVT
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Transitioning Voice of Transgender and Gender Diverse People
Novel Delivery Method of Transgender Voice Modification Training Using a Mobile Application
The investigators hypothesize that the mobile application they developed for transgender and gender diverse individuals (TGGD) will be equivalent or better than traditional speech therapy in improving voice quality.
- Trial name
- NCT05815810
- Testing
- Attuned: A mobile application, In-Person Voice Modification Therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Laryngeal Dystonia, Spasmodic Dysphonia
Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor
The researchers will systematically evaluate current and novel clinical voice assessment tools and measures to elucidate distinct clinical phenotypes of those with laryngeal dystonia and voice tremor.
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05150106
- Testing
- Clinical assessments of laryngeal function
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Laryngeal Dystonia
Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia
Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production.
- Trial name
- Neuro-VTS-LD (NCT07443891)
- Testing
- Vibrotactile Stimulation (VTS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Laryngeal Dystonia
Brain-Computer Interfaces in Laryngeal Dystonia
The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.
- Trial name
- NCT04421365
- Testing
- neurofeedback brain-computer interface (BCI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kristina Simonyan
Myasthenia Gravis, Fatigue
Capturing Key MG-symptoms Using Smartphone Recordings.
This study will make use of a cross-sectional design of MG patients and non-MG participants to quantitatively assess key MG symptoms, and to explore the applicability of machine learning algorithms to their measurement.
- Trial name
- CAPTURE - MG (NCT06743490)
- Where
- 2 sites in Netherlands
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Mitigation of Acute Voice Changes Follwing Rigorous Voice Use
Effect of Fish Oil Supplementation on the Voice of Female Professional Voice Users (PVU)
The design of the study allows us to test if there are differences in a battery of voice assessments (Aim 1) and biomarkers from vocal fold secretions (Aim 2) over time (within-subjects factor with 6 levels: 3 pre-intervention…
- Trial name
- PVU (NCT07800702)
- Testing
- Omega-3 Polyunsaturated Fatty Acids
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor University
Dysphonia, Aphonia
A Personalized Voice Restoration Device for Patients With Laryngectomy
The investigators will conduct a pilot experiment for a novel and personalized method for voice restoration using machine learning applied to surface EMG (sEMG) signal from articulatory muscles of the face and the neck allowing…
- Trial name
- NCT05479643
- Testing
- Surface Electromyography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Dysphonia, Muscle Tension Dysphonia
Translaryngeal Vibration for Hyperfunctional Voice Disorders
Contemporary treatments for hyperfunctional voice disorders such as muscle tension dysphonia (MTD) are effective but typically do not restore voice handicap or voice function to normal thresholds.
- Trial name
- NCT07145086
- Testing
- Voice therapy with vibration
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas Christian University