Clinical trials: WOUNDS INJURIES
Burn
Determining Elements of Anti-Fungal Immunity in BURN Patients
Scientific justification Invasive fungal diseases (IFDs) pose a substantial threat, especially in immunocompromised patients, necessitating urgent research focus and therapeutic advancements.
- Trial name
- DEFI-BURN (NCT06828458)
- Testing
- Biological sampling
- Where
- France
- Volunteers
- 327 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Locally Recurrent Head and Neck Cancer
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours
The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with…
- Trial name
- HyBT-H&N (NCT03238378)
- Testing
- Brachytherapy, Hyperthermia
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obstetric; Injury, Injury
Impact of Monitoring Quality Indicators in Maternity Departments on Mother and Infant Health
Hypothesis: Continuously monitor quality indicators with a specific method (CUSUM: Cumulative Sum) will increase the awareness of health care staff in maternity and permit rapid detection of a small dip in performance in order to…
- Trial name
- MATICUS (NCT01459978)
- Testing
- CUmulative SUM (CUSUM) Chart
- Where
- 2 sites in France
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Commotio Cerebri, Mild Traumatic Brain Injury
Get Going After concussioN 2.0
The study tests the promising results of a previous study (GAIN 1.0) in a larger RCT (GAIN 2.0) which takes place in the municipalities of Central Denmark Region where citizens live their daily lives and whose health- and social…
- Trial name
- GAIN2 (NCT04798885)
- Testing
- GAIN 2.0
- Where
- Denmark
- Volunteers
- 310 people
- Sponsor
- University of Aarhus
Lateral Epicondylitis, Tennis Elbow
Comparison of the Efficacy of Mesotherapy and Extracorporeal Shock Wave Therapy in Patients With Lateral Epicondylitis
The goal of this clinical trial is to investigate the efficacy of mesotherapy in patients with lateral epicondylitis and to determine whether it is as effective as extracorporeal shock wave therapy (ESWT).
- Trial name
- NCT07043335
- Testing
- Extracorporeal Shock Wave Therapy, Mesotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Foreign Bodies, Tumor
High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
- Conditions
- Foreign Bodies, Tumor, Stenosis Trachea, Bronchus Tumour
- Trial name
- NCT03892408
- Testing
- Optiflow ™
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Spinal Cord Injuries, Spinal Cord Diseases
PAS in Subacute SCI
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles.
- Trial name
- NCT04101916
- Testing
- Paired associative stimulation
- Where
- Finland
- Volunteers
- 18 people
- Sponsor
- Helsinki University Central Hospital
Injury;Sports
The Relationship of ACWR and FMS With Injury Risk in Adolescent Players
In this study, we examine how acute to chronic workload ratio and functional movement screen scores relate to injury risk in teenage athletes who play team sports.
- Trial name
- NCT06001216
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Intraoperative Complications, Thermal Injury
Laparoscopic Cholecystectomy And Capacitive Coupling - Coag Versus Blend Mode Causing Thermal Injury at Port Site Skin
Monopolar radiofrequency energy is used to perform the laparoscopic cholecystectomy operation. The appearance of burns are common following laparoscopic cholecystectomy; particularly at the port site of the active electrode.
- Conditions
- Intraoperative Complications, Thermal Injury, Electrocoagulation
- Trial name
- NCT01664806
- Testing
- Covidien Triad monopolar generator
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries
Comparison of Pilates &Home Exercise Programs on Muscle Strength in Paraplegic Patients
Paraplegic patients to be included in the study were divided into 2 groups by randomization and it was planned to apply reformer pilates or home exercise programs for 8 weeks.
- Trial name
- NCT04360447
- Testing
- Reformer Pilates, Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sports Injury
Effect of EMS and Strengthening Exercises on Pain, Fatigue and Physical Performance in Motocross Athletes
Motocross, a popular sport, involves riding motorized vehicles on rugged tracks with obstacles. It's physically demanding, with high speeds and a risk of accidents.
- Trial name
- NCT06300385
- Testing
- Electromyostimulation, Strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Breast Cancer, Cardiac Toxicity
Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, fluorouracil, epirubicin hydrochloride, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…
- Conditions
- Breast Cancer, Cardiac Toxicity, Perioperative/Postoperative Complications
- Trial name
- NCT01093235
- Testing
- bevacizumab, cyclophosphamide, docetaxel
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Brain Injury, Acute Lung Injury
Alveolar Recruitment in Brain Injury
Development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in patients with severe brain injury has been associated with poor outcome.
- Trial name
- NCT01159392
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Hospital Clinic of Barcelona
Lung Injury
Functional Residual Capacity and Alveolar Recruitment in Single-lung Ventilation: a Randomized Study
In thoracic surgery, the incidence of postoperative pulmonary complications is higher than for other surgeries. Indeed, thoracic surgery has the specificity of being carried out with single-lung ventilation and is thus a source…
- Trial name
- OLVEELV (NCT06446544)
- Testing
- VPFE monitoring with intraoperative alveolar recruitment maneuvers.
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Rouen
Multiple Trauma
Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients
The purpose of this study is to determine whether Erythropoietin decrease stress responses and inflammation in trauma patient.
- Trial name
- EPREX (NCT00622934)
- Testing
- erythropoietin
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Tehran University of Medical Sciences
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Femoral Fractures
Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in a number of types of surgery.
- Trial name
- NCT00824564
- Testing
- Tranexamic Acid plus standard of care, Standard of care
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Pfizer
SCLC, Limited Stage, Radiation Exposure
Omitting CTV for Primary Tumor in LS-SCLC
This randomized controlled non-inferior trial prospectively enrolled patients with limited-stage small cell lung cancer (LS-SCLC).
- Conditions
- SCLC, Limited Stage, Radiation Exposure, Radiotherapy Side Effect, Progression
- Trial name
- NCT07008716
- Testing
- Radiation Therapy, Etoposide + carboplatin; Etoposide + cisplatin, Creating CTV for primary tumor
- Where
- 2 sites in China
- Volunteers
- 852 people
- Sponsor
- Sun Yat-sen University
Traumatic Spinal Cord Injury, Tetraplegia/Tetraparesis
NIBS Therapy in Subacute Spinal Cord Injury
No accepted clinical therapies exist for repair of motor pathways following spinal cord injury (SCI) in humans, leaving permanent disability and devastating personal and socioeconomic cost.
- Trial name
- NIBS-SCI1 (NCT06247904)
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Albert Einstein Healthcare Network
Spinal Cord Injuries, Type 2 Diabetes
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
It is not known whether a new diabetes drug, semaglutide, is an effective treatment for type 2 diabetes for persons with spinal cord injury (SCI), a population at higher risk for this condition.
- Trial name
- NCT06706284
- Testing
- Semaglutide Injectable Product
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Marzieh Salehi
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