Clinical trials: Voiding Disorders, open to volunteers
Bone Resorption
Bone Substitutes Outcomes - Post Market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Bone Substitute range of products: CERAFORM, TRIHA+, NANOGEL, and all their private labels.
- Trial name
- NCT06374342
- Testing
- Bone defect, Spine fusion, Cage filling
- Where
- 6 sites in France, Germany
- Volunteers
- 425 people
- Sponsor
- Teknimed
Urinary Incontinence
Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult
The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population.
- Trial name
- OUTPACE (NCT06040645)
- Testing
- APP Co-management, E-consult
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Patch Electrode
UCon is a medical device for treating the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behavior of the bladder/bowel musculature e.g.…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT06754189
- Testing
- Time Limited stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- InnoCon Medical
Uterine Cervical Neoplasm, Uterine Cervical Dysplasia
Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples
The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers.
- Conditions
- Uterine Cervical Neoplasm, Uterine Cervical Dysplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- COMBISCREEN (NCT06598176)
- Testing
- Colli-Pee 20mL device with UCM, Evalyn Brush
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universiteit Antwerpen
Primary Nocturnal Enuresis, Nocturnal Enuresis in Children
Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis
The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin…
- Trial name
- NCT06883851
- Testing
- Structured pelvic floor rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bahçeşehir University
Diabetic Kidney Disease, Diabetic Nephropathies
Systemic Immune-Inflammation Index and Platelet Parameters in Diabetic Kidney Disease
Diabetic kidney disease (DKD) is a frequent microvascular complication in individuals with type 2 diabetes mellitus (T2DM) and a major cause of chronic kidney failure worldwide.
- Conditions
- Diabetic Kidney Disease, Diabetic Nephropathies, Type 2 Diabetes Mellitus, Albuminuria
- Trial name
- NCT07773467
- Volunteers
- 120 people
- Sponsor
- Assiut University
Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS)
Reducing Disparities in Urinary Control Symptoms for Minority Women
The study is designed to address the disparity in available conservative/behavioral treatments for UI/LUTS. The program was developed by experts from urogynecology, psychology, and physical therapy then modified based on focus…
- Conditions
- Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS), Pelvic Floor Disorder
- Trial name
- SUPPORT (NCT06798311)
- Testing
- SUPPORT workbook
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Overactive Bladder (OAB), Urge Incontinence
Assessing the Genitourinary Microbiome of Women With Overactive Bladder Undergoing Onabotulinum Toxin Type A Intradetrusor Injections
Single-site prospective observational pilot feasibility study of women with overactive bladder/urge urinary incontinence undergoing onabotulinum toxin type A intradetrusor injections in order to achieve the following objectives…
- Trial name
- MICROAB_Pilot (NCT07025044)
- Testing
- onabotulinum toxin type a
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alexis Dieter
Participants With Underactive Bladder (UAB)
A Proof-Of-Concept (POC) Study of SFG-02 Transdermal Formulation in Participants With Underactive Bladder (UAB)
The objective of this POC (Phase 2a) study is to evaluate the effect on Bladder Voiding Efficiency (BVE) as well as safety of SFG-02 transdermal formulation in participants with UAB.
- Trial name
- NCT07906106
- Testing
- SFG-02
- Where
- 16 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Juro Sciences Inc.
Stress Urinary Incontinence (SUI), Sexual Dysfunction
Effect of Knack Pelvic Floor Contraction on Sexual Dysfunction
This study aims to investigate the effect of knack pelvic floor contraction on sexual dysfunction in females with stress urinary incontinence.
- Trial name
- NCT07145216
- Testing
- Interfrential stimulation, Knack pelvic floor training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pelvic Floor Dysfunction, Urinary Incontinence
Impact of Equestrian Sports, CrossFit, and Gym Training on Pelvic Floor Health (PELFISPORT )
This observational cross-sectional study investigates the impact of equestrian sports, CrossFit, and gym training on pelvic floor health in both athletes and non-athletes.
- Conditions
- Pelvic Floor Dysfunction, Urinary Incontinence, Pelvic Organ Prolapse (POP), Chronic Pelvic Pain
- Trial name
- PELFISPORT (NCT06848634)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Hematuria
Study on Risk Assessment for Patients With Microscopic Hematuria (Non-Visible Blood in Urine) Using a Urine Marker Test
The goal of this clinical study is to learn how well a urine test called Xpert® Bladder Cancer Detect (Xpert BC-D) can help doctors assess the risk of bladder cancer in people with non-visible blood in their urine (microscopic…
- Trial name
- UroDetect III (NCT07307300)
- Where
- Germany
- Volunteers
- 1,475 people
- Sponsor
- Christian Bolenz
Stress Urinary Incontinence
Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System
The objective of this single arm, post market, clinical study is to evaluate the performance of Gynecare TVT ABBREVO® Continence System in women undergoing Mid-urethral sling surgery for Stress Urinary Incontinence (SUI).
- Trial name
- NCT04829357
- Testing
- Intervention
- Where
- 4 sites in United States, Italy and 1 more
- Volunteers
- 195 people
- Sponsor
- Ethicon, Inc.
Stress Urinary Incontinence (SUI)
The Effect of Different Delivery Positions on Pelvic Floor Function.
This study is a prospective, multicenter, randomized controlled trial. Baseline data will be collected from eligible subjects recruited during the third trimester of pregnancy.
- Trial name
- NCT07081321
- Testing
- Lithotomy position, Lateral Position, Upright Position
- Where
- China
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Evaluation of the new Axonics External Trial System (ETS-02) in patients with overactive bladder (OAB) and/or fecal incontinence (FI).
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
- Trial name
- NCT07335484
- Testing
- Axonics External Trial System (ETS)
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- Axonics, Inc.
Stress Urinary Incontinence
Impact of Virtual Reality Pelvic Floor Training on Postpartum Stress Urinary Incontinence
This study will be conducted to determine the effect of virtual reality (VR) on pelvic floor training on postpartum stress urinary incontinence (SUI) .
- Trial name
- NCT07455838
- Testing
- Pelvic floor muscle rehabilitation supported by an immersive VR, Medical treatment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Obesity; Chronic Kidney Disease; Albuminuria
Study on the Efficacy and Safety of Initial Combination of Finerenone and Semaglutide in Non-Diabetic Adult Patients With Obesity Complicated by Chronic Kidney Disease With Albuminuria
This multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate whether starting finerenone together with semaglutide provides an additional reduction in urinary albumin-to-creatinine ratio…
- Trial name
- NCT07849348
- Testing
- Finerenone, Semaglutide
- Volunteers
- 266 people
- Sponsor
- Peking University People's Hospital
Chronic Kidney Disease, Type 2 Diabetes
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
The goal of this clinical trial is to learn if starting four kidney disease medicines quickly and together (a rapid treatment approach) is safe and works well in people with type 2 diabetes and chronic kidney disease.
- Trial name
- RAPID-CKD (NCT07547878)
- Testing
- Finerenone, Semaglutide, Lotensin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Baylor Research Institute
Dysfunctional Voiding, Stress Incontinence, Urinary
Case Control Study to Investigate the Use of Urethral Pressure Profile Measurement in Children
The bladder has a muscle that acts like a tap called the sphincter. Just like a tap, when pee is stored the sphincter muscle is closed and during peeing the sphincter opens.
- Trial name
- NCT04147793
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London