Clinical trials: Water Treatment
Benign Prostatic Hyperplasia (BPH)
STEAM-MAP 1 Study - Steam Therapy With MRI and AI-assisted Planning
The STEAM-MAP 1 Study is a single-arm, prospective feasibility trial evaluating the integration of MRI-transrectal ultrasound (TRUS) fusion guidance into Rezūm water vapor thermal therapy for men with symptomatic benign prostatic…
- Trial name
- NCT07663344
- Testing
- MRI-TRUS fusion-guided Rezūm therapy
- Where
- 3 sites in Hong Kong
- Volunteers
- 15 people
- Sponsor
- Chinese University of Hong Kong
Hyperkalemia
Lower vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department
This clinical trial aims to evaluate the safety and efficacy of a lower dose insulin compared to the conventional dose for treating mild to moderate hyperkalemia, a condition characterized by elevated serum potassium levels below…
- Trial name
- IDK+ (NCT06724991)
- Testing
- Lower Dose Therapy, Conventional Dose Therapy
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Infertility
Sonographic Hysterosalpingography: Oil vs Water Based Media (SHOW Trial)
Performing fluoroscopic HSG with oil based contrast medium has been shown to increase pregnancy rates in a subfertile population.
- Trial name
- NCT03604549
- Testing
- Lipiodol UF, Saline
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Milton S. Hershey Medical Center
Pregnancy Related, Physical Activity
The Effects of Aerobic Water Exercise on Pregnancy
Objective: To assess the relationship between maternal cardiovascular capacity and aerobic water exercise during the gestational periods of hemodynamic overload.
- Trial name
- NCT01364506
- Testing
- Water aerobic exercise
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Post COVID-19 Condition, Post COVID-19 Condition (PCC)
Effects of Kneipp Hydrotherapy in Post-COVID-19 Patients
This randomized controlled study evaluates the effects of cold water hydrotherapy in patients with Post-COVID Syndrome. The primary aim is to assess changes in quality of life compared to an usual care setting without…
- Conditions
- Post COVID-19 Condition, Post COVID-19 Condition (PCC), Post COVID-19, Post COVID-19 Syndrome
- Trial name
- HydroCoVitalB (NCT07110714)
- Testing
- Cold water hydrotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Eggensberger OHG
Hypovolemic Hyponatremia
A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia
This is a randomized, double-blind, multicenter, placebo-controlled (standard therapy + placebo), phase 2 efficacy and safety study of the Tolvaptan tablets in treatment of patients with non-hypovolemic non-acute hyponatremia…
- Trial name
- NCT00664014
- Testing
- Tolvaptan
- Where
- 13 sites in China
- Volunteers
- 241 people
- Sponsor
- Otsuka Beijing Research Institute
Healthy
Bioequivalence Between WE 941 OD and Brotizolam (Lendormin®) Taken With Water in Healthy Adult Males
The bioequivalence of WE 941 OD tablets prepared in oral disintegrating tablet form and brotizolam conventional tablets (Lendormin® tablets), both taken with water, was evaluated in healthy adult male subjects.
- Trial name
- NCT02218645
- Testing
- WE 941 OD tablets, Brotizolam
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Vaginal Delivery, Perineal Swelling
Cold Magnesium Sulfate Solution for Perineal Swelling Following Vaginal Delivery
The purpose of this study is to compare the impact of treatment with cooled magnesium sulfate and cold water-soaked pads on perineal pain and swelling following vaginal delivery.
- Conditions
- Vaginal Delivery, Perineal Swelling, Perineal Pain
- Trial name
- MgSo4 (NCT02024256)
- Testing
- Cold pads soaked in Magnesium sulfate solution, Cold pads soaked in water
- Where
- 2 sites in Israel
- Volunteers
- 206 people
- Sponsor
- HaEmek Medical Center, Israel
Postoperative Complications
Bioelectrical Response to Preoperative Hydration in Colorectal Surgery
This single-center study will evaluate whether short-term changes in bioelectrical impedance measurements after a standardized preoperative intravenous fluid infusion can help predict complications following elective colon or…
- Trial name
- BIA-HYD-CRC (NCT07823530)
- Testing
- Ionolyte Balanced Isotonic Crystalloid
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University Hospital of Split
Breast Cancer, Hypercalcemia of Malignancy
Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium
The purpose of this study is to determine the potential of denosumab to treat Hypercalcemia of Malignancy in patients with elevated serum calcium who do not respond to recent treatment with intravenous bisphosphonates by lowering…
- Conditions
- Breast Cancer, Hypercalcemia of Malignancy, Colon Cancer, Endocrine Cancer
- Trial name
- NCT00896454
- Testing
- denosumab
- Where
- 24 sites in United States, Canada and 3 more
- Volunteers
- 33 people
- Sponsor
- Amgen
Alzheimer Disease
LIWA for Treatment of Alzheimer Patients
The thermal therapy combined with magnetic fields and ozone has a direct effect on patients with dementia and Alzheimer's with a regression of more than 60% of them
- Trial name
- LIWA (NCT02204969)
- Testing
- Lithia water, Transcranial Magnetic stimulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- American Society Of Thermalism And Climatology Inc
Hyponatremia
THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation
The purpose of this study is to determine the safety and efficacy of lixivaptan in the treatment of hyponatremia in patients with congestive heart failure.
- Trial name
- NCT00578695
- Testing
- lixivaptan
- Where
- 287 sites in United States, Argentina and 13 more
- Volunteers
- 652 people
- Sponsor
- CardioKine Inc.
Gastrointestinal Tumor
Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours
Gastrointestinal tumours (GITs) are the most common and fatal cancers worldwide; 96% of GITs show the microsatellite-stable (MSS)/proficient mismatch repair (pMMR) phenotype, and these tumours have a poor response to immune…
- Trial name
- HEAIS001 (NCT06022692)
- Testing
- Water-filtered infrared A radiation whole-body hyperthermia (HECKEL 3000MT-4T, Germany), tislelizumab (BeiGene, China) combined with PD-1 inhibitor
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Pengyuan Liu
All Cause Mortality
Heat Disinfection of HD Water Treatment System in Hemodialysis Patients
Hemodialysis (HD) may lead to increase inflammatory response through a number of mechanisms. HD-related inflammation is mainly due to underlying kidney disease, coexisting comorbidities, uremia per se, dialyzer membrane…
- Trial name
- NCT01138280
- Testing
- CWP 103H (Gambro, Sweden): a heat disinfection device
- Where
- Taiwan
- Volunteers
- 540 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Household Water Treatment, Waterborne Illness
Healthy Networks Water Treatment Study
This study is a non-randomized double cohort study evaluating the impact of social network-based water treatment education on sustained household water treatment behaviors over 12 months of follow up.
- Trial name
- HNWT (NCT01907945)
- Testing
- Microclinic Water Program, Household education
- Where
- Kenya
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Diarrhoea
An Efficacy Trial of a Gravity Fed Household Water Treatment Device as a Delivery System for Zinc
In low-income settings in developing countries unsafe water is one of the leading causes of high prevalence of waterborne diseases such as diarrhoea.Zinc is an essential trace element that has a critical role in growth and…
- Trial name
- NCT01481181
- Testing
- Zinc enriched water
- Where
- Kenya
- Volunteers
- 270 people
- Sponsor
- Wageningen University
Rhinitis Medicamentosa
A Study Comparing Proponent Solution - Nasal Spray (PSNS) With Salt Water for Treating Nasal Congestion Symptoms in Adults With Rebound Nasal Congestion While Weaning From Nasal Decongestant Sprays
The purpose of the study was to test if the PROPONENT® nasal spray works, if it is safe, and if it helps participants to stop using addictive nasal decongestant sprays.
- Trial name
- PROUD (NCT06817967)
- Testing
- PSNS, ISNS
- Where
- 7 sites in Norway
- Volunteers
- 194 people
- Sponsor
- Pharma Nordic AS
SIAD - Syndrome of Inappropriate Antidiuresis
Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction
Hyponatremia due to SIAD is frequently insufficiently corrected by fluid restriction alone, which remains the first-line therapy but is often poorly tolerated. Urea supplementation is recommended as second-line therapy.
- Trial name
- UREA-BIVA (NCT07528365)
- Testing
- urea
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Turin, Italy
Heart Failure; With Decompensation
Smart SCALEs With Bioimpedance Analysis for Treatment Guidance in Decompensated Heart Failure
In this trial the measurement of whole body water will be compared to the standard method of measuring the body weight as treatment guidance in patients with decompensated heart failure.
- Trial name
- SCALE HF (NCT03288701)
- Testing
- Seca medical Body Composition Analyser 515
- Where
- Switzerland
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Thirst
Treating Post-Operative Thirst With Flavoured Ice Lollies or Water - a Comparative Study to Improve Post-operative Discomfort
Patients are asked not to eat and drink before their operation, and the investigators know that this can make people feel thirstier when they wake up from their anaesthetic.
- Trial name
- THIRST (NCT06014216)
- Testing
- Flavoured ice lollies (popsicles), Water
- Where
- United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust