Clinical trials: Voice Hoarseness
Spasmodic Dysphonia
A Phase 2 Trial of Deep Brain Stimulation for Spasmodic Dysphonia
Spasmodic Dysphonia (SD) is a focal, action-specific movement disorder with prominent effects on speech (1, 2). Patients with SD lose their ability to speak normally due to involuntary contractions of their laryngeal muscles.
- Trial name
- NCT04938154
- Testing
- DBS ON, DBS OFF
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of British Columbia
Laryngeal Injury, Hoarseness
Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
The goal of this randomized clinical trial is to compare two different orotracheal tubes in patients which require orotracheal intubation for general anesthesia.
- Conditions
- Laryngeal Injury, Hoarseness, Cough, Sore-throat
- Trial name
- Triglotix® (NCT06108271)
- Testing
- Triglotix®, Conventional endotracheal tube
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Voice Disorders, Vocal Fold Polyp
Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction
Vocal hyperfunction (VH) is the most commonly treated class of voice disorders by speech-language pathologists and voice therapy is the primary curative treatment.
- Conditions
- Voice Disorders, Vocal Fold Polyp, Vocal Nodules in Adults, Muscle Tension Dysphonia
- Trial name
- NCT05970562
- Testing
- Ambulatory Voice Monitoring with Biofeedback (AVM-B), Conversation Training Therapy
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Presbylarynx, Atrophy; Larynx
Serial Platelet-Rich Plasma Injections for Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis
This study will investigate the safety and efficacy of four serial monthly vocal fold injections of platelet-rich plasma to treat dysphonia secondary to vocal fold atrophy, scar, and/or sulcus vocalis with glottal insufficiency
- Conditions
- Presbylarynx, Atrophy; Larynx, Dysphonia, Vocal Cord Atrophy
- Trial name
- NCT03749863
- Testing
- Serial PRP injections
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Secondary Hyperparathyroidism Due to Renal Causes
Pulmonary Function, Voice and Swallowing Symptoms After Parathyroidectomy
In this study, investigators measure patient's voice frequency, swallowing function, and O2 desaturation of the 6 mins walking test before surgery and 4 months after surgery, to find the increase of voice frequency, and…
- Trial name
- NCT04267965
- Testing
- parathyroidectomy plus bilateral thymectomy and autotransplantation
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Complications, Postoperative Pain
Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal Mask
The purpose of this study is to evaluate gender specific risk factors and the influence of cuff pressure in the occurrence of postoperative sore throat and hoarseness following general anaesthesia using Ambu® AuraGain™ Laryngeal…
- Trial name
- LadyLAMA (NCT04915534)
- Testing
- Ambu® AuraGain™ Laryngeal Mask (LM)
- Where
- Germany
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Endotracheal Tube, Cuff Pressure
The Effect of Monitoring Endotracheal Tube Cuff Pressure and Keeping it in a Certain Range
The main purpose of our prospective, randomized, controlled, double-blind study is to investigate the effect of keeping endotracheal tube cuff pressures within a certain range on the incidence of postoperative sore throat…
- Conditions
- Endotracheal Tube, Cuff Pressure, Sore Throat
- Trial name
- NCT06353932
- Testing
- keeping the endotracheal tube cuff pressure within a certain range
- Where
- Turkey (Türkiye)
- Volunteers
- 263 people
- Sponsor
- Hacettepe University
Dysphonia
Intensive Versus Traditional Voice Therapy
The purpose of this study is to determine if there are differences in treatment outcomes between traditional voice therapy, performed weekly for a maximum of 6 weeks versus intensive voice therapy, consisting of 4-6 therapy…
- Trial name
- NCT03129880
- Testing
- Weekly Voice Therapy, Intensive Voice Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Voice Change, Suboccipital Muscles Tension
Correlation Between Voice Pitch Changes and Tension of Suboccipital Muscles In Normal Subjects
this study for investigation of correlation between voice pitch and tension of suboccipital muscles
- Trial name
- NCT07008859
- Where
- Egypt
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Cairo University
Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness
Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy
Abstract Objective: The aim of this study is to compare two different ways of adjusting the air-filled cushion (cuff) of the breathing tube used during general anesthesia in children undergoing laparoscopic appendectomy (closed…
- Conditions
- Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness, Airway Complications, Respiratory Complications
- Trial name
- NCT07678086
- Testing
- Pressure Transducer, Traditional Palpation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Vocal Fold Paresis, Laryngeal Dystonia
Monitoring of the Safety and the Performance of the Endoscopic Cap Electrode (ECE50)
The objective of this registry is to confirm the safety and the performance of the ECE50 in medical routine by collecting data.
- Trial name
- ECE50 (NCT05245942)
- Where
- Austria
- Volunteers
- 384 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Dysphonia, Fibromyalgia
Relationship Between Dysphonia And Anxiety In Fibromyalgia
Our aim in conducting this study is to determine the relationship between voice disorders and anxiety in patients with fibromyalgia syndrome (FS).
- Conditions
- Dysphonia, Fibromyalgia, Anxiety Disorders
- Trial name
- NCT05410756
- Testing
- Assessment of Voice Quality and Function
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Spasmodic Dysphonia, Singer's Dystonia
Brain Networks in Dystonia
To date, there is only limited knowledge about the distinct neural abnormalities that lead to the development of different forms of focal dystonia.
- Conditions
- Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia
- Trial name
- NCT03042962
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Presbylarynx, Aspiration
Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
A previous study completed in 2022 (NCT05158179) was conducted using cohorts of healthy controls, and adults with general laryngopharyngeal disorders.
- Conditions
- Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus
- Trial name
- NCT06078527
- Testing
- Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Pharyngitis, Dysphonia
The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat
Post-operative sore throat (POST) ranks as the 8th most undesirable effect in the post-operative period and is noted by up to 90% of patients receiving an endotracheal tube.
- Trial name
- NCT03720301
- Testing
- Osteopathic Manipulation Treatment
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Intubation, Intratracheal, Postoperative Complications
Endobronchial Intubation of Double-lumen Tube: Conventional Method vs Fiberoptic Bronchoscope Guide Method
Double lumen tube (DLT) needs to be intubated to isolate ventilations of left and right lungs for thoracic surgery. Post-operative sore throat and hoarseness are more frequent with DLT intubation than with single one.
- Conditions
- Intubation, Intratracheal, Postoperative Complications, Sore Throat, Hoarseness
- Trial name
- NCT03368599
- Testing
- Bronchoscope guided advancement, Conventional advancement
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Bundang Hospital
Alzheimer Disease, Caregiver Burden
Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease
This research study is investigating whether people with Alzheimer's disease experience more changes to voice and swallowing than their healthy age-matched peers.
- Conditions
- Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphonia
- Trial name
- NCT06328374
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Laryngeal Dystonia
Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia
Laryngeal dystonia (LD) is a focal dystonia affecting laryngeal muscles, causing involuntary spasms that impair speech production.
- Trial name
- Neuro-VTS-LD (NCT07443891)
- Testing
- Vibrotactile Stimulation (VTS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dysphonia
Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Despite the considerable use of oral steroids in the regular management of benign vocal fold lesions there is little evidence base in the literature.
- Trial name
- AAO (NCT02286960)
- Testing
- Steroid, Lactose Pills
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Functional Voice Disorder
Improvement in Acoustic Voice Characteristics in Functional Dysphonia After Therapy
In a retrospective analysis of already existing clinical assessment data from patients with functional voice disorders the following aspects will be sampled, encoded and analysed: Outcomes pre and post treatment of 1.
- Trial name
- NCT02518425
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich