Clinical trials: Water Treatment
Scars, Keloids
Silicone vs Pirfenidone in the Treatment of Hypertrophic Scars and Keloids
Justification: Keloid scars are a major medical and cosmetic problem, especially in darker skin types that predominate in Mexico. It is estimated that hypertrophic scars affecting from 1.5 to 4.5% of the general population.
- Conditions
- Scars, Keloids, Hypertrophic Scar
- Trial name
- NCT06909812
- Testing
- pirfenidone 8% gel, silicon gel
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
Hepatocellular Carcinoma
Comparison of Two Solvents Used With Chemotherapy Agent for Transarterial Chemoembolization of Hepatocellular Carcinoma
TACE is considered the standard treatment for unresectable HCC and is widely used as a palliative treatment. However there is no consensus of the protocol of TACE.One of the variation is does the stability of the suspension by…
- Trial name
- NCT01259414
- Testing
- Solvent with specific gravity less than lipiodol, Solvent with specific gravity equivalent to lipiodol
- Where
- China
- Volunteers
- 812 people
- Sponsor
- Sun Yat-sen University
Pollution; Exposure
Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water
Approximately 34 million Americans rely on private wells to supply their drinking water. Private wells are excluded from the Safe Drinking Water Act.
- Trial name
- NCT05395663
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Humans, Young Adults
Analysis of the Effects on Human Tissues After Application of Therapeutic Modalities.
As a therapeutic modality, cryotherapy is highly used for soft tissue damage control during acute and subacute stages. Cryotherapy is able to reduce pain, inflammatory condition, muscle spasm, nerve conduction, metabolic rate…
- Conditions
- Humans, Young Adults, Health
- Trial name
- NCT03414346
- Testing
- Exclusively ice pack, Ice pack added 10% of water, Ice pack added 100% of water
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alessandro Haupenthal
Hyponatremia, Subarachnoid Hemorrhage
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage
Hyponatremia is defined as a plasma sodium concentration below 135 mmol / L. This is a common occurrence (20-50%) during subarachnoid hemorrhage (SAH). Its appearance is often associated with vasospasm.
- Conditions
- Hyponatremia, Subarachnoid Hemorrhage, SIADH
- Trial name
- NAT-URE (NCT04552873)
- Testing
- Urea
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Grenoble
Diabetic Peripheral Neuropathic Pain
Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA
The purpose of the study is to evaluate whether the DIA/NPR-6 is a better pain reliever in patients with diabetic neuropathic pain of the feet compared to placebo.
- Trial name
- NCT05766969
- Testing
- CBD/PEA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pure Green Pharmaceuticals Inc.
Small Cell Lung Cancer
Effect of Hyponatremia in Small Cell Lung Cancer
In this retrospective study, the investigators determined the frequency of hyponatremia in small cell lung cancer and the prognosis. 126 (27%) of 466 patients were hyponatremic.
- Trial name
- NCT04451460
- Volunteers
- 466 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Fatigue Syndrome
Hydrogen Water Intervention With Heart Rate Variability as an Outcome Biomarker in ME/CFS
The goal of this clinical trial is to learn if the OTC supplement, hydrogen water, works to treat the fatigue-related symptoms and functional limitations in adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- NCT07009691
- Testing
- Hydrogen water which is prepared from an OTC supplement.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stony Brook University
Kidney Failure, Secondary Hyperparathyroidism
Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol
The purpose of this non-inferiority study is to compare the safety and effectiveness of a mineral and bone disease treatment protocol based on calcitriol to one based on paricalcitol in hemodialysis patients using revised Kidney…
- Conditions
- Kidney Failure, Secondary Hyperparathyroidism, Hyperphosphatemia, Hypercalcemia
- Trial name
- ECRIP (NCT01725113)
- Testing
- Calcitriol, Paricalcitol
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Winthrop University Hospital
Low Back Pain, Obesity
WATERinMOTION Aquatic Exercise Program Compared to Land-Based Rehabilitation on Low-Back Pain Relief and Quality of Life
This randomized controlled trial compares the efficacy of an 8-week WATERinMOTION aquatic exercise program versus land-based rehabilitation for reducing low-back pain (LBP) and improving quality of life in sedentary…
- Conditions
- Low Back Pain, Obesity, Sedentary Behavior
- Trial name
- WATERinMOTION (NCT06946342)
- Testing
- "Aquatic Exercise Group", Land-Based Rehabilitation Group"
- Where
- Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
TMJ Disc Disorder
Comparison Between Different Concentrations of Ozone Gas as an Intra-articular Injection for Treatment of Internal Derangement of Tempromandibular Joint
The intra-articular injection is considered the first line of minimally invasive treatment of joint disease as it has an analgesic, antimicrobial effect and an immune system stimulating action as it is one of the most powerful…
- Trial name
- NCT07523451
- Testing
- Patients will be treated with 2ml ozone oxygen mixture with concentration 6 micron/ml, Patients will be treated with 2ml ozone oxygen mixture with concentration 12 micron/ml
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Systemic Lupus Erythematosus
Pulse Corticosteroid Therapy and Effect on Brain Water Diffusivity
In daily clinical use, pulse high dosis corticosteroids are used to treat cerebral edema in different pathological situations ( surgery, trauma, tumors...).
- Trial name
- NCT00527176
- Where
- Belgium
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Osteoarthritis of Multiple Joints
Effects of Sulfur Water and Mud Therapy on Serotonin Activity and Biochemical Parameters in Patients' Osteoarthrosis
This study is to examine the effects of sulfur bath and mud therapy on serotonin levels and other biochemical parameters in the blood of the osteoarthritis patients, as well as water the application of exercise in water effects…
- Trial name
- NCT04192162
- Testing
- Mud therapy application, Sulfur water application, Hygienic water
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Specialized Rehabilitation Hospital Banja Koviljaca
Hyponatremia, Syndrome of Inappropriate ADH (SIADH) Secretion
An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain
In 2014, the Spanish Sociedad Española de Oncología Médica (SEOM) algorithm for the treatment of hyponatraemia secondary to to syndrome of inappropriate antidiuretic hormone (SIADH) in oncology patients was developed.
- Trial name
- ALGA (NCT02548845)
- Where
- 4 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Otsuka Pharmaceutical Europe Ltd
Hypokalemia, Intensive Care Unit (ICU)
Management of Hypokalemia in Intensive Care Patients
Hypokalemia is a common electrolyte disorder in critically ill patients and may contribute to substantial morbidity and mortality if inadequately managed.
- Conditions
- Hypokalemia, Intensive Care Unit (ICU), Intensive Care Unit (ICU) Patients
- Trial name
- NCT07833722
- Testing
- Implementation of hypokalemia treatment algorithm
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Anadolu University
Chronic Fatigue Syndrome (CFS)
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This is a 16-week controlled treatment trial of an over-the -counter supplement, hydrogen water, for individuals with ME/CFS patients. An active treatment condition will be compared to a placebo-control condition.
- Trial name
- ME/CFS (NCT07753122)
- Testing
- Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fred Friedberg
Hyperkalaemia
A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China
The study is a multi-center prospective (primary data) non-interventional cohort study which enrolls 1500 patients including new and ongoing users on SZC at Study Enrollment Day in real-world clinical practice.
- Trial name
- ACTUALIZE (NCT05271266)
- Where
- 27 sites in China
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Pelvic Pain
Study of Electro-kinetically Modified Water for the Treatment of Pain Associated With Endometriosis
The purpose of this study is to evaluate the efficacy of electro-kinetically modified water (EMW) beverage, consumed twice daily (BID) for 3 months in the management of endometriosis associated pain, and to evaluate the effect of…
- Trial name
- NCT02523794
- Testing
- Electro-kinetically Modified Water
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Revalesio Corporation
Head and Neck Cancer
Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients
The goal of this research study is to learn if home-use of devices to identify dehydration risk, when added to standard care, will help to lower hospitalizations and emergency room visits (and related costs) in patients with head…
- Trial name
- NCT02253238
- Testing
- Quality of Life Survey, Health Management Surveys, Monitoring Devices
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- M.D. Anderson Cancer Center
Hyperparathyroidism, Secondary
Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease on Hemodialysis
This study is designed to assess the efficacy and safety of etelcalcetide compared with placebo in the treatment of SHPT in patients with chronic kidney disease (CKD) receiving hemodialysis.
- Trial name
- NCT01785849
- Testing
- Etelcalcetide
- Where
- 118 sites in United States, Australia and 13 more
- Volunteers
- 508 people
- Sponsor
- Amgen