Clinical trials: WOUNDS INJURIES
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Split-thickness Skin Graft Donor Sites, Burns
Molecular, Histologic, and Clinical Analysis of Negative Pressure Wound Therapy (NPWT) for Split-thickness Skin Graft (STSG) Donor Sites
The purpose of this single-center, randomized, prospective cohort study is to evaluate the clinical outcome and negative-pressure wound therapy (NPWT) mediated modulation of the biologic milieu of a modified NPWT dressing on…
- Trial name
- NCT02712164
- Testing
- Modified NPWT dressing, Tegaderm
- Sponsor
- Brigham and Women's Hospital
Hip Fractures
Care Pathway for Sub-acute Hip Rehabilitation
The effectiveness of integrated care pathways for hip fractures in sub-acute rehabilitation settings is not known. The study objective was to assess if a hip fracture integrated care pathway at a sub-acute rehabilitation facility…
- Trial name
- NCT03906864
- Testing
- Care Pathway
- Where
- Singapore
- Volunteers
- 162 people
- Sponsor
- St Luke's Hospital, Singapore
Brain Injuries
Tranexamic Acid for Preventing Progressive Intracranial Haemorrhage in Traumatic Brain Injury
The study's objective is to evaluate the effectiveness and safety of tranexamic acid for adult patients with moderate to severe TBI.With the research question as "Does TXA reduce the incidence of progressive intracranial…
- Trial name
- NCT00755209
- Testing
- tranexamic acid
- Where
- Thailand
- Volunteers
- 238 people
- Sponsor
- Khon Kaen University
Wound
Wound Catheter Vs LA Bolus in Renal Transplant: RCT
Pain control is an important part of patients' care after a kidney transplant. Currently patients receive a one off injection of Local Anaesthetic (LA) in the wound at the end of the operation followed by Intravenous morphine…
- Trial name
- NCT06011421
- Testing
- Local Anaesthetic Wound Catheter Insertion
- Where
- 2 sites in United Kingdom
- Volunteers
- 88 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Hip Fractures
Comparison of Biochemical Changes in Patients With Trochanteric Region Fracture Fixation With DHS Versus PFN
Hip fractures are one of the most frequent fractures in older adults. There is still controversy which surgical strategy is the best option for treatment of hip fractures especially trochanteric region fractures.
- Trial name
- NCT03849014
- Testing
- Dynamic Hip Screw, Proximal Femoral Nail
- Where
- Kosovo
- Volunteers
- 60 people
- Sponsor
- Kushtrim Grezda
SCI - Spinal Cord Injury
Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study
This study is an open label extension of the SCI EFS clinical trial (NCT04288245) that developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury.
- Trial name
- SCI-AFOS (NCT06351111)
- Testing
- Active VNS
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas at Dallas
Athletic Injuries, Sprains and Strains
The Design and Evaluation of an Active Intervention for the Prevention of Non-contact ACL Injury
The overall goal of this project is to reduce the risk for anterior cruciate ligament injuries by designing a targeted intervention that will alter the known kinematic and kinetic risk factors associated with ACL injuries.
- Conditions
- Athletic Injuries, Sprains and Strains, Wounds and Injuries, Knee Injuries
- Trial name
- NCT01021111
- Testing
- Activity Training with Feedback
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Stanford University
Trauma, Rehabilitation
NMES and Pelvic Fracture Rehabilitation
Objectives: The acute care of pelvic fractures has improved recently however there are no formal guidelines for rehabilitation of these types of fractures. Patients have long periods of non-weight bearing causing muscle wastage.
- Trial name
- NCT03278834
- Testing
- Neuromuscular muscle stimulation machine- Strength Setting, Neuromuscular muscle stimulation machine - TENS Setting
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Shoulder Injuries
Kinesiophobia Scale for the Upper Extremity
Questionnaires/scales used to evaluate kinesiophobia in the literature are limited and are not specific to the upper extremity in existing scales.
- Trial name
- NCT06485934
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Emre Şenocak
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Trauma, Acute Hemorrhage
Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage
The prognosis of traumatized hemorrhages is correlated with the nature of transfusion therapy: a 50% reduction in mortality for an early and massive supply of plasma, and 20% for an early and massive supply of platelets.
- Conditions
- Trauma, Acute Hemorrhage, Coagulopathy
- Trial name
- T-STORHM (NCT04431999)
- Testing
- Whole blood transfusion, Fractionated blood products transfusion
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Primary Brain Tumour, Radiation Toxicity
Cognitive Function After Radiation Therapy for Primary Brain Tumours
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction.
- Conditions
- Primary Brain Tumour, Radiation Toxicity, Cognitive Impairment
- Trial name
- NCT04306432
- Testing
- Cognitive tests and Patient Reported Outcomes
- Where
- 5 sites in Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Humeral Fractures, Proximal
Treatment of Proximal Humeral Fractures
This trial is designed to compare head-to-head conservative with operative treatment in 2 stratum. Stratum 1: In 2 part fractures the comparison is between conservative treatment and operative treatment with plate fixation with…
- Trial name
- TPHF (NCT01246167)
- Testing
- Philos, Epoca, Control group
- Where
- 6 sites in Denmark, Estonia and 2 more
- Volunteers
- 250 people
- Sponsor
- Tampere University Hospital
Concussion, Mild, Concussion; Eye
EYE-SYNC Concussion Classification Study
The purpose of this study is to determine the sensitivity and specificity of an aid in assessment of concussion based on eye-tracking, in comparison to a clinical reference standard appropriate for sport-related concussion…
- Conditions
- Concussion, Mild, Concussion; Eye, Concussion, Brain, Concussion, Severe
- Trial name
- NCT04381767
- Testing
- EYE-SYNC
- Where
- United States
- Volunteers
- 1,303 people
- Sponsor
- Sync-Think, Inc.
Whiplash Injuries
Shifting Away From Pain: Neurocognitive Approach to Explain and Predict Recovery Following Whiplash Injury
Around half of the patients with neck pain after trauma (whiplash) will develop chronic pain. Understanding the transition from acute to chronic pain after whiplash is a priority since will help to identify those which patients…
- Trial name
- NCT05161767
- Testing
- Brain MRI (neuroimaging)
- Where
- Belgium
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Ghent
Traumatic Brain Injury
Impact of v Release on Dysphagia in Patients With Traumatic Brain Injury
The goal of this clinical trial is to explore Clinical Effect of Myofascial Release Therapy in Dysphagic Traumatic Brain injured Survivors.
- Trial name
- NCT06328309
- Testing
- Rehabilitation treatment, Myofascial Release Therapy
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Brain Injury
Genotype Influence on Recovery After Traumatic Brain Injury
Genetic differences in response to brain injury may reasonably be expected to play a role in the initial consequences of traumatic brain injury and in the rate of recovery from such injury.
- Trial name
- NCT00018499
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Brachial Plexus Palsy Due to Birth Trauma, Injury
Non-Anesthetized Plexus Technique for Infant (BPBP) MRI Evaluation
The investigators are studying the ability of a novel rapid magnetic resonance imaging (MRI) protocol to provide more accurate and earlier information about whether an infant with brachial plexus birth palsy will require nerve…
- Conditions
- Brachial Plexus Palsy Due to Birth Trauma, Injury, Newborn
- Trial name
- NAPTIME (NCT03560999)
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Shriners Hospitals for Children
Femoral Neck Fractures
Drug Related Problems Among Patients With Femoral Neck Fractures in an Orthopedic Ward
the purpose of the study is to: 1. Identify and characterize drug related problems in patients after a femur neck fracture that are hospitalized in the orthopedic department at "Meir" medical center. 2.
- Trial name
- NCT01844544
- Testing
- inspection of medical records
- Where
- Israel
- Volunteers
- 104 people
- Sponsor
- Meir Medical Center
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