Clinical trials: WOUNDS INJURIES
Pain, Shoulder Injury
Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention
Nerve blocks, or pain medication injected next to the nerve while patients are asleep, are commonly used for pain management after shoulder surgery and are considered highly effective in decreasing post-operative pain.
- Trial name
- NCT02666118
- Testing
- Preemptive Interscalene Block - Single Shot, Postoperative Interscalene Block- Single Shot, Preemptive Interscalene Block - Catheter
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Severe Trauma Patients, Acute Kidney Injury
Plasmalyte Versus Saline in Trauma Patients
Fluid resuscitation remains the cornerstone for the care of severe trauma patients to compensate for blood loss, to compensate for capillary leak induced by systemic inflammation but also to prevent the detrimental consequences…
- Trial name
- ASTRAU (NCT03630224)
- Testing
- Plasmalyte Viaflo, NaCl 0.9%
- Where
- France
- Volunteers
- 365 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries
Validity and Reliability of the 2-minute Walk Test in Individuals With a Spinal Cord Injury
There exist a variety of outcome measures to asses gait function in individuals with a spinal cord injury (SCI). The most established measures are the 10-meter walk test (10MWT) and the 6-minute walk test (6mWT).
- Trial name
- NCT04555759
- Testing
- 2-minute walk test
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Chronic SDH and the Efficacy of Embolization
Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
This study is designed to evaluate the effectiveness of endovascular embolization of middle meningeal artery following evacuation of subdural hematomas (SDHs) to assess rate of recurrence.
- Trial name
- endovascular (NCT04272996)
- Testing
- Craniotomy only, Craniotomy + Endovascular embolization of the middle meningeal vessels
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Sport-related Concussion
Sub-acute Exercise Following Sport-Related Concussion
Determine the safety and efficacy of sub-maximal aerobic exercise during the subacute phase of recovery following sport-related concussion.
- Trial name
- NCT03575455
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Tennis Elbow
Comparison of Mulligan Technique and Muscle Energy Technique in Lateral Epicondylitis
In this study, the effects of mulligan and muscle energy techniques on pain, grip strength and functionality will be investigated in a randomized controlled manner in individuals with lateral epicondylitis.
- Trial name
- NCT04505215
- Testing
- Mulligan Technique, Muscle Energy Technique, Only Exercise (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- KTO Karatay University
Ankle Fractures, Ankle Injuries
Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Validation Study
Ankle fractures are common injuries that can affect a patient's mobility, mood, sleep, and everyday life for months. The Ankle Fracture Outcome of Rehabilitation Measure (A-FORM) is an English-language patient-reported outcome…
- Trial name
- A-FORM-TR (NCT07620015)
- Where
- 3 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Utku Gürhan
Stomach Cancer
The Effect of Deep Neuromuscular Block on the Perioperative Stress Response Reduction and Postoperative Recovery Enhancement in Robot-assisted Stomach Cancer Surgery
Stress reactions caused by surgical stimuli can cause sympathetic nervous system activation and increased stress hormones, such as catecholamines, inflammatory cytokines, and pituitary hormones, and insulin resistance.
- Trial name
- NCT03937440
- Testing
- Deep neuromuscular block with 'rocunium®', Moderate neuromuscular block with 'rocunium®'
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yonsei University
Shoulder Impingement Syndrome
Electromyographic Activity of Posterior Oblique Sling Muscles in Patients With Shoulder Impingement Syndrome
this study aims to assess the gluteus maximus muscle electromyographic activity and the latissimus dorsi muscle electromyographic activity in patients with shoulder impingement syndrome , to improve the assessment procedure and…
- Trial name
- EMG (NCT06789991)
- Testing
- electromyography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infections, Infected Wound
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
This is a Phase III clinical randomized control trial to investigate differences between patient with an infected nonunion treated by PO vs. IV antibiotics.
- Conditions
- Infections, Infected Wound, Nonunion of Fracture, Injury Leg
- Trial name
- POvIV2 (NCT05699174)
- Testing
- Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
- Where
- 13 sites in United States
- Volunteers
- 250 people
- Sponsor
- Major Extremity Trauma Research Consortium
Spinal Cord Injuries, Gait Disorders, Neurologic
Safety and Feasibility of TWIICE Rise
The aim of this study is to assess the safety and the feasibility of two versions of TWIICE Rise for exoskeleton-assisted ambulation in patients with a spinal cord injury.
- Trial name
- NCT05926310
- Testing
- TWIICE Rise
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- TWIICE
Hand Injury
Retroclavicular Versus Supraclavicular Brachial Plexus Block for Hand and Forearm Surgery
Patients will be randomized to one of two groups: 1. Supraclavicular group: supraclavicular brachial plexus block performed with the aid of ultrasound; 2.
- Trial name
- NCT02641613
- Testing
- retroclavicular block, supraclavicular block
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Hôpital du Valais
Spinal Cord Injury
Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI)
The primary goal of the proposed clinical trial is to investigate the combined effects of walking training and monoaminergic agents (SSRIs and TIZ) on motor function of individuals in sub-acute (2-7 mo) human motor incomplete…
- Trial name
- NCT01753882
- Testing
- Lexapro
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Shirley Ryan AbilityLab
Rotator Cuff Tear
Rotator Cuff Injury to Surgery
The purpose of this prospective randomized controlled trial is to compare post-operative outcome between participants undergoing expedited surgery compared to those proceeding through a 'typical' wait time process.
- Trial name
- RC-IS (NCT01744080)
- Testing
- Regular Wait Time, Early Surgery
- Where
- Canada
- Sponsor
- Panam Clinic
Lung Injury, Pulmonary Complication
Intraoperative Mechanical Power and Ventilation-Associated Lung Injury: Assessing Complications
This study investigates the relationship between intraoperative mechanical power and postoperative pulmonary complications in patients undergoing major abdominal surgery.
- Trial name
- NCT06375980
- Testing
- Intraoperative Mechanical Ventilation Strategies
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Fracture of Tibia Proximal Plateau
Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation
Postoperative rehabilitation for tibial plateau fracture generally involves prolonged non-weight bearing time while other protocols use partial weight-bearing and bracing before full weight-bearing is recommended at 9 to 12 weeks…
- Trial name
- NCT05502679
- Testing
- Weight bearing as tolerated, Pragmatic Exercise protocol
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Mechanical Ventilation Complication, Brain Injuries
Mechanical Ventilation on Hippocampus
Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain.
- Trial name
- NCT06480162
- Testing
- Mechanical ventilation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Sanbo Brain Hospital
Diabetic Foot Ulcer, Wound
Investigation of the Effects of Different Exercise on Wound Healing in Patients wıth Diabetic Foot Wounds
Diabetic foot ulcers are a common complication of diabetes mellitus and are associated with delayed wound healing, impaired quality of life, and an increased risk of lower extremity amputation.
- Trial name
- NCT05422846
- Testing
- standard treatment, aerobic exercise, exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Harran University
Osteoporosis, Osteoporosis Fracture
The Effect of Semaglutide on Bone Health
Semaglutide has effects that include lowering blood sugar, reducing weight, and improving cardiovascular and renal outcomes, and it is now widely used in clinical practice.
- Conditions
- Osteoporosis, Osteoporosis Fracture, T2DM
- Trial name
- NCT07165158
- Testing
- semaglutide combined with metformin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
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