Clinical trials: Water Treatment
Skin Barrier to Water Loss, Microbial Colonization
Oral Lactobacillus Reuteri for Skin Barrier Dysfunction in Obesity
This clinical trial aims to evaluate the safety and efficacy of oral Lactobacillus reuteri supplementation for treating obesity-induced skin barrier impairment in individuals aged 18-40 with a BMI ≥30.
- Trial name
- NCT07512050
- Testing
- Oral Lactobacillus reuteri group, Oral administration of inactive Lactobacillus reuteri group
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Erectile Dysfunction
Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Versus To Viagra® Oral Tablet.
This study will evaluate if an orally disintegrating tablet of sildenafil will have similar pharmacokinetic properties as the conventional tablet of sildenafil.
- Trial name
- NCT01254383
- Testing
- Sildenafil Tablet, Sildenafil ODT
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Neuropathies
The Use of a Water Soluble Under the Tongue (Sublingual) CBD Tablet for Treating Pain Associated With Diabetic Peripheral Neuropathy
Use of Cannabidiol for the treatment of Diabetic Neuropathic Pain.
- Trial name
- NCT04088929
- Testing
- CBD
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pure Green
Osteoarthritis, Knee, Pain
THERMARTHROSE: Gonarthrosis and Water Cure
The main objective of this study is to evaluate the therapeutic effect of a thermal treatment on gonarthrosis, with an increase of the number of patients presenting a clinically significant improvement.
- Trial name
- NCT00348777
- Testing
- thermal cure, 3 days access to watering place at 6 months
- Where
- 3 sites in France
- Volunteers
- 462 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Xerosis
Clinical Therapeutic Potential of Novel Microbiome LP-51 on Xerosis Individual Based on Xerosis-microbiome Index
The purpose of this clinical trial is to assess the skin hydration and transepidermal water loss improvement, pruritus relief, and microbiome alteration effects of a Lactobacillus sp.
- Trial name
- NCT06706050
- Testing
- Microbiome Therapeutic LP-51
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Ho-Yeon Song
Hyperkalemia, Chronic Kidney Failure
Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis Patients
The purpose of this trial is to determine if sodium polystyrene sulfonate (SPS) is an effective treatment of mild hyperkalemia in chronic kidney disease patients followed at a pre-dialysis or nephrology outpatient clinic.
- Trial name
- SKIP (NCT02065076)
- Testing
- Sodium polystyrene sulfonate, Lactose with carob gum
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Low Back Pain
Plus Deep Water Running on Low Back Pain
Objectives: To evaluate the effect size on non-specific chronic low back pain (CLBP) of evidence-based physiotherapy (EBP) with and without the addition of deep water running (DWR) on pain, physical disability and general health…
- Trial name
- +DWR (NCT00888524)
- Testing
- GP in Physio, GP in Physio plus DWR
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- University of Malaga
Acute Diarrhoea
Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children
The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water.
- Trial name
- NCT01376440
- Testing
- household water treatment
- Where
- Ethiopia
- Volunteers
- 845 people
- Sponsor
- Haramaya Unversity
Acute Kidney Injury, Renal Insufficiency,Chronic
Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial
This study is testing whether finerenone, when compared to placebo, is a tolerable and safe intervention when administered in patients with acute kidney injury (AKI).
- Conditions
- Acute Kidney Injury, Renal Insufficiency,Chronic, Kidney Diseases
- Trial name
- FiPAKI (NCT07775482)
- Testing
- Finerenone (BAY94-8862 ) 10 mg
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Jean-Maxime Côté
Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment
Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension
Primary aldosteronism (PA) is characterized by hypertension, frequent hypokalaemia, and an inappropriately high aldosterone-to-renin ratio (ARR).
- Conditions
- Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment, Adrenalectomy
- Trial name
- ADERADHTA2 (NCT07470580)
- Testing
- RFA -radiofrequency ablation, Adrenalectomy
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Hypocalcemia
Teriparatide (Forteo) in the Treatment of Patients With Postoperative Hypocalcemia
Primary Objective: -To identify the optimal dose of a seven-day course of twice-daily teriparatide as compared to standard therapy for hypocalcemia in patients after total thyroidectomy and/or extensive neck dissections…
- Trial name
- NCT00623974
- Testing
- Teriparatide (Forteo), Calcium, Calcitriol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center
Stroke, Dehydration
Neuroprotective Therapy and Therapeutic Target in Emergency Department
The investigators studied laboratory measurements and previously identified risk factors to identify factors predictors of early deterioration following stroke.
- Trial name
- NCT02143596
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- Chang Gung Memorial Hospital
Gingival Health
The Effects of Using Water Flosser Versus Interdental Brush on Gingival Health in Patients With Mandibular Bonded Retainer
This randomized controlled trial aimed to investigate and compare the effects of employing a water flosser versus an interdental brush on the gingival health of individuals with mandibular bonded retainers.
- Trial name
- NCT07054203
- Testing
- Water Flosser, Interdental Brush
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hyperkalemia, Renal Insufficiency, Chronic
Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects
This is a multicentre, 2-part, single-blind, randomised, withdrawal, placebo-controlled study, that includes a 4-week patiromer treatment phase (Part A) followed by an 8-week randomised placebo-controlled withdrawal phase (Part…
- Trial name
- Patiromer JADE (NCT05136664)
- Testing
- Patiromer Powder for Oral Suspension (Part A), Patiromer Powder for Orals Suspension (Part B)
- Where
- 28 sites in China
- Volunteers
- 262 people
- Sponsor
- Vifor Fresenius Medical Care Renal Pharma
Survival, Prosthesis
Survival Rate of All Ceramic Restorations Treated With Air-Water-Blasting Protocol
This study evaluates retrospectively the survival rate of all-ceramic restorations, cemented using AWB technique (test) compared to those cemented with conventional technique (control)
- Trial name
- NCT03523364
- Testing
- dental restorations
- Where
- Italy
- Volunteers
- 131 people
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Hyperkalemia
IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors
There are limited data regarding the burden of hyperkalaemia in patients attending emergency departments (ED) or who are hospitalised (excluding those already receiving dialysis).
- Trial name
- IMPRESS (NCT04510792)
- Testing
- No intervention
- Where
- United Kingdom
- Sponsor
- Portsmouth Hospitals NHS Trust
Diarrhea, Communicable Diseases
Automatic Chlorination and Child Health in Urban Bangladesh
Municipal water networks within industrialized countries typically rely on centralized treatment to manage piped water quality. Optimal water quality at the tap, however, requires well-maintained piped distribution networks, and…
- Trial name
- NCT02606981
- Testing
- Water chlorination by the Flogenic, Active control, vitamin C dosing into water
- Where
- Bangladesh
- Volunteers
- 1,549 people, healthy volunteers welcome
- Sponsor
- Stanford University
Dehydration, Acute Gastroenteritis
Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)
To compare length of stay (LOS) of pediatric patients in a pediatric emergency room presenting with Gastroenteritis treated with IV rehydration versus oral Speedlyte rehydration.
- Trial name
- NCT03562702
- Testing
- Standard IV Rehydration Therapy, Oral Rehydration Therapy (ORT)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Hyponatremia
International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia
This study will assess the safety of long-term tolvaptan use in patients previously enrolled in shorter-term Phase 3 studies and gather information on the natural history of hyponatremia in the context of tolvaptan therapy and…
- Trial name
- NCT02449044
- Testing
- Tolvaptan
- Volunteers
- 111 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Fibromyalgia
Effects of Hydrotherapy on Physical Function and Quality of Life of Women With Fibromyalgia
Fibromyalgia Syndrome (FS) is one condition that most affects functional performance, especially in women, due to alterations in the entire musculoskeletal system.
- Trial name
- NCT01839305
- Testing
- Hydrotherapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mariana Arias Avila