Clinical trials: Volume Assessment
Injection Techniques
Study to Evaluate Efficacy, Safety and Injection Technique of Restylane Lip Volume and Restylane Lip Refresh
The purpose of this study is to demonstrate the efficacy and safety of two new Restylane Lip products, Restylane Lip Volume and Restylane Lip Refresh, and to collect information on the injection technique.
- Trial name
- NCT01428024
- Testing
- Restylane Lip Volume, Restylane Lip Refresh
- Where
- 3 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Moderate to Severe Midface Volume Deficit
Saypha® VOLUME Lidocaine for Midface Augmentation
The clinical investigation is a randomized, subject- and evaluator-blinded, active treatment controlled, multicenter, clinical investigation, to demonstrate the non inferiority of saypha® VOLUME Lidocaine to one of the devices…
- Trial name
- VOLIDO (NCT05386030)
- Testing
- saypha® VOLUME Lidocaine, Juvéderm® Voluma™ XC
- Where
- 16 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Multiple Sclerosis
Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial
The purpose of this trial is to evaluate the effects of Rebif® 44 mcg subcutaneous (sc) three times a week (tiw) on a) remyelination/demyelination, b) lesion and brain volume, c) central nervous system (CNS) iron deposition, and…
- Trial name
- NCT01085318
- Testing
- Rebif
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- EMD Serono
Volume Restoration and Shaping of the Buttocks
A Study to Evaluate Efficacy and Safety of Macrolane VRF30 for Volume Restoration and Contouring of the Buttocks
The purpose of the study is to evaluate the efficacy and safety of Macrolane for volume restoration and shaping of the buttocks.
- Trial name
- NCT01331408
- Testing
- Macrolane VRF30
- Where
- 4 sites in Belgium, Spain and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Correction of Nasolabial Folds
Observational Study to Evaluate Long-term Safety and Biodegradability of YVOIRE Volume s
To evaluate long-term safety of YVOIRE volume s by incidence of adverse events including injection site local reactions and biodegradability.
- Trial name
- NCT02661737
- Testing
- YVOIRE volume s
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Healthy Volunteer
Effects of Tradipitant on Satiation, Gastric Volume, Gastric Accommodation, and Gastric Emptying in Healthy Volunteers
To evaluate the effects of tradipitant relative to placebo on satiation, gastric volume, gastric accommodation, and gastric emptying in healthy volunteers.
- Trial name
- NCT04849559
- Testing
- Tradipitant
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Glabellar Frown Lines
Efficacy and Safety of a New Dilution and Injection Volume of AbobotulinumtoxinA for the Treatment of Glabellar Lines
An interventional phase 3 study to evaluate efficacy and safety of a new dilution and injection volume of AbobotulinumtoxinA treatment for glabellar lines
- Trial name
- NCT03960957
- Testing
- AbobotulinumtoxinA
- Where
- 11 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Blood Loss
Evaluation of the Zynex Blood Volume Monitor in Healthy Adult Patients During a Blood Draw
Non-invasive monitoring to measure changes in blood volume.
- Trial name
- NCT01846195
- Testing
- CM 1500
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zynex Monitoring Solutions
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to improve quadriceps strength…
- Trial name
- PBFR2 (NCT01440972)
- Testing
- partial blood flow restriction (PBFR), low intensity resistance training
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Volume Loss of the Jawline
Evaluation of the MJGS Following Radiesse (+) Injection Into the Jawline
This study will evaluate the sensitivity of the validated Merz Jawline Grading Scale (MJGS) to detect treatment effects following Radiesse (+) correction of subcutaneous volume loss and contour deficits of the jawline.
- Trial name
- NCT02904057
- Testing
- Radiesse (+) Injectable Implant
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Breast Diseases
Lesion Detection of Automated Breast Ultrasound Compared With Handheld Physician-performed Breast Ultrasound
Compare lesion detection of the automated breast ultrasound (ABVS) exam with the conventional handheld (HH) breast ultrasound (US) exam.
- Trial name
- NCT02310776
- Testing
- Supine automated breast ultrasound scanner, High-resolution handheld breast ultrasound
- Where
- 2 sites in United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Wrinkles in Decolletage
An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
This is a prospective open-label study to evaluate safety and effectiveness of two different reconstitution volumes of poly-l-lactic acid (PLLA) for correction of wrinkles in the décolletage area.
- Trial name
- NCT05538728
- Testing
- poly-l-lactic acid (Sculptra)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Volume Loss in the Dorsum of the Hand
Radiological Evaluation of Radiesse Implantation in the Hands
The objective of this study is to provide a preliminary assessment of the radiographic appearance of Radiesse material that has been injected into the dorsum of the hands.
- Trial name
- NCT02949921
- Testing
- Radiesse injectable implant and 2% lidocaine HCL
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Aging
Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation
Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues.
- Trial name
- NCT00956020
- Testing
- Platelet rich fibrin matrix
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Cheek Augmentation, Correction of Age-related Midface Contour Deficiencies
RHA®4 for Midface Volume Deficiency
This is a prospective, randomized, controlled, blinded evaluator, multicenter, between subjects clinical study to identify whether RHA4 is non-inferior to a comparator device for treatment of midface volume deficiency 8 weeks…
- Trial name
- NCT05133739
- Testing
- injection of RHA®4 in Midface, injection of Comparator Product in Midface
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Spontaneous Ventilation
EIT Assessment of Lung Volume and Tidal Distribution: A Comparison of Non-Invasive Ventilation Devices
This study is being done to further the investigators' knowledge of the EIT system and to see if measures between two non-invasive ventilation systems routinely used clinically are equivalent.
- Trial name
- NCT02930174
- Testing
- noninvasive positive pressure ventilation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Abnormal Lip
Study to Evaluate the Effectiveness, Safety and Long Term Safety of Saypha® FILLER Lidocaine for Lip Augmentation
This is a prospective, open-label, multicentre, randomized study conducted to evaluate the effectiveness, safety and long-term safety of Saypha® FILLER Lidocaine for lip augmentation.
- Trial name
- SayLip (NCT04917588)
- Testing
- Saypha® FILLER Lidocaine (HQ), Saypha® FILLER Lidocaine (C1)
- Where
- 3 sites in Austria
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Healthy Adult Volunteers
Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®)
Respiratory distress is a common problem in an intensive care unit. There are multiple mechanisms that are used to help patients who are in respiratory distress including mechanical ventilation, continuous positive airway…
- Trial name
- NCT01672242
- Testing
- HFNC, CPAP
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pulmonary Arterial Hypertension
Assessmet of Patients With PAH Right Ventricular Volume
The primary endpoint of this study is the percent difference between the VentriPoint Medical System (VMS) and cMRI for estimating the end diastolic and end systolic right ventricular volumes (RVEDV and RVESV) in subjects with…
- Trial name
- NCT01557582
- Testing
- Ventripoint Medical System
- Where
- 7 sites in United States, Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VentriPoint Diagnostics Ltd.
Conjunctival Staining
Defining the Conjunctival Staining Method: Instillation Volume and Time Course to Assess Staining With Lissamine Green
The purpose of this study is to determine the correct volume of lissamine green to use when assessing conjunctival staining, and to determine the time course needed to evaluate conjunctival staining after lissamine green has been…
- Trial name
- NCT00768898
- Testing
- 2.5/5.0/10.0 µL lissamine green
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alcon Research