Clinical trials: WOUNDS INJURIES
Distal Radius Fractures
Do Generic Volar Locking Plates Provide Similar Outcomes at a Reduced Cost?
Across orthopedics, the investigators will be using the generic volar locking plates for patients undergoing open reduction and internal fixation (ORIF) of the distal radius using a block schedule, meaning one month we the…
- Trial name
- NCT06343467
- Testing
- Generic Volar Locking Plate, Conventional Volar Locking Plate
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
PRESSURE INJURIES
Pressure Injuries in the Operating Room and Their Perioperative Incidence in Patients Undergoing Neurosurgery.
This research project is a descriptive, longitudinal prospective observational study in the HUMV neurosurgery operating rooms. The patients included will be adults 18 years old or older, who will be scheduled for surgery by the…
- Trial name
- UPS (NCT06615271)
- Testing
- Neurosurgery
- Where
- 2 sites in Spain
- Volunteers
- 170 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Brain Injuries
Acceptance and Commitment Therapy (ACT) and Carers
Background: Research has extensively documented the adverse impact that caring for an individual with an acquired brain injury can have including financial difficulties, social isolation, family tension and conflict, relationship…
- Trial name
- NCT02584101
- Testing
- ACT, Enhanced Treatment as Usual
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Distal Radius Fracture
Above-versus Below-elbow Casting for Conservative Treatment of Distal Radius Fractures
For the non-surgical treatment of distal radius fractures in adults a variety cast options are available, including or not the elbow joint.
- Trial name
- NCT03126175
- Testing
- Below elbow immobilization, Above elbow immobilization
- Where
- Brazil
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Dr. Fernando Mauro Pires da Rocha
Ureteropelvic Junction Obstruction, Ureteropelvic Junction; Obstruction, Congenital
Decision Aid for Parents of Infants With UPJO
Ureteropelvic junction obstruction (UPJO) is the most common etiology of high-grade hydronephrosis, affecting approximately 4,000-10,000 infants annually in the U.S.
- Trial name
- NCT05900375
- Testing
- Parent Decision Aid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Traumatic Brain Injury, Diffuse Axonal Injury
Brain Stimulation for Traumatic Brain Injury
The purpose of this study is to determine whether repetitive Transcranial Magnetic Stimulation (rTMS) is effective in the cognitive rehabilitation of patients with diffuse axonal injury(DAI) after Traumatic Brain Injury(TBI).
- Trial name
- TMS/DAI (NCT02167971)
- Testing
- Active Coil
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Lung Injury
Functional Residual Capacity and Alveolar Recruitment in Single-lung Ventilation: a Randomized Study
In thoracic surgery, the incidence of postoperative pulmonary complications is higher than for other surgeries. Indeed, thoracic surgery has the specificity of being carried out with single-lung ventilation and is thus a source…
- Trial name
- OLVEELV (NCT06446544)
- Testing
- VPFE monitoring with intraoperative alveolar recruitment maneuvers.
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Rouen
Spinal Cord Injury, Hypogonadism
Testosterone Replacement Therapy in Chronic Spinal Cord Injury
It has long been recognized that co-morbidity associated with multiple metabolic syndrome, such as adverse body composition, insulin resistance and autonomic nervous system impairment, may lead to significant increase in…
- Trial name
- NCT00266864
- Testing
- Testosterone Transdermal System (Androderm 5 mg patch)
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- VA Office of Research and Development
Cisplatin Adverse Reaction, Hearing Loss Ototoxic
Protective Role of N-acetylcisteine From Cisplatin-induced Ototoxicity in Patients With Head and Neck Cancer
Introduction. Cisplatin-induced ototoxicity is a very frequent event and its consequences can cause a lot of deterioration in patients.
- Trial name
- NCT03400709
- Testing
- N Acetylcysteine
- Where
- Chile
- Volunteers
- 45 people
- Sponsor
- Hospital San Juan de Dios, Santiago
Fracture Nonunion, Infection
Smoking Cessation in Nonunion, Malunion, Osseous Infection
The Study Investigators have seen high rates of tobacco cessation success combining Chantix with the risk of no surgery, should tobacco use continue.
- Trial name
- nicotine (NCT00754299)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Burns
Novel Virtual Reality for Burn Wound Care Pain in Adolescents
Burn wounds cause intense, complex pain, and subsequent burn wound care causes further intense, episodic pain that is often unrelieved by opioid and non-opioid medications, resulting in under-treatment of pain.
- Trial name
- NCT03155607
- Testing
- Virtual Reality Distraction
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Arkansas
Spinal Cord Injuries, Dietary Habits
Assessing Dietary Requirements in Relation to Resting Metabolic Rate in Spinal Cord Injury
Assess the relationship between body composition, metabolism, and dietary needs in people with spinal cord injury compared to their healthy controls that are age and sex matched.
- Trial name
- NCT03518892
- Testing
- Resting Metabolic Rate, Body Composition, Dietary Assessment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Eyelid; Wound
Evaluation of Patient Satisfaction With Blephaderm as a Complementary Care in Post-eyelid Surgery
The goal of this non-interventional, open and monocentric study is to evaluate the satisfaction of 30 patients, after 3 months with Blephaderm eyelid cream, as a complementary care in post-eyelid surgery (Blepharopasty or…
- Trial name
- NCT07234292
- Testing
- Cosmetic: Blephaderm
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Laboratoires Thea
Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome
Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
This project aims to investigate whether an increase in step rate can be used to reduce pain and injury causing movement patterns in runners who are currently experiencing achilles tendonopathy, iliotibial band syndrome…
- Conditions
- Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome, Iliotibial Band Syndrome, Achilles Tendinopathy
- Trial name
- NCT03067545
- Testing
- Step rate increase
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Salford
Wounds and Injuries, Physical Activity
Swiss Army Physical Fitness Training
The purpose of this study is to determine whether the new sport concept of the Swiss Armed Forces influences the physical and psychological fitness of the recruits.
- Conditions
- Wounds and Injuries, Physical Activity, Mood (Psychological Function), Motivation
- Trial name
- SAFT (NCT02570295)
- Testing
- Swiss Army Physical Fitness Training
- Where
- Switzerland
- Volunteers
- 722 people
- Sponsor
- Swiss Federal Institute of Sport Magglingen
Fractures, Closed
Lateral Versus Anterior Spanning External Fixator for Tibial Plateau Fractures
The purpose of this study is to evaluate patients with tibial plateau fractures.
- Trial name
- NCT00610701
- Testing
- Anterior pin placement, Lateral pin placement
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Missouri-Columbia
Head Trauma, Cognitive Manifestations
Prevention of Head Impacts in Football: The HuTT Technique
The purpose of the study is to determine the effectiveness of the helmet-less tackling training (the HuTT Technique) intervention to reduce head impacts in high school football players and to gain an understanding of the…
- Trial name
- HuTT (NCT02519478)
- Testing
- Helmetless Tackling Training (HuTT)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Substance Use Disorders, PTSD
A Mobile App for Peer-led Seeking Safety
Peer support is historically prominent for substance use disorder (SUD), such as the world-wide model of Alcoholics Anonymous and other 12-step groups.
- Conditions
- Substance Use Disorders, PTSD, Trauma, Emotional Dysfunction
- Trial name
- NCT03846115
- Testing
- Peer-Led Seeking Safety app, Control app
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Treatment Innovations
Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion
Laminectomy with internal fixation and osseofusion is a common surgery for treating degenerative spinal diseases. It removes excessive bone spurs and removes the lamina for decompression to relieve nerve compression, and then…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Spinal Stenosis, Scoliosis
- Trial name
- NCT06532968
- Testing
- ORION spinal lamina cover
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Orion Biotech Inc.
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