Clinical trials: Vomiting, open to volunteers
Lumbar Degenerative Disease
Erector Spinae Plan Block (ESPB) with Dexmedetomidine and Dexamethasone in Lumbar Spine Fusion
This study wants to understand if using a pre-operative anesthetic injection could contribute to better pain relief after the surgery. This injection is referred to as an erector spinae plane block (ESPB, or "Block" for short).
- Trial name
- ESPB (NCT06658054)
- Testing
- Adjuvant analgesia, Control (Standard treatment)
- Volunteers
- 46 people
- Sponsor
- University of Southern California
Intradialytic Nausea and Vomiting, Chronic Kidney Disease
Manual Acupuncture for Intradialytic Nausea and Vomiting in Patients Undergoing Hemodialysis
This study aims to evaluate the immediate effects of acupuncture therapy at three specific acupuncture points (PC6, ST36, and KI3) on intradialysis nausea and vomiting in patients with chronic kidney disease undergoing regular…
- Conditions
- Intradialytic Nausea and Vomiting, Chronic Kidney Disease, Acupuncture
- Trial name
- NCT07888777
- Testing
- Acupuncture
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Menstrual Cycle, Optic Nerve Sheath Diameter
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery.
- Conditions
- Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
- Trial name
- NCT07539831
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Pain, Acute Post-Operative, Nausea and Vomiting, Postoperative
Catheter Redosing of Autonomic Neural Blockade After Sleeve Gastrectomy
Postoperative visceral pain and autonomic symptoms after laparoscopic sleeve gastrectomy may reappear earlier in selected high-risk patients despite standard intraoperative autonomic neural blockade (ANB).
- Trial name
- NCT07655908
- Testing
- Bupivacaine 0.5% and Dexamethasone via Temporary Catheter
- Volunteers
- 30 people
- Sponsor
- Universidad Simón Bolívar
Ventral Hernia, Postoperative Pain
Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations
The aim of this study is to compare the postoperative analgesic efficacy of bilateral erector spinae plane block and bilateral external oblique-intercostal plane block in patients undergoing open ventral hernia repair.
- Conditions
- Ventral Hernia, Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT07163026
- Testing
- Erector Spine Plane Block, External Oblique - Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
PONV
Sugammadex Reduces Antiemetic Effect of Dexamethasone
Sugammadex is a medication used for reversal of muscle relaxation during procedures under general anesthesia. It works by encapsulating muscle relaxant molecules with a steroid ring in its structure.
- Trial name
- NCT06901596
- Volunteers
- 100 people
- Sponsor
- Augusta University
Chronic Nausea, Chronic Nausea and Vomiting Syndrome
Evaluating Whether a Nausea Band Reduces Symptoms in Those With Chronic Nausea Vomiting
The goal of this clinical trial is to learn whether a wearable transcutaneous electrical nerve stimulation (TENS) device called EmeTerm can help reduce nausea in adults who have had nausea for 2 months or longer and who receive…
- Trial name
- WINNER (NCT07720323)
- Testing
- EmeTerm wearable TENS device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University
Chemotherapy Induced Nausea and Vomiting
Olanzapine Versus Placebo for Moderately Emetogenic Chemotherapy
A study comparing efficacy of olanzapine versus placebo to prevent nausea and vomiting from moderate emetic risk chemotherapy
- Trial name
- NCT06850454
- Testing
- olanzapine
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Mahidol University
Hematological Malignancies
Efficacy of Inhaled Aromatherapy on Nausea and Vomiting in Hematological Malignancies
This project will optimise the management of chemotherapy-induced nausea and vomiting, with improvements in nausea and vomiting scores, quality of life and appetite expected in participants benefiting from the intervention.
- Trial name
- AROM-HEMATO (NCT06150469)
- Testing
- "Blend of ginger and lemon essential oils", "Neutral oil"
- Where
- 4 sites in France
- Volunteers
- 286 people
- Sponsor
- University Hospital, Limoges
Nausea and Vomiting Caused by Trastuzumab Deruxtecan
Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Trastuzumab Deruxtecan
The goal of this clinical trial is to learn if auricular point stimulation plus dexamethasone works to effectively prevent or suppress nausea and vomiting caused by trastuzumab deruxtecan in breast cancer palliative therapy.
- Trial name
- ADTD (NCT07537673)
- Testing
- Auricular point stimulation plus dexamethasone
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chemotherapy Induced Nausea and Vomiting
Dolasetron for the Prevention of CINV in Children With Acute Lymphoblastic Leukemia
This is a prospective, multicenter, real-world study of 500 participants with childhood acute lymphoblastic leukemia who are scheduled to receive dolasetron mesylate injection for prophylaxis against chemotherapy-induced nausea…
- Trial name
- NCT06756022
- Testing
- Dolasetron mesylate injection
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Anhui Provincial Children's Hospital
Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative
Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study
After surgery, doctors need to know how patients are doing, especially in the first hours after they leave the recovery room. This can be hard to track once patients go to a regular hospital room, and some symptoms - like pain or…
- Conditions
- Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative, Postoperative Nausea and Vomiting, Recovery of Function (G11.427.698.620)
- Trial name
- NCT07794267
- Testing
- Digital web-based postoperative follow-up form
- Where
- Brazil
- Volunteers
- 213 people
- Sponsor
- Hospital de Base
Postoperative Nausea and Vomiting (PONV), Postoperative Pain
Effect of Timing of Dexamethasone During Induction on Postoperative Outcomes
This study aims to investigate how the timing of dexamethasone administration during anesthesia induction affects patient outcomes after surgery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Postoperative Pain, Inflammatory Response to Wounding, Hyperglycemia Drug Induced
- Trial name
- TIDE (NCT06685991)
- Testing
- Dexamethasone
- Volunteers
- 300 people
- Sponsor
- AABDI Mohammed
Caudal Anesthesia
Preventative Effect of Combining Dexamethasone with Ondansetron on Postoperative Nausea, Vomiting and Shivering in Children Undergoing Caudal Anesthesia on Hypospadias Surgery
caudal epidural block is a technique used as an adjuvant to general anesthesia for postoperative analgesia in pediatric patients,especially those with infraumbilical, perineal and lower extremity surgery , because it reduces the…
- Trial name
- NCT06747975
- Testing
- Dexamethasone and Ondansetron, Bupivacaine + saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sedation, Cataract
Dexmedetomidine and Propofol for Sedation in Cataract Surgery.
The goal of this prospective, randomized, single-blinded is to learn if there is an ideal sedation protocol in cataract surgery in adults.
- Conditions
- Sedation, Cataract, Hemodynamic, Hemodynamic Changes
- Trial name
- NCT07556133
- Testing
- Dexmedetomidine (DEX), Propofol (PRO), Fentanyl (FEN)
- Where
- Lebanon
- Volunteers
- 1,000 people
- Sponsor
- Saint-Joseph University
Pancreatic Cancer Stage IV, Chemotherapy-induced Nausea and Vomiting
Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of thalidomide on improving the quality of life for metastatic pancreatic cancer patients receiving gemcitabine and nab-paclitaxel chemotherapy.
- Trial name
- PTCA199-5 (NCT06017284)
- Testing
- Thalidomide, Nab paclitaxel, Gemcitabine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
PONV
Effect of Lidocaine Through Gastric Tube on PONV
The goal of this clinical trial is to learn if intragastric administration of lidocaine can reduce postoperative nausea and vomiting in obese patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- NCT07643298
- Testing
- Lidocaine, Normal Saline (0.9% NaCl)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Breast Cancer, Aromatherapy
Aromatherapy Combined With Standard Antiemetic Therapy vs Standard Therapy Alone for Prevention of CINV in Breast Cancer Patients Receiving Highly Emetogenic Chemotherapy
This phase III, multicenter, randomized, open-label trial evaluates whether aromatherapy plus standard antiemetic therapy improves complete response (CR) of CINV compared with standard therapy alone in breast cancer patients…
- Conditions
- Breast Cancer, Aromatherapy, Chemotherapy, CINV
- Trial name
- NCT07761325
- Testing
- Aromatherapy, Standard triple antiemetic therapy
- Volunteers
- 374 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University