Clinical trials: Vulvar Vestibulitis, active
Vestibulodynia, Vulvodynia
Integrated Care Pathway for Hormonally Mediated Vestibulodynia: a Feasibility and Acceptability Pilot
This single-arm pilot study evaluates whether an integrated six-month care pathway for women with persistent vestibular vulvar pain and suspected hormonally mediated vestibulodynia can be delivered as planned, and how…
- Conditions
- Vestibulodynia, Vulvodynia, Vulvar Vestibulitis
- Trial name
- HerAccess (NCT07908901)
- Testing
- HerAccess integrated care pathway
- Where
- 2 sites in Denmark
- Volunteers
- 35 people
- Sponsor
- HerAccess ApS
Provoked Vestibulodynia, Secondary Provoked Vestibulodynia
Topical Ketotifen 0.25% for Secondary Vestibulodynia
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of topical ketotifen fumarate 0.25% cream in adult women with secondary provoked vestibulodynia (PVD).
- Conditions
- Provoked Vestibulodynia, Secondary Provoked Vestibulodynia, Vulvodynia, Vulvary Pain Disorders
- Trial name
- NCT07257029
- Testing
- Ketotifen Fumarate 0.25% Cream
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Center for Vulvovaginal Disorders
Provoked Vestibulodynia
IncobotulinumtoxinA for Provoked Vestibulodynia With Overactive Pelvic Floor Muscle Dysfunction
This is a double-blind, placebo-controlled study evaluating the safety and efficacy of incobotulinumtoxinA (Merz) for the treatment of provoked vestibulodynia (PVD) associated with overactive pelvic floor muscle dysfunction.
- Trial name
- NCT07486830
- Testing
- Incobotulinum Toxin A
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Center for Vulvovaginal Disorders
Provoked Vestibulodynia
Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse
Chronic vulvar pain is a highly prevalent and debilitating condition affecting up to 16% of women. The most common subtype of vulvar pain, provoked vestibulodynia (PVD), is characterized by a sharp pain at the entry of the vagina…
- Trial name
- NCT07534345
- Testing
- Real dry needling
- Where
- 4 sites in Canada
- Volunteers
- 170 people
- Sponsor
- Université de Sherbrooke
Vulvodynia
A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia)
The study (IP2015CS05) is a randomised, double-blind, placebo-controlled, 4-way cross-over trial studying the efficacy and safety of single dose administration of pudafensine in vulvodynia (provoked vestibulodynia) patients.
- Trial name
- NCT07391241
- Testing
- Pudafensine
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Initiator Pharma
Dyspareunia (Female)
Rigid Hymenal Ring as a Cause for Insertional Dyspareunia
Given the frequently observed rigid hymenal ring as a cause of insertional dyspareunia as well as the resolution of pain (including posterior vestibulodynia) following its targeted therapy, the study aims to describe its…
- Trial name
- NCT07913386
- Testing
- Hymenectomy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Vulvodynia, Provoked Vestibulodynia
Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health
This trial will provide evidence for the effective management of pain and pain-related domains among those who experience provoked vestibulodynia (PVD) using photobiomodulation (PBM) and multimodal physiotherapy (mPT) in a…
- Conditions
- Vulvodynia, Provoked Vestibulodynia, Dyspareunia
- Trial name
- BRIGHT (NCT06660212)
- Testing
- Photobiomodulation, Multimodal physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Ottawa
Vestibulodynia (VBD), Vulvodynia
Vestibulodynia At High Resolution: Omics Approach to Improve Diagnosis
According to recent nomenclature, vulvodynia is vulvar pain without a clear identifiable cause persisting for at least 3-months and distinguished from vulvar pain caused by a specific disorder (inflammatory, neoplastic…
- Trial name
- NCT06865963
- Testing
- vulvar biopsy and blood semples
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis
Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?
The goal of this clinical trial is to learn if a 3-month online pelvic health program works to improve pain and sexual wellbeing in adult women with chronic genital pain.
- Conditions
- Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis, Vestibulodynia, Provoked Vestibulodynia
- Trial name
- PVD (NCT06999395)
- Testing
- Virtual online pelvic health program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Queen's University
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute