Clinical trials: Water
Dehydration, Cardiac Output
Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics
The purpose of this study is to non-invasively study the reflective changes in cardiac output as response to fluid therapy in the pediatric moderate hypovolemia/dehydrated pediatric patients using sub-q rehydration using Hylenex…
- Conditions
- Dehydration, Cardiac Output, Pediatrics
- Trial name
- Hylenex (NCT01139294)
- Testing
- Hylenex
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Urinary Bladder, Overactive
Brain Areas Involved in Bladder Filling and Contraction
Overactive Bladder syndrome (OAB) is a medical condition with symptoms of urgency, with or without incontinence, usually with frequency and nocturia, with no proven infection or obvious pathology 1.
- Trial name
- NCT02477241
- Testing
- Uroflowmetry, fMRI
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Breast Cancer Patients, Chemotherapy Induced Peripheral Neuropathy (CIPN)
The Effect of Cold Salt Water Foot Bath on the Development Of Chemotherapy-Induced Peripheral Neuropathy
This prospective, randomised, controlled study was designed to evaluate the effectiveness of salt and unsalted cold water foot baths in preventing chemotherapy-induced peripheral neuropathy (CIPN) in patients receiving…
- Conditions
- Breast Cancer Patients, Chemotherapy Induced Peripheral Neuropathy (CIPN), Paclitaxel-induced Peripheral Neuropathy
- Trial name
- NCT06964802
- Testing
- Cold salt water foot bath, Cold water foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Tuba Eryiğit
Oropharyngeal Dysphagia
Investigation of a Free Water Protocol
Hypothesis: Use of a Free Water Protocol (FWP) will improve patient satisfaction scores (Dysphagia Handicap Index), will not increase the risk of aspiration pneumonia/pneumonitis, and will result in improved oral hygiene (as…
- Trial name
- NCT06309602
- Testing
- Free Water Protocol, Control / Standard Care
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Poudre Valley Health System
Hyperlipidemias
Efficacy and Safety of Portable Hydrogen Rich Water Machine is Used for Adjuvant Treatment of Patients With Hyperlipidemia
In the past 30 years, the blood lipid level of the Chinese population has gradually increased, and the prevalence of dyslipidemia patients has increased significantly.
- Trial name
- NCT06301451
- Testing
- General dietary guidance and hydrogen water prepared by portable hydrogen rich water machine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Sun Jia
Exercise Therapy
Effects of a Metronome on Functional Outcomes in Aquatic Therapy
The purpose of this study is to determine if the use of a pacing device, a metronome, improves functional outcome measures in aquatic therapy when compared to a control group.
- Trial name
- NCT03801772
- Testing
- Metronome
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Aultman Health Foundation
Benign Prostatic Hyperplasia (BPH)
REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men
The study objective is to compare water vapor thermotherapy with the REZŪM™ System to dual drug therapy for the treatment of symptomatic benign prostatic hyperplasia refractory to alpha-blocker monotherapy in sexually active men.
- Trial name
- VAPEUR (NCT04838769)
- Testing
- REZŪM, alpha blocker and 5-alpha reductase inhibitor
- Where
- 21 sites in Australia, France
- Volunteers
- 155 people
- Sponsor
- Boston Scientific Corporation
Obesity
Water Induced Thermogenesis in Obese Children
Drinking water is largely advocated for obesity prevention and management. Recent studies have suggested that water has a thermogenic effect, this has not been examined in children.
- Trial name
- NCT00794469
- Testing
- Water
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hyperkalemia
Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.
It is hypothesized that ZS is more effective than placebo control (alternative hypothesis) in maintaining mean double-blind randomized maintenance phase (DBRMP) Day 8-29 serum potassium levels (3.5 - 5.0 mmol/l, inclusive) among…
- Trial name
- NCT02088073
- Testing
- Sodium zirconium cyclosilicate
- Where
- 46 sites in United States, Australia and 1 more
- Volunteers
- 258 people
- Sponsor
- ZS Pharma, Inc.
Overweight
Promoting Water Consumption for Prevention of Overweight in School Children in a Controlled Intervention Trial
A major goal in public health is to find effective, feasible and simple programs for overweight prevention among children. This controlled intervention study evaluates a simple environmental and behavioral modification for its…
- Trial name
- trinkfit (NCT00554294)
- Testing
- environmental and behavioral change
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- Research Institute of Child Nutrition, Dortmund
Acute Kidney Injury, Drug Toxicity
Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate
This retrospective observational study will evaluate high-dose methotrexate patterns of use, supportive care measures used during high-dose methotrexate chemotherapy, along with the incidence of delayed elimination of…
- Trial name
- NCT05899751
- Testing
- High-dose methotrexate, Glucarpidase
- Where
- 5 sites in France, Italy and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Protherics Medicines Development Limited
Hyponatremia
0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children
The primary objective of this study is to compare the mean serum sodium at 48 hours following the initiation of therapy with either 0.45% NaCl/dextrose 5% or 0.9% NaCl/dextrose 5%, in children requiring maintenance IV fluid…
- Trial name
- NCT00632775
- Testing
- Hypotonic (0.45% NaCl/5% dextrose) IV maintenance fluids, Isotonic (0.9% NaCl/5% dextrose) IV maintenance fluids
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- The Hospital for Sick Children
Menopausal Women
A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.
The goal of this study is to investigate the effect of pollen extracts on menopausal symptoms in healthy women The main question it aims to answer is: What is the difference in change in severity of menopausal symptoms as…
- Trial name
- NCT06889753
- Testing
- Graminex WSPE, Graminex LSPE
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Graminex LLC
Wound Infection Rate After Surgery, Impact of Wound Infection on Pain and Wound Healing
Impact of Preoperative Local Water-Filtered Infrared-A (wIRA) Irradiation on Postoperative Wound Healing
The purpose of this study is to dermine whether local-water filtered infrared-A (wIRA) irradiation can reduce postoperative wound infection.
- Trial name
- Hydrosun (NCT01654679)
- Testing
- wIRA irradiation, visible light only
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- German Research Foundation
Osteoporosis Risk
Evaluation of the Effects of Bicarbonate-calcium Water in Premenopausal and Postmenopausal Women as a Prevention of Osteoporosis
The goal of this clinical trial is to evaluate the effect of bicarbonate-calcium water for the prevention of osteoporosis. Participants are women in pre- or post- menopausal state.
- Trial name
- NCT05854342
- Testing
- bicarbonate-calcium water
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salerno
Cognition Disorders
PET Scan to Map the Areas of the Brain Involved in Planning
Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal…
- Trial name
- NCT00001363
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Water Stress, Body Water Dehydration
Influence of Osmotic Stimulation of Vasopressin on Autonomic Function
The regulation of total body water that defines human hydration status is a complex and dynamic process. Current methods of assessing hydration status (e.g.
- Trial name
- NCT04233606
- Testing
- Hypertonic Saline, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Anaphylaxis Food
Predicting Peanut Anaphylaxis and Reducing Epinephrine
This research study is testing a new way to look for the early stages of anaphylaxis. Eligible participants will have a small monitor (transepidermal water loss) placed on the forearm during a food challenge (for peanut…
- Trial name
- PrePARE (NCT05696236)
- Testing
- Transepidermal water loss (TEWL) monitor and stopping rules, Monitor (TEWL) without stopping rules
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Age Problems, Cognitive Impairment
Feasibility Aquatic Physical Exercise to Reduce Falls in Institutionalized Elderly
This is a pilot randomized control trial with single blinding of the assessor that will be conducted in two nursing homes residence to evaluate the applicability of a physical exercise program performed in an aquatic environment…
- Conditions
- Age Problems, Cognitive Impairment, Elderly, Postural Balance
- Trial name
- PrePhysFalls (NCT03019211)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Post-COVID / Long-COVID, POST-Covid 19
Effects of Hydrotherapy During Post-COVID-19 Rehabilitation
This randomized controlled study evaluates the effects of cold water hydrotherapy as an adjunct to standard rehabilitation in patients with Post-COVID Syndrome.
- Conditions
- Post-COVID / Long-COVID, POST-Covid 19, Post COVID Syndrome, Post-COVID Condition
- Trial name
- HydroCoVital A (NCT07013903)
- Testing
- Standard rehabilitation plus cold water hydrotherapy, Standard rehabilitation only
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
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