Clinical trials: Voiding Disorders
Overactive Bladder
A Study of YM178 in Patients With Symptomatic Overactive Bladder (DRAGON)
The study will examine which dose of YM178 is best in terms of efficacy, safety and tolerability compared to placebo and compared to tolterodine, a marketed product.
- Trial name
- NCT00337090
- Testing
- YM178
- Where
- 84 sites in Belgium, Czechia and 13 more
- Volunteers
- 1,108 people
- Sponsor
- Astellas Pharma Inc
Rectal Neoplasms
Exercise Training for Rectal Cancer Patients
Cancer treatments often cause acute toxicity during treatment, and late toxicity after treatments have ended. Bowel dysfunctions, incontinence (anal and urinary) and dysfunction are late side effects associated with cancer…
- Trial name
- NCT02538913
- Testing
- Exercise training, Usual care
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Stress Urinary Incontinence
Virtue® European Study
This study is a prospective, single arm, non-randomized, multi-center clinical study that will be conducted in Europe. It is designed to assess efficacy and safety of the Virtue® Male Sling in post-prostatectomy urinary…
- Trial name
- NCT01608789
- Testing
- Virtue® Male Sling
- Where
- 14 sites in Belgium, France and 6 more
- Volunteers
- 123 people
- Sponsor
- Coloplast A/S
Urinary Incontinence, Stress Urinary Incontinence
Lessening Incontinence by Learning Yoga
The purpose of this study is to assess the feasibility of recruiting women with urinary incontinence into a randomized controlled trial of a yoga therapy program.
- Conditions
- Urinary Incontinence, Stress Urinary Incontinence, Urge Urinary Incontinence, Over Active Bladder
- Trial name
- LILY (NCT01672190)
- Testing
- Yoga Therapy Program
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Urinary Incontinence (UI), Prostatectomy
Transcutaneous Tibial Nerve Stimulation for Urinary Incontinence After Radical Prostatectomy
Urinary incontinence (UI) after radical prostatectomy (RP) is a common postoperative complication that significantly affects quality of life.
- Trial name
- NCT07742176
- Testing
- Active Transcutaneous Tibial Nerve Stimulation (TTNS), Pelvic Floor Muscle Training (PFMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Pamukkale University
Stress Urinary Incontinence
Lyrette: Renewing Continence Objective and Subjective Efficacy Study
The purpose of this study is to demonstrate the treatment efficacy of the Lyrette® System in women most likely to be treated in an office setting for the condition of stress urinary incontinence, secondary to urethral…
- Trial name
- ROSE (NCT01455779)
- Testing
- Lyrette
- Where
- 6 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Verathon
Vaginal Atrophy
A Clinical Clinical Observation of CO2 Fractional Laser in Female Vaginal Repair
1. Vaginal atrophy is the most common indication in the treatment of vaginal rejuvenation. Its main manifestation is vaginal relaxation syndrome, which may be the early symptom of female pelvic floor dysfunction.
- Trial name
- NCT04492176
- Testing
- CO2 fractional laser（ACUPULSE,Lumenis）
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Urinary Stress Incontinence
Hypertonic Saline Injection For Urinary Incontinence
The investigators aimed to evaluate the effectiveness and safety of periurethral hypertonic saline (10% NaCl) injection for the treatment of stress urinary incontinence (SUI) and stress-predominant mixed urinary incontinence…
- Trial name
- NCT04812574
- Testing
- Periurethral injection, Hypertonic (10%) saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Turgut Ozal University
Incontinence, Urinary, Enuresis, Nocturnal
Alarm Treatment for Combined Enuresis and Daytime Urinary Incontinence in Children
The aim is to examine whether alarm therapy in addition to urotherapy can have a beneficial effect in treating urinary incontinence children with combined daytime incontinence and enuresis.
- Conditions
- Incontinence, Urinary, Enuresis, Nocturnal, Enuresis
- Trial name
- ABDE (NCT04260646)
- Testing
- Enuresis Alarm Rodger and Timer watch (Rodger), Timer watch (Rodger)
- Where
- 4 sites in Denmark
- Volunteers
- 89 people
- Sponsor
- Aalborg University Hospital
Proteinuria, Transplant Glomerulopathy
Acthar as Rescue Therapy for Transplant Glomerulopathy in Kidney Transplant Recipients
The goal of this study is to evaluate the benefit of ACTH (Acthar) in reducing proteinuria associated with transplant glomerulopathy in non-diabetic kidney transplant recipients.
- Trial name
- NCT02057523
- Testing
- Acthar
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Illinois at Chicago
Stress Urinary Incontinence
Vesair Balloon Confirmatory Trial (VECTOR)
Multicenter, prospective, single-arm study to assess the safety and efficacy of the Vesair Bladder Control treatment in post-menopausal women with Stress Urinary Incontinence (SUI) with follow-up at 1, 3 and 12 months.
- Trial name
- VECTOR (NCT03794206)
- Testing
- Vesair Balloon
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- Solace Therapeutics, Inc.
Electrical Stimulation
Electrical Stimulation in Men With Urinary Incontinence After Radical Prostatectomy
Aim: In this study, the investigators aimed to assess the efficacy of perineal electrical stimulation on anxiety, depression, quality of life (QOL), and clinical parameters associated with incontinence in men with urinary…
- Trial name
- NCT05236140
- Testing
- Perineal electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Urinary Incontinence
Muscle Progenitor Cell Therapy for Urinary Incontinence
This study is designed to evaluate the safety of muscle progenitor cells (MPCs) for the treatment of urinary incontinence due to incompetent outlet (bladder neck/urethra).
- Trial name
- MPC (NCT01953315)
- Testing
- Autologous Muscle Progenitor Cells
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University
Overactive Bladder, Urinary Incontinence, Urge
Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPO
comparing the outcome of low-intensity shock wave therapy (Li-SWT) versus solifenacin on persistent storage symptoms after transurethral surgery for benign prostatic obstruction (BPO)
- Conditions
- Overactive Bladder, Urinary Incontinence, Urge, Urgency-frequency Syndrome, Post Prostatectomy
- Trial name
- NCT04437108
- Testing
- Li-SWT (suprapubic approach), Li-SWT (perineal approach), Li-SWT (combined approach)
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Mansoura University
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pelvic Organ Prolapse, Urinary Incontinence
Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Diagnosis
- Trial name
- NCT06372340
- Testing
- Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system., Standard pelvic floor muscle training(PFMT) program
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Overactive Bladder, Urge Incontinence
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults
For overactive bladder symptoms, there are numerous physiotherapy techniques have been found to be beneficial. Transcutaneous electrical stimulation of the tibial nerve is one of those treatment options, that is entirely a…
- Conditions
- Overactive Bladder, Urge Incontinence, Nocturia
- Trial name
- NCT05464589
- Testing
- Transcutaneous tibial nerve stimulation along with pelvic floor muscle srengthening, Pelvic floor muscles strengthening
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Urinary Incontinence
Comparison of Body and Room Temperature Saline in Urodynamics
The purpose of this study is to compare first urge, strong urge, and maximum capacity, and perception of discomfort during urodynamic testing between room temperature and body temperate saline.
- Trial name
- NCT00355433
- Testing
- Urodymanics
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tripler Army Medical Center
Cystocele, Stress Urinary Incontinence
Anterior Defect Correction With Mesh Plus Treatment of Stress Incontinence With Transobturator or Transvaginal Approach
The incidence of anterior pelvic defect in women is estimated about 10% and it may be often associated to urinary stress incontinence.
- Trial name
- NCT00743535
- Testing
- Transobturatory correction of anterior defect plus TOT, Transobturatory correction of anterior defect plus TVT
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia
Urinary Incontinence
Effectiveness of PeeRelease - a Gel Absorbent Pad in Moderate to Severe Urinary Incontinence
The purpose of the proposed study is to test the effect of the new gel pad on the quality of life of urinary incontinent men and women and to assess to what extent the gel pad improves the quality of life of incontinence persons.
- Trial name
- NCT01066117
- Testing
- PeeRelease gel absorbent pad
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tisteron Ltd.