Clinical trials: Water Treatment
Hyperkalemia, Chronic Kidney Failure
Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis Patients
The purpose of this trial is to determine if sodium polystyrene sulfonate (SPS) is an effective treatment of mild hyperkalemia in chronic kidney disease patients followed at a pre-dialysis or nephrology outpatient clinic.
- Trial name
- SKIP (NCT02065076)
- Testing
- Sodium polystyrene sulfonate, Lactose with carob gum
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Healthy Participants
A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants
The primary objective of the study is to evaluate the pharmacokinetics (PK) of AMG 510 administered as 8 x 120-mg tablets and as water dispersion in healthy participants.
- Trial name
- NCT05571163
- Testing
- AMG 510
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Amgen
Transurethral Resection of Prostate Syndrome
Prophylaxis Versus Treatment for TURP Syndrome.
This study is designed to investigate the usage \& effects of prophylactic HS preloading, with two different concentrations, to combat the expected dilutional hyponatremia induced by irrigating fluid absorption and to prevent the…
- Trial name
- NCT03428451
- Testing
- NaCl 3% HS, NaCl 0.9% NS
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahmed Mohamed ELbadawy
Hypernatremia
Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe Hypernatremia
This study will evaluate the efficacy and safety of rapid intermittent correction and slow correction with an electrolyte-free solution in patients with severe hypernatremia (glucose-corrected serum sodium, ≥ 155 mmol/L).
- Trial name
- SALSAII (NCT04949139)
- Testing
- Dextrose 5% in water
- Where
- South Korea
- Volunteers
- 178 people
- Sponsor
- Seoul National University Hospital
Hyponatremia, Subarachnoid Hemorrhage
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage
Hyponatremia is defined as a plasma sodium concentration below 135 mmol / L. This is a common occurrence (20-50%) during subarachnoid hemorrhage (SAH). Its appearance is often associated with vasospasm.
- Conditions
- Hyponatremia, Subarachnoid Hemorrhage, SIADH
- Trial name
- NAT-URE (NCT04552873)
- Testing
- Urea
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Grenoble
Hyperparathyroidism, Secondary
Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis
This study is designed to assess the efficacy and safety of etelcalcetide (AMG 416) compared with placebo in the treatment of SHPT in CKD patients receiving hemodialysis.
- Trial name
- NCT01788046
- Testing
- Etelcalcetide
- Where
- 106 sites in United States, Australia and 13 more
- Volunteers
- 515 people
- Sponsor
- Amgen
Kidney Failure, Chronic
Lung Water by Ultrasound Guided Treatment in Hemodialysis Patients (The Lust Study).
Volume overload is a leading risk factor for death and cardiovascular events in end stage renal disease patients maintained on chronic dialysis, particularly in those with myocardial ischemia and heart failure which represent a…
- Trial name
- LUST (NCT02310061)
- Testing
- Extra-vascular lung water measurements by ultrasound (LW-US), Standard protocol of fluid management in hemodialysis
- Where
- 19 sites in France, Germany and 7 more
- Volunteers
- 383 people
- Sponsor
- Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy
Household Water Treatment, Waterborne Illness
Healthy Networks Water Treatment Study
This study is a non-randomized double cohort study evaluating the impact of social network-based water treatment education on sustained household water treatment behaviors over 12 months of follow up.
- Trial name
- HNWT (NCT01907945)
- Testing
- Microclinic Water Program, Household education
- Where
- Kenya
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Hepatocellular Carcinoma
Comparison of Two Solvents Used With Chemotherapy Agent for Transarterial Chemoembolization of Hepatocellular Carcinoma
TACE is considered the standard treatment for unresectable HCC and is widely used as a palliative treatment. However there is no consensus of the protocol of TACE.One of the variation is does the stability of the suspension by…
- Trial name
- NCT01259414
- Testing
- Solvent with specific gravity less than lipiodol, Solvent with specific gravity equivalent to lipiodol
- Where
- China
- Volunteers
- 812 people
- Sponsor
- Sun Yat-sen University
Adolescent Anorexia Nervosa
Treatment Trial of Thermoregulatory Disturbances in Adolescent Anorexia Nervosa Patients With Either Ginger Powder Footbaths or Warm Water Footbaths
A study to explore whether warm water footbaths with added ginger powder can improve thermoregulatory processes in adolescent anorexia nervosa patients and provide them with an increase in subjective feeling of warmth.
- Trial name
- NCT03886207
- Testing
- ginger powder footbath, warm water only footbath
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Benign Prostatic Hyperplasia
Single Center Comparative Trial of Trans-Perineal Laser Ablation Vs Water Vapor Ablation
The primary aim of this clinical trial is to determine whether one of the two methods under investigation, TPLA or WVA, is superior in the treatment of BPH.
- Trial name
- NCT06794333
- Testing
- Transperineal laser Ablation, Rezum Vapor Therapy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Pisa
Diabetes Type 2, Weight Gain
Effects of Insulin Detemir and NPH Insulin on Renal Handling of Sodium, Fluid Retention, and Weight in Type 2 Diabetic Patients
Hypothesis: Changing type 2 patients treatment from Insulin Insulatard to Insulin Detemir will increase their excretion of sodium in the urine and thereby decrease their extracellular volume and body weight.
- Trial name
- Le-Na (NCT00742976)
- Testing
- Insulin Detemir; Insulin Insulatard, Insulin Detemir, Insulin Insulatard
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dehydration
Subcutaneous vs Intravenous Hydration on Older Adults
This study will evaluate the risk of adverse effects of intravenous hydration compared to subcutaneous hydration. Half of the patients will receive hydration by the subcutaneous route the other half by the intravenous route.
- Trial name
- SCIV (NCT03710408)
- Testing
- Intravenous hydration, Subcutaneous hydration
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- Aalborg University Hospital
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Post COVID-19 Condition, Post COVID-19 Condition (PCC)
Effects of Kneipp Hydrotherapy in Post-COVID-19 Patients
This randomized controlled study evaluates the effects of cold water hydrotherapy in patients with Post-COVID Syndrome. The primary aim is to assess changes in quality of life compared to an usual care setting without…
- Conditions
- Post COVID-19 Condition, Post COVID-19 Condition (PCC), Post COVID-19, Post COVID-19 Syndrome
- Trial name
- HydroCoVitalB (NCT07110714)
- Testing
- Cold water hydrotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Eggensberger OHG
Stomach Neoplasm, Intestinal Neoplasm
Multicentric Study an Endoscopic Treatment of Digestive Neoplasia by Submucosal Dissection Evaluation of a New Water Jet System
safety evaluation of endoscopic sub-mucosal dissection with nestis enki2 system. This system is a new water jet system which allows to perform Endoscopic submucosal dissection with a bifunctional catheter (injection and cutting).
- Conditions
- Stomach Neoplasm, Intestinal Neoplasm, Rectal Neoplasm
- Trial name
- NCT01910974
- Testing
- endoscopic sub-mucosal dissection
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hôpital Edouard Herriot
Distress, Emotional, COVID-19
The Effectiveness of Natural Resources for Reducing Stress
High levels of stress cause serious health problems and reduce the quality of life. There is a lack of research proving the use of natural resources for the treatment or prevention of the stress and recovery from post Covid-19…
- Trial name
- LUGISES (NCT06018649)
- Testing
- Balneotherapy plus complex, Combined nature resources treatment, Nature therapy procedure
- Where
- Lithuania
- Volunteers
- 330 people
- Sponsor
- Klaipėda University
Infantile Malignant Osteopetrosis
A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant Osteopetrosis
The primary objective of this Phase 1 study is to evaluate the therapeutic safety and feasibility of the investigational product (IP), RP-L401.
- Trial name
- NCT04525352
- Testing
- RP-L401
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Hyperparathyroidism
The Effects of Alendronate After Cure of Primary Hyperparathyroidism
We are investigating whether, after surgical cure of primary hyperparathyroidism, alendronate provides even greater beneficial skeletal effects than parathyroidectomy alone.
- Trial name
- AlenPostPara (NCT00359385)
- Testing
- Alendronate 70mg weekly
- Where
- United States
- Sponsor
- Columbia University
Healthy
Magnesium Effects in Apheresis
This study will determine whether magnesium replacement during apheresis can decrease side effects that donors commonly experience.
- Trial name
- NCT00040235
- Testing
- magnesium
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)