Clinical trials: WOUNDS INJURIES
Rib Fractures, Pain
Analgesic Effect of Intranasal Calcitonin on Patients With Fractured Ribs
This study, which will be conducted at the emergency room of the Sacré-Cœur hospital, requires the recruitment of 60 subjects and involves some telephone follow-up.
- Trial name
- NCT00444808
- Testing
- Intranasal calcitonin
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Université de Montréal
Shoulder Fractures
Parathyroid Hormone for the Treatment of Humerus Fractures
Hypothesis: The investigators want to study whether parathyroid hormone improves healing of humerus after a fracture. The investigators will assess healing of the humerus with Constant score.
- Trial name
- NCT01687374
- Testing
- 1-84 parathyroid hormone
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Hvidovre University Hospital
Brain Injuries, Traumatic
The Role of MEG in Assessment and Diagnosis In mTBI
Head injuries are responsible for 1.4 million visits to hospital each year in the United Kingdom (UK). Most patients are allowed home the same day and make a full recovery, but some will have persistent symptoms.
- Trial name
- MEGAbIT (NCT03867513)
- Testing
- Multimodal imaging
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Nottingham
Tranexamic Acid, Trauma
Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery
This study was done to evaluate the efficacy of Tranexamic Acid (TXA) in reducing blood transfusion requirement in patients of lower limb trauma undergoing surgery.
- Conditions
- Tranexamic Acid, Trauma, Lower Extremity Fracture
- Trial name
- NCT04986813
- Testing
- Tranexamic acid injection, Normal Saline
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Jaspreet Singh
Traumatic Brain Injury
Optimized Sleep After Brain Injury: Sleep Hygiene Intervention After Traumatic Brain Injury
OSABI is a pilot study of a sleep hygiene protocol for sleep disruptions associated with TBI during inpatient rehabilitation. Twenty participants will be allocated (by minimization) either into a standard of care protocol or a…
- Trial name
- OSABI (NCT02838082)
- Testing
- Sleep Hygiene Protocol, Standard of Care
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Craig Hospital
Wounds and Injuries
Feasibility Study for Fibroblast Autologous Skin Grafts
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
- Trial name
- NCT01964859
- Testing
- autologous skin fibroblasts, Filler Product
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain, Postoperative, Bariatric Surgery Candidate
A Study to Compare Two Techniques for Pain Control After Bariatric Surgery
The purpose of this study is to compare the postoperative pain and other clinical outcomes in patients who, during bariatric surgery, will be injected with a local anesthetic (Ropivacaine) through two different techniques.
- Trial name
- NCT04427059
- Testing
- Transversus Abdominis Plane (TAP) block, Port-Site Infiltration (PSI)
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- Fabio Garofalo
Wounds and Injuries, Respiratory Failure
FiO2 Closed Loop Control Ventilation
A randomized, multi-center trial involving critically-ill patients comparing conventional, manual control of inspired oxygen (FiO2) within a target range, with a computer-controlled, closed-loop FiO2 delivery using a continuous…
- Trial name
- CLC (NCT02810080)
- Testing
- Closed Loop Control Ventilation, Manual Control Ventilation
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Zoll Medical Corporation
Bone Loss
Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
This is a double-blind, randomized, placebo-controlled trial of zoledronic acid, 5mg, to be administered intravenously to people who have suffered an acute spinal cord fracture.
- Trial name
- NCT00844480
- Testing
- zoledronic acid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Thomas J. Schnitzer
Spinal Cord Injury
Resolving Grief After Spinal Cord Injury
The purpose of this study is to examine the usefulness of the Grief Recovery Method in assisting persons with spinal cord injuries to achieve as complete a recovery as possible, thereby allowing for fuller participation in life.
- Trial name
- NCT01957358
- Testing
- The Grief Recovery Method
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Dr. Karen Ethans
Anterior Cruciate Ligament Rupture
Are Clinical Outcomes Unchanged by ALL Fixation at 0° or 30° of Knee Flexion in Combined ACL-ALL Reconstruction? Despite Numerous Technical Descriptions of Anterolateral Procedures, There is Limited Knowledge Regarding the Effect of Knee Flexion Angle During Graft Fixation.
This study evaluates whether the knee flexion angle used during fixation of the anterolateral ligament (ALL) affects clinical outcomes in patients undergoing combined anterior cruciate ligament (ACL) and ALL reconstruction.
- Trial name
- ACL ALL (NCT07451743)
- Testing
- anterolateral ligament reconstruction
- Volunteers
- 100 people
- Sponsor
- ASL Lecce
Oral Mucositis Due to Radiation
A Sequential Cohort Study Exploring GELCLAIR in the Management of Oral Mucositis in Patients Receiving Radical Radiation for Head and Neck Cancer
The goal of this clinical trial is to learn if Gelclair lubricant gel can help manage Oral Mucositis (OM) among Oropharyngeal and Oral cavity cancer patients receiving radiation treatment.
- Trial name
- GOMS (NCT06897215)
- Testing
- Hyaluronic acid hydrogel
- Volunteers
- 48 people
- Sponsor
- Nova Scotia Health Authority
Spinal Cord Injuries, Spine Disease
Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)
This randomized clinical trial will compare three groups of individuals with cervical/thoracic, complete or incomplete spinal cord injury (SCI) that will undergo: (i) early CPAP therapy in the management of moderate-to-severe…
- Trial name
- NCT05473689
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Hip Arthroplasty Replacement, Femoral Fractures
Cephalic Femoral Heads Follow Up
Study design: monocentric, retrospective, observational and post-market clinical study. Purpose: To demonstrate the safety and performance of cephalic femoral heads.
- Trial name
- NCT06873568
- Where
- Slovakia
- Volunteers
- 47 people
- Sponsor
- Limacorporate S.p.a
Burn, Skin Graft
The Effects of Therapeutic Resources on Structure and Function of Normal and Burned Skin
Burning produces changes in the biomechanical properties of the skin causing limitation of movement. The increase in skin suppleness is very important in the rehabilitation process, since its increase makes therapeutic…
- Trial name
- NCT02185950
- Testing
- ultrasound, paraffin, endermotherapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Traumatic Brain Injury
Cold-stored Platelet Early Intervention in TBI
The Cold Stored Platelet Early Intervention in Traumatic Brain Injury (CriSP-TBI) trial is a proposed 3 year, open label, single center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent…
- Trial name
- CriSP-TBI (NCT04726410)
- Testing
- Cold Stored Platelets, Standard Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jason Sperry
Penetrating Injury, COVID-19
Social Determinants of Health in Patients With Penetrating Trauma Injuries Before and During the COVID-19 Pandemic
Investigators report on the impact of the COVID-19 stay-at-home order concerning penetrating violence and its association within different socioeconomic regions within the county.
- Conditions
- Penetrating Injury, COVID-19, Social Determinants of Health
- Trial name
- NCT06135610
- Testing
- Postive SAR-CoV-2 PCR nasopharyngeal swab
- Where
- United States
- Volunteers
- 803 people
- Sponsor
- Kern Medical Center
Fractures, Bone, Upper Extremity Injury
Ultrasonography in Fracture Management
The bone fracture is usually diagnosed using an X-ray examination (the method of choice). However, in the case of the youngest patients (children and adolescents), it carries a potential risk of X-ray radiation exposure.
- Conditions
- Fractures, Bone, Upper Extremity Injury, Healing Fracture of Bone, Vascularization
- Trial name
- UFrac (NCT04501510)
- Testing
- Ultrasonographic examination validation and testing
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury
Acquired Brain Injury, Coma
Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot Study
This is a pilot study. The objective is to further understand the mechanism by which amantadine improves function in patients with persistent vegetative state and minimally conscious state.
- Conditions
- Acquired Brain Injury, Coma, Persistent Vegetative State, Minimally Conscious State
- Trial name
- NCT02566720
- Testing
- Amantadine, MRI Tractography Study
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Hamilton Health Sciences Corporation
Occupational Noise Exposure
OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION
This study aims to investigate the effects of occupational noise exposure on hearing and auditory functions among individuals working in noisy environments.
- Trial name
- NCT07806123
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
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