Clinical trials: WOUNDS INJURIES
Venous Leg Ulcer, Pressure Ulcer
Confirm Safety and Performance of Avance Solo and Avance Solo Adapt NPWT Systems
The primary objective of this post market clinical follow-up (PMCF) investigation is to confirm the safety and performance of Avance®Solo and Avance®Solo Adapt NPWT Systems in low to moderate exuding chronic wounds when used in…
- Conditions
- Venous Leg Ulcer, Pressure Ulcer, Diabetic Foot Ulcer, Chronic Ulcer
- Trial name
- ASOLO-CW (NCT04753294)
- Testing
- Avance Solo NPWT System, Avance Solo Adapt NPWT System
- Where
- 13 sites in Belgium, Denmark and 5 more
- Volunteers
- 136 people
- Sponsor
- Molnlycke Health Care AB
Pituitary Tumor, Cerebrospinal Fluid Leakage
Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage
The papers propose a new method to prevent postoperative cerebrospinal fluid leakage. Doctors use the absorbable polyglycolic acid (PGA) and fibrin glue to repair in surgery, prevent cerebrospinal fluid leakage and reduce the…
- Trial name
- NCT06472505
- Testing
- polyglycolic acid(Neoveil)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Degenerative Disc Disease (DDD), Instabilities
PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.
In accordance with the European Medical Device Regulation MDR 2017/745/EU, the legal manufacturers of medical devices are obliged to evaluate medical devices with regard to their clinical performance and safety.
- Conditions
- Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
- Trial name
- NCT05489822
- Testing
- VERTICALE® Cervical System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Silony Medical GmbH
Craniocerebral Trauma
Pilot Study of the Use of a Portable Cranial Scanner in Intensive Care for Cerebro-injured Patients
Cerebral scans are a key examination in the management of serious brain-injured patients in intensive care, and are often repeated in the initial phase.
- Trial name
- ESPER (NCT05891522)
- Testing
- portable scanner, fixed scanner
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Rennes University Hospital
Hip Injuries
THA Kinematics and Sound for Subjects for Normal, Diseased and Implanted Hips
The objective of this study is to analyze subjects having a normal hip and compare the in vivo kinematics to subjects requiring a total hip arthroplasty (THA) due to having a diseased hip and then later post-operative to their…
- Trial name
- NCT02682602
- Testing
- DePuy Synthes total hip arthroplasty, Computer tomography, Fluoroscopy surveillance
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- The University of Tennessee, Knoxville
Cleft Palate, Trauma
Cell Therapy for Craniofacial Bone Defects
The purpose of this research is to determine if a patient's own bone marrow tissue can help regenerate bone in the area of the jaw where an implant will be placed. The name of the process is called Bone Repair Cell (BRC) Therapy.
- Trial name
- NCT01616953
- Testing
- Ixmyelocel-T, Autogenous Bone Grafting
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Brain Concussion, Brain Injuries
Screening Brain MRI in High School Football: Does the Guardian Cap Reduce the Risk of Traumatic Brain Injury
Screening Brain magnetic resonance imaging (MRI) with Fluid-attenuated Inversion Recovery (FLAIR) and Susceptibility Weighted Imaging (SWI) sequences will be performed pre and post season on high school football players.
- Conditions
- Brain Concussion, Brain Injuries, Diffuse Axonal Injury, Athletic Injuries
- Trial name
- NCT02757053
- Testing
- Guardian Cap
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mosaic Life Care
Sports-related Concussion
The Impact of Riboflavin on Sports-related Concussion
The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.
- Trial name
- NCT02772237
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Carpal Tunnel Syndrome (CTS)
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the effectiveness of rest splints and high-intensity laser therapy(HILT) added to physical therapy programs for patients with carpal tunnel syndrome in terms of pain, function, nerve conduction…
- Trial name
- NCT07294157
- Testing
- Rest splint group, high-intensity laser therapy (HILT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Afyonkarahisar Health Sciences University
SCI - Spinal Cord Injury
The Efficacy of Upper Extremity Wearable Robotic Orthosis on Improving Upper Extremity Motor Function and Activities of Daily Living in Persons With Spinal Cord Injury
To evaluate the usefulness of an upper extremity (UE) assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury (iSCI)
- Trial name
- MyoMo in SCI (NCT04855812)
- Testing
- MyoMo, Myo-SB, Control
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Kessler Foundation
Heat Stress, Heat Strain
Effects of Solar Radiation on Human Function and Cognition
Solar radiation is a physical phenomenon which interacts with any human being throughout its life on earth. This interaction is associated with numerous physiological functions, as well as a broad spectrum of deleterious effects…
- Trial name
- NCT04160741
- Testing
- Radiation and warm environment, Warm environment, Neutral environment with radiation
- Where
- Greece
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Brain Injury, Muscle Weakness
A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial
Intensive care unit (ICU) hospitalization saves lives but often does so at a high personal cost to ICU survivors who frequently experience significant cognitive impairment and an array of physical and functional disabilities that…
- Trial name
- RETURN (NCT00715494)
- Testing
- Cognitive, physical, and functional rehabilitation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Pilonidal Sinus
A Preliminary, Non-comparative Study to Evaluate a Bioresorbable Wound Scaffold in Acute Wounds
As this is a proof-of-concept study, the primary objective is to provide preliminary data on the safety and efficacy of Bioresorbable Wound Scaffold in the management of acute wounds left to heal by secondary intent.
- Trial name
- NCT01081522
- Where
- 3 sites in Denmark, United Kingdom
- Volunteers
- 12 people
- Sponsor
- ConvaTec Inc.
Lung Injury
Effect of Variable Volume Ventilation on Lung Compliance
Randomized controlled trial comparing low inspiratory and expiratory flow during variable volume ventilation with a constant volume decelerating flow (pressure controlled volume guarantee) ventilation.
- Trial name
- NCT03661502
- Testing
- VVV, PCV
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- AZ Sint-Jan AV
Low Back Pain, Postural; Strain
Mézières Therapy in the UCAM's Athletes With Low Back Pain
The purpose of this research study focuses on the re-harmonization of the kinetic chains and posture based on spinal muscular atrophy and global stretching while trying to test the effectiveness of Mézières therapy on sports…
- Trial name
- NCT03849053
- Testing
- Mézières Therapy for Low back pain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Spinal Cord Injuries
Exercise for People with Spinal Cord Injury
The purpose of the study is to examine the impact of a transitional exercise intervention implemented in the community for people with SCI on psychological well-being, social factors, and physiological health.
- Trial name
- NCT04007445
- Testing
- Formally Directed Group (Exercise Group), Self-Directed Group (Control Group)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Washington University School of Medicine
Non-small Cell Lung Cancer, Radiation Toxicity
Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy
Lung cancer is the most common cause of cancer death in Canada. For approximately 30% of patients that present with locally-advanced non-small cell lung cancer (NSCLC), the standard treatment is curative-intent concurrent…
- Trial name
- RICT-LUNG (NCT03416972)
- Testing
- Standard platinum-based chemoradiotherapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Thermoregulation, Cold Exposure
Effect of Pre-cooling on Whole-body Heat Loss During Exercise-heat Stress
Endurance exercise performance declines in hot environments as core body temperature increases. To enhance performance, body pre-cooling strategies, such as cold-water immersion have been employed to lower resting core…
- Conditions
- Thermoregulation, Cold Exposure, Heat Stress, Exercise
- Trial name
- NCT06670339
- Testing
- No Cooling, Pre-Cooling
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Wound Infection
Swabbing of Subcutaneous Tissues of Cesarean Section Wounds With Povidone Iodine
The study has 2 groups. Group A in which the subcutaneous tissue will be swabbed with 10 cc of undiluted 10% povidone iodine and will not be mobbed. Group B ; No swabbing.
- Trial name
- NCT02868372
- Testing
- Povidone iodine
- Volunteers
- 538 people
- Sponsor
- Assiut University
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