Clinical trials: Volume
Volume Deficiency of the Midface
Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers
To assess and compare tissue aggregation and visualization of two Hyaluronic Acid fillers via ultrasound
- Trial name
- RES (NCT05622851)
- Testing
- Restylane Contour, Juvederm Voluma
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Moderate to Severe Midface Volume Deficit
Saypha® VOLUME Lidocaine for Midface Augmentation
The clinical investigation is a randomized, subject- and evaluator-blinded, active treatment controlled, multicenter, clinical investigation, to demonstrate the non inferiority of saypha® VOLUME Lidocaine to one of the devices…
- Trial name
- VOLIDO (NCT05386030)
- Testing
- saypha® VOLUME Lidocaine, Juvéderm® Voluma™ XC
- Where
- 16 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Facial Rhytides, Skin Folds
Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment
The primary objective of this study is to quantify the psychological, social, and emotional impact of comprehensive aesthetic treatment with a portfolio of the Sponsor's products by measuring the change in subject's satisfaction…
- Conditions
- Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
- Trial name
- NCT04609020
- Testing
- JUVÉDERM, BOTOX, HArmonyCA Lidocaine
- Where
- 6 sites in Brazil
- Volunteers
- 64 people
- Sponsor
- Allergan
Buttocks Volume Loss
Clinical Study for the Evaluation of the Effectiveness of Use of a Poly-L Lactic Acid Injectable Filler for the Aesthetic Treatment of Buttocks Volume Depression
The purpose of this study is to assess the effectiveness and safety of Gana X, a Poly L-lactic acid filler for the aesthetic treatment of buttocks.
- Trial name
- PLLA (NCT05363163)
- Testing
- Gana X
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GCS Co., Ltd
Midface Volume Deficit
Sculptra for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
This is a randomized, evaluator-blinded, no-treatment controlled study in participants with Midface Volume Deficit and/or Midface Contour Deficiency.
- Trial name
- NCT04132518
- Testing
- Sculptra
- Where
- 6 sites in China
- Volunteers
- 205 people
- Sponsor
- Galderma R&D
Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
To determine the efficacy, safety, and dose and regimen of tolvaptan in pediatric CHF patients with volume overload
- Trial name
- NCT03255226
- Testing
- Tolvaptan
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Volume Loss in the Infraorbital Hollow Area
Evaluation of Effectiveness and Safety of Belotero Balance® (+) Lidocaine for Volume Augmentation of the Infraorbital Hollow
Confirm the effectiveness of Belotero Balance® (+) Lidocaine (BBL) injection for the correction of volume loss in the infraorbital hollow (IOH) area by demonstrating superiority to untreated control.
- Trial name
- NCT04594239
- Testing
- Belotero Balance (+) Lidocaine, needle, Belotero Balance (+) Lidocaine, cannula, Untreated-control / delayed-treatment, needle
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 150 people
- Sponsor
- Merz North America, Inc.
Signs of Facial Aging With Volume Loss in the Upper Cheeks, Nasolabial Folds and Marionette Lines
Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
The primary objective is to collect clinical data to confirm performance and safety for RADIESSE® (+) Lidocaine, when used in accordance with its labelling in the treatment of nasolabial folds, marionette lines and/or upper cheek…
- Trial name
- RaLido (NCT03650387)
- Testing
- RADIESSE® (+) Lidocaine
- Where
- 7 sites in Germany
- Volunteers
- 207 people
- Sponsor
- Merz North America, Inc.
Volume Loss in the Dorsum of the Hand
Radiological Evaluation of Radiesse Implantation in the Hands
The objective of this study is to provide a preliminary assessment of the radiographic appearance of Radiesse material that has been injected into the dorsum of the hands.
- Trial name
- NCT02949921
- Testing
- Radiesse injectable implant and 2% lidocaine HCL
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Correction of Volume Loss in the Infraorbital Hollow Area
A Pilot Study to Assess the Effectiveness and Safety of Belotero Balance® Injection for Volume Augmentation of the Infraorbital Hollow
The pilot study aims to define safety, effectiveness, and patient-reported outcomes for Belotero Balance® use in the infraorbital hollows.
- Trial name
- NCT03777917
- Testing
- Belotero Balance®
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Merz North America, Inc.
Midface Volume Deficit
Restylane Perlane Lidocaine for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
This is a randomized, multi-center, evaluator-blinded, no-treatment controlled study to evaluate the efficacy and safety of Restylane Perlane Lidocaine for correction of Midface Volume Deficit and/or Midface Contour Deficiency.
- Trial name
- NCT03097783
- Testing
- Restylane Perlane Lidocaine
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Galderma R&D
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
The objective of this study is to quantify the psychological and emotional impact of comprehensive aesthetic treatment with a portfolio of Allergan products by measuring the change in participant's satisfaction with facial…
- Trial name
- NCT03712449
- Testing
- JUVÉDERM®, BOTOX Cosmetic®, BELKYRA®
- Where
- 7 sites in Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Midface Volume Deficit
Restylane Volyme for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
This is a randomized, evaluator-blinded, no-treatment controlled study in subjects with Midface Volume Deficit and/or Midface Contour Deficiency.
- Trial name
- NCT03289052
- Testing
- Restylane Volyme
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Galderma R&D
Volume Loss (Soft Tissue Ptosis or Atrophy )
Pan Facial Volume Restoration
The aim of this study is to assess performance and tolerance as well as investigator and subject satisfaction further to pan-facial volume restoration with a new cross-linked hyaluronic acid dermal filler containing lidocaine…
- Trial name
- EVE (NCT01545557)
- Testing
- Hyaluronic acid dermal filler gel
- Where
- 3 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Volume Restoration and Shaping of the Buttocks
A Study to Evaluate Efficacy and Safety of Macrolane VRF30 for Volume Restoration and Contouring of the Buttocks
The purpose of the study is to evaluate the efficacy and safety of Macrolane for volume restoration and shaping of the buttocks.
- Trial name
- NCT01331408
- Testing
- Macrolane VRF30
- Where
- 4 sites in Belgium, Spain and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Volume Deficit in the Hand
Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand
This is a randomized, evaluator-blind, split hand, multi-center study of the effectiveness and safety or Restylane Lyft with Lidocaine compared to no treatment for injection in the dorsal hand to correct volume deficits.
- Trial name
- NCT02650921
- Testing
- Restylane Lyft with Lidocaine
- Where
- 7 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Volume Deficiency of the Midface
A Study to Evaluate Effectiveness and Safety of Hyaluronic Acid (HA) Fillers
The purpose of the study is to investigate the degree of improvement in appearance after treatment with different hyaluronic acid (HA) fillers.
- Trial name
- 05DF1707 (NCT03869450)
- Testing
- Restylane Volyme, Restylane Defyne, Restylane Lyft Lidocaine
- Where
- 3 sites in Germany, Italy and 1 more
- Volunteers
- 90 people
- Sponsor
- Galderma R&D
Acute Heart Failure, Cardiac Decompensation
Global rEgistry on decongestioN Therapy Using Less invasivE UltraFiltration
In patients with advanced volume overload, minimally invasive ultrafiltration treatment in the acute phase can have a positive effect on clinical outcome.
- Conditions
- Acute Heart Failure, Cardiac Decompensation, Volume Overload
- Trial name
- GENTLE-UF (NCT02769351)
- Testing
- periph. minimal invasive ultrafiltration
- Where
- 19 sites in Germany, Sweden and 1 more
- Volunteers
- 104 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Volume Loss of the Jawline
Evaluation of the MJGS Following Radiesse (+) Injection Into the Jawline
This study will evaluate the sensitivity of the validated Merz Jawline Grading Scale (MJGS) to detect treatment effects following Radiesse (+) correction of subcutaneous volume loss and contour deficits of the jawline.
- Trial name
- NCT02904057
- Testing
- Radiesse (+) Injectable Implant
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Volume Loss in the Dorsum of the Hand
Radiesse® Safety Study For the Treatment of Hands
The primary objective of this study is to evaluate the safety of Radiesse implantation for very severe volume loss in the dorsum of the hand at 6 months after treatment.
- Trial name
- NCT02904096
- Testing
- Radiesse injectable implant and 2% lidocaine HCL
- Where
- 9 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.