Clinical trials: Voiding Dysfunction
Urinary Incontinence, Anal Incontinence
Tridimensional Pelvic Floor Ultrasound and Quality of Life Scores Questionnaires in Nulliparous or Parous Women
Evaluation of the impact of the delivery in the system of suspension and sustentation of pelvic floor, by 3D ultrasound and quality of life questionnaires.nt
- Conditions
- Urinary Incontinence, Anal Incontinence, Sexual Dysfunction, Self Esteem
- Trial name
- NCT03656601
- Testing
- 3D pelvic ultrasound
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Prostate Cancer, Sexual Dysfunction
High-Intensity Focused Ultrasound Ablation in Treating Patients With Localized Prostate Cancer
RATIONALE: Highly focused ultrasound energy may be able to kill tumor cells by heating the tumor without affecting the surrounding tissue.
- Conditions
- Prostate Cancer, Sexual Dysfunction, Urinary Incontinence
- Trial name
- NCT00561314
- Testing
- questionnaire administration, biopsy, high-intensity focused ultrasound ablation
- Where
- 2 sites in United Kingdom
- Volunteers
- 33 people
- Sponsor
- University College London Hospitals
BPH, Lower Urinary Tract Symptoms
HoLEP Sexual Survivorship
The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP).
- Trial name
- NCT07660068
- Testing
- Telephone Interview, Questionnaires over the span of 24 months
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Northwestern University
Sacral Neuromodulation
Preliminary Outcomes of Sacral Neuromodulation Applications; Tertiary-Center Experience in Turkey
to report our patients' outcomes of SNM in tertiary health centres in Turkey
- Trial name
- NCT06098963
- Testing
- sacral neuromodulation
- Volunteers
- 16 people
- Sponsor
- Cigli Regional Training Hospital
Urinary Retention
Treatment for Acute Postoperative Voiding Dysfunction
If patients are unable to have their foley catheter removed because their bladder is not emptying well, they may be eligible for study participation.
- Trial name
- PTNS (NCT01189136)
- Testing
- PTNS Active Treatment
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Urology, Pediatric Disorder
Pelvic Floor Muscle Training and Dynamic Neuromuscular Stabilization Exercises in Pediatric Patients
Dysfunctional voiding (DY) is one of the most common conditions in children. Various treatments are available. Participants will be randomly assigned to either PFMT (Group I) or PFMT+DNS (Group II).
- Trial name
- NCT07267364
- Testing
- PFMT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Vaginal Laxity, Urinary Incontinence
Evaluation Using Intragen Fractional Radiofrequency With NeuViVa for the Treatment of Vaginal Laxity and Urogynecology Symptoms.
This study will evaluate the clinical efficacy of a Transcutaneous Fractional Radiofrequency Device (TFRF) for the treatment of vaginal laxity (VL) and urogynecological symptoms.
- Conditions
- Vaginal Laxity, Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT03280446
- Testing
- Intragen fractional radiofrequency with NeuViVa
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SHERRY Thomas
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.
The goal of this clinical trial is to improve the management of Genitourinary syndrome of menopause (GSM) to preliminary assess safety and effectivity of a novel hormone-free mucosa composition (XCMIM20m) applied topically to the…
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Quality of Life
- Trial name
- STOPGSMP (NCT06962345)
- Testing
- Hormone-free vulvovaginal gel with the tested composition XCMIM20m
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Mucosa Innovations, S.L.
Detrusor Underactivity, Bladder Outlet Obstruction
DU and BOO in Women With and Without Symptoms of VD
Women with symptoms of voiding dysfunction may be associated with detrusor underactivity or bladder outlet obstruction. However, the prevalence of detrusor underactivity and bladder outlet obstruction remained obscure.
- Trial name
- NCT04981080
- Testing
- Urodynamic study
- Where
- Taiwan
- Volunteers
- 1,886 people
- Sponsor
- National Taiwan University Hospital
Proteinuria, Diabetic Nephropathy
FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients
There is no data about the effects of Renin angiotensin system blockage (RAS) on FGF23 and ADMA levels in diabetic patients with proteinuria.
- Conditions
- Proteinuria, Diabetic Nephropathy, Chronic Kidney Disease
- Trial name
- NCT01703234
- Testing
- Ramipril
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Prostate Cancer
IONM During Radical Prostatectomy
At present, the preferred treatment for patients with prostate cancer is still radical prostatectomy. Postoperative patients often face some complications, the most common complications include urinary incontinence and erectile…
- Trial name
- NCT06950216
- Testing
- IONM
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Proteinuria, Kidney Dysfunction
Azilsartan in Patients With Diabetic Kidney Disease and Hypertension
Hypertension is the most common complication in patients with diabetes nephropathy. Strengthening blood pressure and blood sugar control is the basic treatment for patients with diabetes nephropathy.
- Conditions
- Proteinuria, Kidney Dysfunction, Blood Pressure, Diabetic Kidney Disease
- Trial name
- NCT05753696
- Testing
- Azilsartan, Losartan
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stress Urinary Incontinence
Reducing Early Urinary Disorders After Stress Incontinence Surgery: The Role of Vaginal Wall Tension.
The progress in surgical procedures for treating female stress urinary incontinence has led to the development of tension-free techniques such as the trans-obturator tape (TOT).
- Trial name
- NCT06292702
- Testing
- Traditional Burch colposuspension, Modified Burch colposuspension
- Where
- Syria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dysfunctional Voiding, Urinary Dysfunction
At-Home Diaphragmatic Interventions for Voiding Abnormalities (DIVA)
The goal of the DIVA trial is to test the effectiveness of at-home diaphragmatic breathing exercises with bladder hygiene education in female patients with symptoms of difficulty urinating (dysfunctional voiding).
- Trial name
- DIVA (NCT06165731)
- Testing
- Diaphragmatic Breathing Exercises, Bladder Hygiene Education
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Duke University
Depressive Symptoms, Urinary Incontinence
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women
The goal of this clinical trial is to evaluate if the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices is able to improve depressive symptoms and sexual function in women who are perimenopausal or…
- Conditions
- Depressive Symptoms, Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT07413705
- Testing
- EXOMIND (BTL-699-2) Active Treatment, EMSELLA (HPM-6000UF) ActiveTreatment
- Where
- 3 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- BTL Industries Ltd.
Neurogenic Bladder Disorder, Non-Neurogenic Bladder
Define Final Selection Choice Criteria for a Coloplast Catheter Ensuring Highest Patient Satisfaction Via Surveys (EVA).
Understanding the Coloplast Intermittent Catheter Selection Study: This study aims to understand how adults who need to use catheters to empty their bladder by themselves decide which Coloplast catheter works best for them.
- Conditions
- Neurogenic Bladder Disorder, Non-Neurogenic Bladder, Bladder Dysfunction, Urinary Retention
- Trial name
- EVA (NCT07355803)
- Testing
- Questionnaires : Patient questionnaire on catheter use and satisfaction, IC-Di-Q, and I-CAT
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Coloplast NV/SA
Sexuality, Sexual Dysfunction
Improving Female Sexual Wellness
The purpose of this study is to assess the effect of commercially available genital vibrator use on sexual health, female pelvic floor disorders, and overall quality of life among a diverse population of women.
- Conditions
- Sexuality, Sexual Dysfunction, Sexual Desire Disorder, Hypoactive Sexual Desire Disorder
- Trial name
- NCT04824820
- Testing
- Vibrator
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Cedars-Sinai Medical Center