Clinical trials: WOUNDS INJURIES
Lung Injury
Inhibition of Plasma Kallikrein as a New Therapy for Lung Injury
Phase 1 study investigating safety of lanadelumab administration to patients with lung injury
- Trial name
- NCT04848272
- Testing
- Lanadelumab, Saline control
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- St Vincent's Institute of Medical Research
Infection, Hand Injury Wrist
Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration
The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (upper extremity) is more effective at preventing infection than the current standard dose…
- Conditions
- Infection, Hand Injury Wrist, Hand Injuries, Hand Injuries and Disorders
- Trial name
- NCT04673877
- Testing
- Systemic IV Vancomycin, Bier Block, Vancomycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Traumatic Brain Injury, Brain Injuries, Traumatic
Training Executive Functions to Facilitate Recovery Following Traumatic Brain Injury
The purpose of this research study is to investigate different types of task training to determine if training improves thinking processes following traumatic brain injury.
- Trial name
- NCT01993407
- Testing
- Task Switching Training, Control Task
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Postoperative Pain, Rotator Cuff Injuries
US-Guided Preemptive Brachial Plexus Blockade May Reduce Post-operative Pain: a Randomized Study
Intense e recurrent nociceptive stimulation, which occurs in the postoperatively, can trigger sensitization of the peripheral and central nociceptive pathway, leading to chronic pain.
- Trial name
- NCT04005534
- Testing
- Standard group, Preemptive group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Traumatic Brain Injury
Evaluation of Discriminating Power of Two Biomarkers in the Evaluation of Cerebral Lesions Due to Head Injuries in Infants and Children
Head injury is a frequent motive of consultation in paediatric emergency units and the first cause of mortality in infants of more than one year old in developped countries.
- Trial name
- TCOP100 (NCT02855034)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 167 people
- Sponsor
- University Hospital, Montpellier
Rotator Cuff Tears, Micro Fracture
Microfracture at Proximal Humerus Lateral to Footprint Could Enhance the Rotator Cuff Healing
The goal of this clinical trial is to test whether there is any effect on rotator cuff healing by making microfracture at the lateral side of the footprint.
- Trial name
- NCT05624164
- Testing
- Lateralised microfracture
- Where
- 2 sites in China
- Volunteers
- 88 people
- Sponsor
- Affiliated Hospital of Nantong University
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Distal Radius Fracture
Effects of Action Observation Therapy and Motor Imagery Administered During Immobilization Period After Surgical Fixation of Distal Radius
The goal of this trial is to verify the effectiveness of Motor Imagery and Action Observation Training in subjects undergoing surgery for distal radius fracture fixation.
- Trial name
- NCT05867199
- Testing
- Motor Imagery and Action Observation Training
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Athletic Injuries, Sport Injuries
Rise With Resilience
The objective of this study is to investigate differences in postoperative pain, physical health, and mental health outcomes between participants receiving evidence-based mindfulness training and those who do not.
- Trial name
- NCT07217275
- Testing
- Community Resiliency Model (CRM), Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Tooth Fractures
Immediate Implant Placement With Connective Tissue Graft or Socket Shield
The present study aims to evaluate the clinical outcomes of immediate implant placement with connective tissue graft or socket shield.
- Trial name
- NCT03594019
- Testing
- Connective tissue graft, socket shield technique, Immediate implant placement
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Wounds and Injuries
Does an International Version of ICISS Predict Mortality for Patients Admitted With Trauma in Four Public University Hospitals in Urban India?
The aim of this study is to validate international versions of the International Classification of Disease Injury Severity Score (ICISS) in adult trauma patients admitted to four public university hospitals in urban India.
- Trial name
- NCT02724007
- Volunteers
- 16,047 people
- Sponsor
- Martin Gerdin
Trauma (Including Fractures)
Characteristics of Bouldering Injuries in a Major Trauma Centre
Retrospective data collection in major trauma centre
- Trial name
- NCT07498036
- Where
- United Kingdom
- Volunteers
- 176 people
- Sponsor
- NHS Lothian
Pancreatic Trauma, Pancreatic Duct Injury
A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes
The goal of this observational study is to compare the presentation, treatment, and outcomes in patients suffering traumatic pancreatic injuries from blunt or penetrating trauma. The questions this study aims to answer are: 1.
- Conditions
- Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst
- Trial name
- NCT06227871
- Testing
- Exploratory laparotomy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kern Medical Center
Cancers, Cardiovascular Diseases
Swedish Mammography Cohort
The Swedish Mammography Cohort began in 1987-1990, when 66,651 women living in two counties in central Sweden completed a mailed questionnaire that included items about their diet, parity, age at first child's birth, history of…
- Conditions
- Cancers, Cardiovascular Diseases, Cataract, Gastrointestinal Diseases
- Trial name
- SMC (NCT01127698)
- Volunteers
- 61,433 people
- Sponsor
- Karolinska Institutet
Trauma
Beta Blockade in Critical Injury
Critically injured patients endure a period of hypermetabolism/catabolism after being resuscitated. The metabolic cost of this may be measured in loss of lean body mass, poor wound healing, susceptibility to infection and long…
- Trial name
- NCT00356187
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Denver Health and Hospital Authority
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Earthquake, Crush Injury
Our Anesthesia Experiment Applied to Child Earthquake Victims in the February 6, 2023 Earthquake
The study aimed to investigate anesthesia management of pediatric patients in the Ankara Bilkent City Hospital during the earthquake disaster of February 6.
- Conditions
- Earthquake, Crush Injury, Anesthesia
- Trial name
- NCT06310265
- Testing
- Retrospective observational study
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Carpal Tunnel Syndrome
Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release
Hand surgeons have many options to perform carpal tunnel release surgery. Some surgeons believe that techniques are best kept simple: a mini-open incision that allows adequate exposure of the transverse carpal ligament (TCL)…
- Trial name
- NCT05325567
- Testing
- Mini open incision CTR
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Methanol Poisoning, Toxic Optic Neuropathy
Therapy of Toxic Optic Neuropathy Via Combination of Stem Cells With Electromagnetic Stimulation
The axons of the retinal ganglion cells combine to form the optic nerve. The optic nerve transmits electrical signals to the visual cortex by various synapses.
- Conditions
- Methanol Poisoning, Toxic Optic Neuropathy, Stem Cell Tyrosine Kinase 1 Y842X, Magnetic Field Exposure
- Trial name
- Magnovision (NCT04877067)
- Testing
- Wharton jelly derived mesenchymal stem cell, Repetitive electromagnetic stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Ankara Universitesi Teknokent
Inguinal Hernia, Transversus Abdominis Plane (TAP) Block
Comparison of Postoperative Analgesic Efficacy of Ultrasound-Guided Ilioinguinal-Iliohypogastric Block, Transversus Abdominis Plane Block, and Quadratus Lumborum Block in Inguinal Hernia Surgery
Inguinal hernia is a common condition, particularly among male patients, and represents one of the most frequent indications for lower abdominal surgeries.
- Conditions
- Inguinal Hernia, Transversus Abdominis Plane (TAP) Block, Iliohypogastric/Ilioinguinal Nerve Block, Quadratus Lumborum Block
- Trial name
- NCT06997536
- Testing
- Ilioinguinal/iliohypogastric Nerve Block, Transversus abdominis plane (TAP) block, Quadratus Lumborum Block (QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Namik Kemal University
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