Clinical trials: WOUNDS INJURIES
Wounds
Impact of Oxidized Silver Wound Dressings on Wound Bacteria
Chronic non-healing wounds considerably impact quality of life in affected patients and are a substantial burden on the Canadian health care system.
- Trial name
- NCT02662101
- Testing
- Exsalt SD7, Exsalt T7 Wound Dressing
- Volunteers
- 17 people
- Sponsor
- Exciton Technologies Inc.
Spinal Cord Injury
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
This study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury.
- Trial name
- NCT06691165
- Testing
- Low oxygen therapy (LOT)
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Glen Foster
Ankle Sprain
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
The safety and the efficacy of the Esflurbiprofen Hydrogel Patch will be assessed in comparing with placebo in the treatment of acute pain due to ankle sprain
- Trial name
- NCT02729207
- Testing
- Esflurbiprofen Hydrogel Patch
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Spinal Cord Injuries
Electrical Stimulation for Spasticity in Spinal Cord Injury
This study examines the immediate and long-term effects of lumbosacral TENS on spasticity and residual voluntary force control in spinal cord injury in comparison to no TENS.
- Trial name
- NCT05103436
- Testing
- TENS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury
The purpose of this study is to assess if a zoledronic acid injection can alter the trajectory of joint degeneration following an acute anterior cruciate ligament (ACL) injury.
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis Knee
- Trial name
- ZAPOA (NCT05204836)
- Testing
- Zoledronic Acid Injection
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Calgary
Acupuncture, Mild Traumatic Brain Injury
Acupuncture for Mild Traumatic Brain Injury：A Functional Magnetic Resonance Imaging Study
The overall goal of this study is to examine if acupuncture intervention can reduce the post-concussion symptom (PCS), and affective and cognitive complaints among mild traumatic brain injury (TBI).
- Conditions
- Acupuncture, Mild Traumatic Brain Injury, MRI
- Trial name
- NCT02868671
- Testing
- acupuncture
- Where
- China
- Volunteers
- 66 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Trauma
Optimal Fluid Resuscitation for Trauma Patients
The purpose of this study is to determine if the overall fluid requirements for the first 24 hours after admission will be reduced with Hextend versus a standard of care crystalloid resuscitation fluid.
- Trial name
- NCT00527098
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Miami
Diabetic Foot Ulcers, Venous Stasis Ulcer
Negative Pressure Wound Therapy Registry
The goal of the Negative Pressure Wound Therapy Registry (NPWTR) for Wounds is to provide real world patient data from electronic health records submitted to meet Stage 2 Meaningful Use in order to understand the effectiveness…
- Conditions
- Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence
- Trial name
- NPWTR (NCT02467998)
- Testing
- NPWT
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- U.S. Wound Registry
TBI Traumatic Brain Injury, Enteral Nutrition Therapy
Effect of Enteral Formula (Commercial vs. Homemade) on Muscle Mass in Trauma Brain Injury
This randomized controlled clinical trial aims to determine whether there are differences in muscle mass (MM) in patients with traumatic brain injury who receive enteral nutrition based on polymeric formulas (homemade formula…
- Conditions
- TBI Traumatic Brain Injury, Enteral Nutrition Therapy, Critical Illness
- Trial name
- NCT06949163
- Testing
- Homemade formula, Commercial formula
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital General "Dr. Miguel Silva" de Morelia
Pressure Ulcer, Wounds
Wound Powder for Pressure Ulcers at End-of-life
This study will test a special powder for ulcers caused by a variety of conditions such as pressure that sometimes happen when a person is at the end of life.
- Trial name
- RGN107 (NCT02008487)
- Testing
- Wound powder application
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
Mild Traumatic Brain Injury
Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI
Veterans with mild traumatic brain injury continue to deal with symptoms that interfere with their ability to engage in productive activities.
- Trial name
- NCT04044456
- Testing
- Goal Management Training, Attention Training, Brain Health Workshop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Hypocalcemia
Clinical Assessment of Low Calcium In traUMa (CALCIUM)
Major trauma frequently occurs in the deployed, combat setting and is especially applicable in the recent conflicts with explosives dominating the combat wounded.
- Trial name
- CALCIUM (NCT05885256)
- Testing
- Amending current standard trauma order set
- Where
- United States
- Volunteers
- 391 people
- Sponsor
- Brooke Army Medical Center
Head and Neck Cancer, Oropharyngeal Carcinoma
Thermotherapy for Locally Advanced Head and Neck Cancer
Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor.
- Conditions
- Head and Neck Cancer, Oropharyngeal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Cancer
- Trial name
- TANCA-I (NCT06761937)
- Testing
- Thermotherapy, radiotherapy
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Erasmus Medical Center
Shoulder Injuries
Use of the Efisiotrack System for Monitoring Patients With Shoulder Orthopedic Injuries
To evaluate the effect on clinical variables of monitoring exercises prescribed for shoulder injury rehabilitation with the eFisioTrack platform in patients of the Rehabilitation Service at University Hospital of Elche.
- Trial name
- NCT06026137
- Testing
- eFisioTrack Group, Excercises Group
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Lateral Epicondylitis
Bundang Rehabilitative Impact Study of the Elbow Epicondylitis
This study is to assess the safety and effect of polydeoxyribonucleotide(PDRN) on the lateral epicondylitis with ultrasonography-guided injection of the PDRN or dextrose solution.
- Trial name
- BundangRISEe (NCT02492945)
- Testing
- 3ml-Rejuvinex, 3ml-15%-dextrose solution
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Burns, Parents
Investigation of the Impact of Burn Injury on Parents
Burn injuries are related to longer hospital stay. Patients who have a burned child are affected prolonged hospitalization. Social life and quality of life are affected by burn injuries.
- Trial name
- NCT03838172
- Testing
- Family impact scale
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Acquired Brain Injury
Exploring the Use of the Cognitive Orientation to Daily Occupational Performance Approach (CO-OP) With Children, Teenagers and Young Adults With Executive Functions Deficits Following Severe Acquired Brain Injury
Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- REFECO-OP (NCT04560777)
- Testing
- CO-OP intervention
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Trauma, Mental Health Disorder
Investigating the Effect of Evidence-based Treatment for Post-traumatic Stress Disorder Among Youth
Trauma-focused cognitive-behavioral therapy (TF-CBT) is an evidence-based practice (EBP) for the treatment of posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) among children and adolescents.
- Conditions
- Trauma, Mental Health Disorder, PTSD, Implementation
- Trial name
- NCT05226481
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Pediatric, Fracture
Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery
This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective…
- Conditions
- Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction
- Trial name
- NCT06429267
- Testing
- Bioabsorbable Screw, Metal/Titanium Screw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Anesthesia, Traumatic Brain Injury
The Effect of Mannitol Volume With Changes in Osmolarity in Traumatic Brain Injury
This observational study is designed to research the effect of mannitol volume administration with changes in osmolarity in patients with traumatic brain injury to guide the safe use of mannitol in these patients.
- Trial name
- NCT06846307
- Testing
- Mannitol
- Where
- Indonesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universitas Diponegoro
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