Clinical trials: Vulvodynia
Vestibulodynia (VBD) From at Least 6 Months
Ultrasound Evaluation and Vestibular Perception Thresholds Changes in Women Affected by Vestibulodynia (VBD) After One Cycle of Pixel CO2-Alma Fractionated Laser
Vestibulodynia (VBD), term revised by Consensus Terminology and Classification of Persistent Vulvar Pain and Vulvodynia in 2015, is a vulvar pain of at least 3 months' duration, without clear identifiable cause and localized at…
- Trial name
- NCT05156489
- Testing
- Fractionated Laser (Pixel CO2-Alma)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Chronic Urogenital Pain
Life-Stress Interview for Women With Chronic Urogenital Pain Conditions
The goal of this study is to test the efficacy, feasibility, and acceptability of providing an experiential assessment interview that targets health, and emotional and stressful experiences in a tertiary care setting specializing…
- Trial name
- NCT02286115
- Testing
- Life-Stress Interview
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Corewell Health East
Vulvodynia, Naltrexone
Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia
Vulvodynia (Vd) is chronic functional vulvar pain, with prevalence of 3-16% and unclear etiopathology. Although Vd significantly deteriorates quality of life, the problem is marginalized, no pharmacologic treatment standards…
- Conditions
- Vulvodynia, Naltrexone, Quality of Life
- Trial name
- NCT05955313
- Testing
- Naltrexone Hydrochloride
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Lublin
Vulvodynia, Dyspareunia
Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia
Chronic pain problems involving the female reproductive system are major health concerns for all women. Poorly understood, they entail great personal and financial cost.
- Conditions
- Vulvodynia, Dyspareunia, Vestibulodynia
- Trial name
- CBCT-RCT (NCT01935063)
- Testing
- Cognitive Behavioral Couple Therapy, Topical Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Université de Montréal
Vulvodynia
The Effectiveness of Vestibulectomy
Women with vulvodynia will fill out a questionnaire and undergo a gynecological examination before and 6 months after vestibulectomy. The investigators hypothesize that pain will decrease.
- Trial name
- NCT00873301
- Testing
- vestibulectomy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Western Galilee Hospital-Nahariya
Vulvodynia
CC-10004 For The Treatment Of Vulvodynia
Vulvodynia is characterized by persistent vulvar pain, which often occurs upon touch or pressure. The cause of vulvodynia is unknown but is presumed to involve many factors.
- Trial name
- NCT00814632
- Testing
- CC-10004
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kenneth Peters, MD
Provoked Localized Vulvodynia
M-gCBT for Women With Provoked Localized Vulvodynia
The purpose of this study is to learn more about Mindfulness based Group Cognitive Behavior Therapy (M-gCBT) as a treatment for Provoked Localized Vulvodynia (PLV).
- Trial name
- NCT02919813
- Testing
- Mindfulness Based Group Cognitive BehaviorTherapy, Educational Seminars
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Health and Science University
Vulvodynia
Efficacy of High Intensity Laser for Provoked Vestibulodynia
This is a multicenter randomized controlled trial (RCT) investigating the effects of laser treatments in women suffering from provoked vestibulodynia compared to a sham-laser treatment.
- Trial name
- Laser_RCT (NCT05597358)
- Testing
- High Intensity Laser Therapy (HILT)
- Where
- 4 sites in Canada
- Volunteers
- 145 people
- Sponsor
- Université de Sherbrooke
Vulvodynia
Vulvodynia Pain Thresholds
Annotated pain maps will be created showing region and size of areas sensitive to mechanical stimulus in both women affected by vulvar pain and unaffected control patients.
- Trial name
- NCT04461210
- Testing
- Thermographic Imaging and Mechanical Pain Assessment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Painful Bladder Syndrome, Interstitial Cystitis
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Purpose: 1. To demonstrate better symptoms control (pain, urinary urgency and frequency) with sacral neuromodulation (SNM) in patients with interstitial cystitis /painful bladder syndrome (IC/PBS) using a stimulation frequency of…
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction
- Trial name
- NCT01312259
- Testing
- Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Pelvic and Sexual Health Institute
Vulvodynia
Young Vulvodynia: Effect and Efficacy of Multimodal Treatment.
The aim of this SCED-study is to evaluate a multimodal treatment for vulvodynia in young women. The main questions it aims to answer are: Is multimodal treatment effective for provoked vulvodynia in young women? How is multimodal…
- Trial name
- UV (NCT07092332)
- Testing
- Multimodal treatment
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Region Örebro County
Vulvodynia, Vulvar Vestibulitis
A Search for Helicobacter Pylori in Localized Vulvodynia
Hypothesis: to examine a possible association between localized vulvodynia and H. pylori infection.
- Trial name
- NCT00501774
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- Western Galilee Hospital-Nahariya
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Interstitial Cystitis
Relationship of Interstitial Cystitis to Vulvodynia
This study is important in urologic nursing since many patients have interstitial cystitis (IC), a condition of frequency, urgency and pain affecting more than 1 million women in the United States.
- Trial name
- NCT00546858
- Testing
- Physical Examination
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Corewell Health East
Localized Provoked Vulvodynia
Infiltration of the Vestibulum Vaginae With Botulin Toxin in Patients With Localized Provoked Vulvodynia
In this study we will investigate the efficacy and safety of infiltration of the vestibulum vaginae with botulin toxin in women who were diagnosed with localized provoked vulvodynia.
- Trial name
- VVS-01 (NCT01747161)
- Testing
- Botulin toxin, physiological water
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- University Hospital, Ghent
Vestibulodynia
Efficacy of a Physiotherapy Treatment in Women Suffering From Provoked Vestibulodynia
Chronic gynaecological pain is a major medical problem that affects 20-30% of women at different moments of their life. This largely neglected issue has a significant impact on the sexual and conjugal life of women suffering from…
- Trial name
- NCT01455350
- Testing
- Multimodal physiotherapy, lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 212 people
- Sponsor
- Université de Sherbrooke
Vulvodynia
Profiling Vulvodynia Based on Neurobiological and Behavioral Endophenotypes
The investigators plan to extensively phenotype a large sample of Vulvodynia (VD) patients using functional and structural brain imaging together with genetic, physiological, and biological parameters.
- Trial name
- Vulvodynia (NCT02733172)
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of California, Los Angeles
Vulvodynia, Vulvar Vestibulitis
Pregabalin for the Treatment of Vulvodynia
The purpose of this study is to determine whether pregabalin is effective in the treatment of vulvodynia.
- Trial name
- NCT00853229
- Testing
- pregabalin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Vulvodynia
A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized Vulvodynia
In order to investigate whether the pain in women with vulvodynia may represent bladder origin pain, we will be performing a diagnostic test for interstitial cystitis (IC) in women with generalized vulvodynia.
- Trial name
- VV/IC (NCT01048177)
- Testing
- Bladder instillation with heparin/ lidocaine
- Where
- United States
- Sponsor
- Scripps Health
Provoked Localized Vulvodynia
Subtypes of Provoked Vestibulodynia
The proposed study will evaluate a clinical algorithm for the diagnosis and treatment of provoked vestibulodynia (PVD). The algorithm, distinguishes between four subtypes of PVD: hormonally mediated PVD, hypertonic pelvic floor…
- Trial name
- NCT02712814
- Testing
- Topical hormonal cream (estrogen), Pelvic floor physical therapy, Low Level Laser therapy
- Where
- Israel
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center