Clinical trials: Vomiting
Chemotherapy-Induced Nausea and Vomiting (CINV)
Evaluating the Feasibility and Acceptability of Inhalation Aromatherapy for Patients Undergoing Autologous Haematopoietic Stem Cell Transplant (HSCT)
The goal of this clinical trial is to evaluate whether aromatherapy inhaler sticks can reduce nausea and vomiting in patients receiving chemotherapy as part of their stem cell transplant treatment.
- Trial name
- Aroma-CINV (NCT07209501)
- Testing
- Aromatherapy inhaler
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore General Hospital
Postoperative Complications, Postoperative Nausea and Vomiting
Electrical Acupoint Stimulation for Postoperative Recovery
This study investigates electrical acupoint stimulation (EAS) administered in peri-operation for improving postoperative recovery in elder patients, who accept knee arthroplasty.
- Conditions
- Postoperative Complications, Postoperative Nausea and Vomiting, Postoperative Infection, Postoperative Delirium
- Trial name
- EAS (NCT03249701)
- Testing
- Transcutaneous Electrical Acupoint Stimulation, Electroacupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shandong University of Traditional Chinese Medicine
Thyroidectomy, Thyroid Diseases
Preoperative Single-dose Steroid Application for the Treatment of Nausea and Vomiting After Thyroid Surgery
The study is to compare the postoperative recovery, as determined by postoperative nausea and vomiting (PONV) after preoperative application of single-dose dexamethasone versus saline in patients undergoing partial or total…
- Trial name
- tPONV (NCT01189292)
- Testing
- Dexamethasone, NaCl 0.9%
- Where
- Switzerland
- Volunteers
- 152 people
- Sponsor
- Cantonal Hospital of St. Gallen
Pelvic Organ Prolapse, PONV
Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
The investigators hypothesize that preoperative administration of 8 mg IV dexamethasone will benefit patients' perceived quality of recovery after surgery.
- Trial name
- NCT02073734
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- TriHealth Inc.
Emesis
Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human Volunteers
The main goal of this study is to develop a new oro-dissolvable/dispersible tablet that will augment the dual rapid absorption of MCZ from the buccal cavity as well as prolonging that from the GIT.
- Trial name
- NCT04564144
- Testing
- Meclizine Hydrochloride
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Total Knee Arthroplasty
Oral Carbohydrate in DM Patients Undergoing Total Knee Arthroplasty
The primary purpose of this study is to investigate the effects of carbohydrate-rich drink on postoperative nausea and vomiting in diabetic patients undergoing total knee arthroplasty.
- Trial name
- NCT02432781
- Testing
- Carbohydrate-rich drink, 10% dextrose solution mixed with insulin 16 unit 100 mL/h
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Severance Hospital
Nausea and Vomiting
the Efficacy and Safety of Ondansetron Oral Soluble Pellicles
The name of this prospective study is a multicenter, open-label, randomized controlled clinical study of the efficacy and safety of Ondansetron Oral Soluble Pellicles for the prevention of delayed nausea and vomiting induced by…
- Trial name
- NCT06282211
- Testing
- Ondansetron Oral Soluble Pellicles
- Where
- China
- Volunteers
- 184 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Chemotherapy-induced Nausea and Vomiting
Aprepitant ,Olanzapine,Palonosetron and Dexamethasone for the Prevention of Chemotherapy-induced Nausea and Vomiting
The purpose of the study is to mainly evaluate the efficacy and safety of aprepitant in combination with olanzapine ,palonosetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients…
- Trial name
- AOPDPCINV (NCT02484911)
- Testing
- Olanzapine, Aprepitant, Palonosetron
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Hematopoietic/Lymphoid Cancer, Nausea and Vomiting
Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy
This randomized phase III trial studies antiemetic therapy with olanzapine to see how well they work compared to antiemetic therapy alone in preventing chemotherapy-induced nausea and vomiting in patients with cancer receiving…
- Conditions
- Hematopoietic/Lymphoid Cancer, Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT02116530
- Testing
- Olanzapine, Chemotherapy (cisplatin or cyclophosphamide and doxorubicin), Antiemetic treatment (ondansetron or granisetron or palonosetron; plus dexamethasone; plus fosaprepitant or aprepitant)
- Where
- 177 sites in United States
- Volunteers
- 401 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pregnancy Emesis, Nausea
Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting
This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during…
- Trial name
- NCT07378839
- Testing
- Alternate Nostril Breathing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Neoplasms, Chemotherapy-induced Nausea and Vomiting
Serious Gaming for Chemotherapy-induced Nausea and Vomiting
The purpose of this study is to examine the effectiveness of a technology-based intervention for managing nausea and vomiting in older adults with cancer.
- Trial name
- NCT05838638
- Testing
- eSSET-CINV
- Where
- 2 sites in United States
- Volunteers
- 610 people
- Sponsor
- University of Central Florida
Terminal Illness
Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient
A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively.
- Trial name
- NCT04378998
- Testing
- Acupuncture
- Volunteers
- 136 people
- Sponsor
- University of Aarhus
Postoperative Nausea and Vomiting
Phase II Dose-ranging Study of APD421 in PONV
To assess the efficacy and safety of different doses of APD421 in the prevention of post-operative nausea and vomiting (PONV) in adult patients at moderate to high-risk of PONV.
- Trial name
- NCT01510704
- Testing
- APD421
- Where
- 13 sites in United States, France and 1 more
- Volunteers
- 215 people
- Sponsor
- Acacia Pharma Ltd
Dyspepsia
The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.
"Functional dyspepsia" has been defined loosely as "pain or discomfort centered in the upper abdomen." The symptoms can also include fullness, early satiety, bloating, belching, nausea, retching and vomiting.
- Trial name
- NCT00303264
- Testing
- dexloxiglumide, Nexium (esomeprazole)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Forest Laboratories
Breast Neoplasms
Chinese Herbal Acupoint Application Combined With Triple Antiemetic Therapy for Prevention of Chemotherapy-Induced Nausea and Vomiting in Breast Cancer
The goal of this clinical trial is to learn whether Chinese herbal acupoint application, when added to standard three-drug anti-nausea treatment, can prevent nausea and vomiting caused by chemotherapy in people with breast…
- Trial name
- NCT07848984
- Testing
- Chinese Herbal Acupoint Application, Standard Triple Antiemetic Therapy
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Nausea
Aprepitant for Post-operative Nausea
Anesthesia, especially for laparoscopic surgery, can cause post-operative nausea and vomiting. Most patients are given two drugs, decadron and ondansetron, to try to minimize this.
- Trial name
- NCT01020903
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwell Health
Nausea and Vomiting Caused by Chemotherapy
Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Gemcitabine Combined With Paclitaxel Protein-bound
This study aims to evaluate whether the preventive and suppressive effects of auricular point stimulation combined with dexamethasone on nausea and vomiting induced by the gemcitabine plus paclitaxel protein-bound regimen are…
- Trial name
- ADGP Ⅱ (NCT07716228)
- Testing
- Auricular point stimulation plus dexamethasone, Standard pharmacologic antiemetic regimen
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chemotherapy-induced Nausea and Vomiting
Evaluation of Predictive Risk Factors of Chemotherapy-induced Nausea and Vomiting
The most common toxicity of chemotherapy is nausea and vomiting, and appropriate management of these toxicities can help patients improve tolerance for chemotherapy.
- Trial name
- NCT01993381
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Postoperative Nausea and Vomiting
Granisetron Transdermal Patch for Prevention of Postoperative Nausea and Vomiting
The objective of the study is to evaluate the efficacy and safety of adding transdermal preparation of granisetron (Sancuso ®) to the current postoperative nausea and vomiting (PONV) standard prophylaxis regimen with…
- Trial name
- GTPPONV (NCT02457195)
- Testing
- granisetron
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Vomiting, Postoperative Nausea
Prophylaxis of Postoperative Nausea and Vomiting After Cardiac Surgery
To investigate the role of postoperative nausea and vomiting risk factors assessment after cardiac surgery. We designed a randomized controlled study comparing standard care (no risk factor assessment and no intervention) with…
- Conditions
- Postoperative Vomiting, Postoperative Nausea, Postoperative Emesis
- Trial name
- PONVACS (NCT02744495)
- Testing
- Betamethasone, Droperidol
- Where
- France
- Volunteers
- 502 people
- Sponsor
- Hôpital Privé de Parly II - Le Chesnay