Clinical trials: Voiding Disorders
Incontinence, Urinary and Urinary Bladder, Overactive, Overactive Bladder
Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients
This is a two-part study in which Part A will assess the effects of GW679769 after 1 dose on the function of the nerves that supply the bladder. The technique for measuring the nerves function is called Neurometry.
- Trial name
- NCT00332319
- Testing
- GW679769
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Overactive Bladder, Parkinson Disease
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease
The impact of urinary symptoms in Parkinson disease (PD) extends beyond worsened well-being. Urinary symptoms common in PD, especially incontinence and nocturia, are major risk factors for falls likely due to the combination of…
- Trial name
- BOSS PD (NCT03149809)
- Testing
- solifenacin, Pelvic floor muscle exercise-based behavioral therapy
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Incontinence, Urinary
Clinical Study Investigating Safety and Performance of a New Urinary Intermittent Catheters in Healthy Volunteers
The aim of the study is to test the performance and safety of a newly developed intermittent catheter
- Trial name
- NCT02965105
- Testing
- Coloplast Test Catheter, Speedicath
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Overactive Bladder, Overactive Bladder Syndrome
Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children
The purpose of this study is to find out if overactive bladder (OAB) can be safely treated by stimulating a nerve near the ankle. This procedure is called percutaneous tibial nerve stimulation (PTNS).
- Trial name
- POSITRON-C (NCT06769854)
- Testing
- Urgent PC
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chi Dang Hornik
Neurogenic Bladder, Urinary Retention
Qualitative Assessment of the Impact of TTNS on QOL and Participation
This study through the use of semi-structured interviews or focus groups will explore the lived experience with Transcutaneous Tibial Nerve Stimulation (TTNS) with Neurogenic Lower Urinary Tract Dysfunction to generate…
- Conditions
- Neurogenic Bladder, Urinary Retention, Urinary Tract Infections, Spinal Cord Injuries
- Trial name
- NCT04248322
- Testing
- Semi-structured interview
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Medstar Health Research Institute
Urinary Incontinence
Conveen Optima Urisheaths With Collecting Bags Versus Absorbents
The objective of this investigation is to asses with validated scales, the impact on the quality of life of men suffering of moderate to severe incontinence of the use of Conveen Optima urisheath in comparison with their usual…
- Trial name
- NCT01056666
- Testing
- Conveen Optima is a urisheath to be used together with a collecting bag for urine, absorbent protection
- Volunteers
- 61 people
- Sponsor
- Coloplast A/S
Urinary Incontinence
Does Posterior Reconstruction of the Rhabdosphincter Improve Early Recovery of Continence After Robotic-Assisted Radical Prostatectomy?
The present study is a multicenter randomized, controlled trial, whose aim is to verify the effect of the posterior reconstruction of the rhabdosphincter after robot-assisted radical prostatectomy on early recovery of urinary…
- Trial name
- PRR (NCT01809522)
- Testing
- Posterior reconstruction of the rhabdosphincter
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Urinary Incontinence
Computerized-Adaptive Testing: Feasibility In Women With Pelvic Floor Disorders (CAT)
The objective of this pilot-study is to evaluate the feasibility and acceptability of PROMIS computerized-adaptive testing in women with urinary incontinence.
- Trial name
- CAT (NCT01288703)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Urge Incontinence
InterStim® Amplitude Study
This feasibility study will explore the effects of three different InterStim amplitude settings on overactive bladder symptoms (OAB).
- Trial name
- NCT03335761
- Testing
- InterStim Therapy
- Where
- 18 sites in United States, Belgium and 5 more
- Volunteers
- 97 people
- Sponsor
- MedtronicNeuro
Stress Urinary Incontinence
A Study to Evaluate the Effectiveness of the Induced Reflex Cough Test Plus Urodynamics to Identify Stress Urinary Incontinence in Female Subjects With a History of Stress Urinary Incontinence
This study is to evaluate the effectiveness of identifying stress urinary incontinence (SUI) in female subjects using the Induced Reflex Cough Test (IRCT) administered with urodynamic testing by evaluation of sensitivity and…
- Trial name
- NCT00801203
- Testing
- IRCT
- Where
- 10 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Pneumoflex Systems, LLC
Pelvic Organ Prolapse, Stress Urinary Incontinence
Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Surgery
Pelvic organ prolapse occurs with descent of one or more pelvic structures: the uterus and/or cervix, bowel, bladder, or rectum.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Satisfaction
- Trial name
- NCT02111642
- Testing
- Online risk calculator
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Hematuria, Retention, Urinary
Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia
Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to…
- Conditions
- Hematuria, Retention, Urinary, Operative Bleeding, Blood Transfusion Complication
- Trial name
- NCT05314582
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Bezmialem Vakif University
Proteinuria
Clinical Study on the Use of Huaier Granules for the Treatment of Proteinuria Related to Bevacizumab and Anlotinib in Lung Cancer Patients
This study is a prospective, multicenter, parallel-controlled clinical trial designed to evaluate the therapeutic efficacy of Huaier Granules for proteinuria occurring in lung cancer patients undergoing treatment with either…
- Trial name
- NCT07358520
- Testing
- Huaier Granule, Anlotinib and Bevacizumab
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Chronic Kidney Diseases, Cardiovascular Diseases
Dietary Acid Reduction and Progression of Chronic Kidney Disease
Upon completion, this project will determine if dietary acid reduction done with either fruits and vegetables (F+V) or the medication sodium bicarbonate (NaHCO3) in study participants with high blood pressure (hypertension) and…
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- NCT06046924
- Testing
- Fruits and vegetables (F+V), NaHCO3 Tablets, Usual Care
- Volunteers
- 153 people
- Sponsor
- Donald Wesson
Urinary Incontinence
Effects of Pelvic Floor Rehab Protocol on Urinary Incontinence
Urinary incontinence is a serious health issue that deeply affects a person's daily life and overall well-being. The global prevalence of UI is between 5 to 69% during a woman's lifetime, with higher prevalence in older age…
- Trial name
- NCT07603388
- Testing
- Pregnancy Specific Pelvic floor rehab protocol (PSPFR) Group, Standard Protocol for Pelvic floor strengthening
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Urinary Incontinence
Effects of Osteopathic Manipulations and Muscle Training on the Myoelectric Activity of the Pelvic Floor
The objective of this study was to compare the effects of four different interventions on pelvic floor muscle electromyographic activity in women with stress urinary incontinece: i) a global osteopathic protocol (myofascial…
- Trial name
- NCT04584359
- Testing
- HVLA, global osteopathic protocol, pelvic floor muscle training
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Giselle Notini Arcanjo
Quality of Life, Urinary Incontinence
The Pelvic Floor Function and Sexual Life of the Women After Different Type of Hysterectomy
In this prospective, comparative non-randomized multiple teaching hospitals study, the investigators try to determine the relationship of total hysterectomy and Taiwanese female pelvic floor and sexual function from the view of…
- Conditions
- Quality of Life, Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- HYS-PF-QOL (NCT02841059)
- Testing
- LSH, CLSH, LAVH
- Where
- 4 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Urinary Incontinence, Urinary Bladder, Overactive
Evaluation of Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korea
This study is a Post-Marketing Surveillance study in Korea to evaluate the safety and efficacy of botulinum toxin Type A to treat urinary incontinence in patients with neurogenic detrusor overactivity (NDO) or overactive bladder…
- Trial name
- NCT02010788
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 523 people
- Sponsor
- Allergan
Urinary Incontinence,Stress
Physiotherapy in Stress Urinary Incontinence
The goal of this randomized controlled trial is to evaluate and compare the effects of functional magnetic stimulation and pelvic floor muscle training on pelvic floor muscle function, urinary incontinence symptoms and quality of…
- Trial name
- NCT05721807
- Testing
- functional magnetic stimulation, pelvic floor muscle training program
- Where
- Lithuania
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC