Clinical trials: WOUNDS INJURIES
Brain Damage, Postoperative Cognitive Dysfunction
Liver Transplant Does it Affect the Brain
Neuronal damage caused by neuroinflammation in patients undergoing major surgery is the most determinant factor of postoperative cognitive disfunction (POCD).
- Conditions
- Brain Damage, Postoperative Cognitive Dysfunction, Neuron Specific Enolase, Glial Fibrillary Acidic Protein
- Trial name
- NCT04368052
- Testing
- Mini Mental Test (MMT), S-100 beta, Neuron specific enolase and Glial fibrillary acidic protein
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Ege University
Anterior Cruciate Ligament Injury, Postoperative Pain
Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction
The study aims to investigate the effect of the popliteal plexus block (PPB) on postoperative pain in patients undergoing anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT03130049
- Testing
- Popliteal plexus block
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Cerebellar Ataxia, Cerebellum; Injury
Effect of ctDCS During Balance Training on Cerebellar Ataxia
Cerebellar ataxia is a neurologic symptom caused by damage or dysfunction in the cerebellum and its pathways that results in loss of coordination, balance and postural control.
- Conditions
- Cerebellar Ataxia, Cerebellum; Injury, Balance
- Trial name
- NCT04039048
- Testing
- cerebellar transcranial direct current stimulation, Balance training
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal de Pernambuco
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Trauma, Psychological; Somatic
Psychotraumatology in Somatic Medicine
Psychotraumatology is clinically highly relevant, especially in the medical-somatic disciplines. Despite progress in recent decades, the clinical care is still inadequate - with unfavorable health effects for affected patients.
- Trial name
- NCT05297435
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Cantonal Hospital of St. Gallen
Post Concussion Syndrome
mHealth Technology in the Treatment of Post-concussion Symptoms
Patients with concussion symptoms are asked by their doctors to stretch, exercise, and practice mindfulness daily. Patients can have a hard time sticking to these activities, which can cause patients to feel symptoms for longer…
- Trial name
- PERSIST (NCT05848193)
- Testing
- MyHeadHealth online application, Standard of Care
- Volunteers
- 88 people
- Sponsor
- McMaster University
Spinal Cord Injuries, Spinal Cord Diseases
Restoring Upright Mobility After Spinal Cord Injury
Up to 15 able-bodied individuals will participate in one testing session to evaluate the effectiveness of the A-FES system. Up to 20 individuals with SCI will participate in 12 sessions of A-FES therapy.
- Trial name
- NCT04262414
- Testing
- Functional Electrical Stimulation
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Hip Fracture, Aged
A New Clinical Pathway for Patients With Fractured Neck of Femur
The intention is to evaluate the effectiveness of a multi-factorial medical treatment of patients with hip fractures in a specially designed unit for elderly hip fracture patients (orthogeriatric unit) as compared to traditional…
- Trial name
- NCT00667914
- Testing
- geriatric work-up, Orthopedic care as usual
- Volunteers
- 397 people
- Sponsor
- Norwegian University of Science and Technology
Subarachnoid Hemorrhage, Severe Traumatic Brain Injury
Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever
When fever is present in patients with stroke, traumatic brain injury (TBI), or brain hemorrhage, it has been associated with worse outcomes including larger areas of tissue death, increased length of stay, worse degree of coma…
- Trial name
- SNIF (NCT00890604)
- Testing
- Stepwise normothermia protocol, Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Death, Sudden, Cardiac, Electrocardiogram QT Prolonged
Risk of Sudden Cardiac Death in UN Athletes
The detection of sudden cardiac death risk in athletes is a topic of great relevance in the field of sports physiotherapy and physical activity.
- Conditions
- Death, Sudden, Cardiac, Electrocardiogram QT Prolonged, Athlete Heart, Athletic Injuries
- Trial name
- Suddendeath (NCT06518252)
- Where
- Colombia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Spinal Cord Injuries, Respiration Disorders
Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury
Respiratory complications are among the leading causes of death in patients with chronic spinal cord injury (SCI). Our previous work showed that pulmonary function can be improved by using our original respiratory training…
- Trial name
- NCT06019949
- Testing
- Transcutaneous spinal cord stimulator, Respiratory Training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Hydrocephalus in Children, Epilepsy
Myelin Imaging Changes In Patients With Neurosurgical Diseases
Investigate myelin alterations in patients with neurosurgical diseases
- Conditions
- Hydrocephalus in Children, Epilepsy, Craniosynostoses, Traumatic Brain Injury
- Trial name
- McDESPOT (NCT03698838)
- Testing
- McDESPOT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Healthcare System
Postoperative Vocal Cord Mobility, Recurrent Laryngeal Nerve Injury
C-MAC D-Blade vs Macintosh for Postoperative Vocal Cord Evaluation
This study compares two different laryngoscopes-the C-MAC D-Blade videolaryngoscope and the Macintosh direct laryngoscope-for evaluating vocal cord mobility after thyroidectomy.
- Trial name
- NCT07277985
- Testing
- Videolaryngoscope (C-MAC D-Blade), Direct Laryngoscope (Macintosh)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Ankle Fractures
Diabetic Fibular Nail Study
Our null hypothesis is that fibular intramedullary fixation (IMFN) does not impact complication rates when compared to standard of care treatment with open reduction and internal fixation (ORIF).
- Trial name
- NCT05204485
- Testing
- Fibular intramedullary nail, Open reduction and internal fixation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Chicago
Spinal Cord Injury, ALS (Amyotrophic Lateral Sclerosis)
Clinical Outcome Assessment for AT & BCI
Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers.
- Trial name
- NCT07407725
- Testing
- Eye Tracker, Mouth Operated Joystick, Non-invasive electroencephalogram (EEG) Headset
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Traumatic Brain Injury, Pediatric
Age Related Thresholds for Management of Severe Head Injury in Paediatrics: An Extension of STARSHIP
Traumatic brain injury in children can cause serious and long-lasting neuro-disability. However, there is still limited evidence about the best ways to treat children with severe brain injury in intensive care.
- Conditions
- Traumatic Brain Injury, Pediatric, Cerebral Perfusion Pressure, Cerebral Autoregulation
- Trial name
- ARTSHIP (NCT07834476)
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Burns
Comparison of High Flow vs Standard Nasal Cannula in Children With Burns Under Sedoanalgesia
The aim of this study is to investigate the positive effects of high-flow oxygen therapy on the reduction of airway adverse events and recovery time compared to conventional nasal oxygen therapy in pediatric burns treated with…
- Trial name
- NCT06663293
- Testing
- Conventional Nasal Cannula, High-flow nasal cannula, midazolam, ketamine, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Zeliha Alicikus
Retinitis Pigmentosa, Maculopathy, Age Related
High Resolution, High-speed Multimodal Ophthalmic Imaging
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- IMA-MODE (NCT04129021)
- Testing
- High-resolution retinal imaging through adaptive optics, High-resolution retinal imaging through holographic systems
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Hand Injuries
Use of MoTrack Therapy in At-Home Hand Rehabilitation
This study focuses on the use of a specific type of at-home hand rehabilitation software, MoTrack Therapy, in improving the treatment of hand and wrist injuries.
- Trial name
- NCT03345693
- Testing
- MoTrack Therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Needlestick Injuries
Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?
This study will investigate the influence of adjusting the pH of lidocaine on pain during subcutaneous injection. Each participant will receive two injections on the abdomen with different pH.
- Trial name
- NCT02107716
- Testing
- Lidocaine injection with bicarbonate, lidocaine injection
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.