Clinical trials: Water Treatment
Infantile Malignant Osteopetrosis
A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant Osteopetrosis
The primary objective of this Phase 1 study is to evaluate the therapeutic safety and feasibility of the investigational product (IP), RP-L401.
- Trial name
- NCT04525352
- Testing
- RP-L401
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Osteoarthritis of the Hip or Knee
A Comparison of Kneipp Hydrotherapy With Conventional Physiotherapy in the Treatment of Osteoarthritis of the Hip or Knee: Protocol of a Prospective Randomised Controlled Clinical Trial
The study design consists of a prospective randomised controlled three-armed clinical trial, which will be carried out at a specialist clinic for integrative medicine, to investigate the clinical effects of hydrotherapy on…
- Trial name
- NCT00950326
- Testing
- Physiotherapy, Affusion, Affusion/ Physiotherapy
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Kneippsche Stiftungen
Hypercalcemia, Granuloma
Hypercalcemia After Paraffin Oil Injection
Today, there is an increased use of non-medical, invasive cosmetic treatments globally without sufficient awareness of possible health risks.
- Trial name
- NCT04292288
- Testing
- Biochemical observational
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Martin Blomberg Jensen
Chronic Fatigue Syndrome
Hydrogen Water Treatment for Chronic Fatigue Syndrome
The proposed placebo-controlled pilot study will examine hydrogen water as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). 25 subjects who meet strict criteria for ME/CFS will be recruited.
- Trial name
- H2CFS (NCT05013606)
- Testing
- Hydrogen water
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stony Brook University
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Healthy Volunteers
A Study Comparing Two Ways of Taking Olomorasib (LY3537982) in Healthy Participants
The main purpose of this study is to compare how much and how quickly olomorasib gets into the bloodstream when it is taken in 2 different ways, and to check for any side effects.
- Trial name
- NCT07794592
- Testing
- Olomorasib test, Olomorasib reference
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Hydrotherapy
Effects of Various Modalities Water Immersion on Veins
Objectives In this study the investigators examined the changes in common femoral vein (CFV) and great saphenous vein (GSV) calibre during thermo neutral water immersion (TNI), cold water immersion (CWI) and contrast water…
- Trial name
- NCT02677402
- Testing
- immersion
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Shivering
Shivering_Basel_Baden
Shivering is known to occur in around 40% of women as a side effect of neuraxial anaesthesia during caesarean section.Women undergoing caesarean section under neuraxial anaesthesia are randomised into either the treatment group…
- Trial name
- NCT04938219
- Testing
- Gloves filled with warm tap water
- Where
- 2 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Volunteers
Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral Tablet
The bioavailability of the oral disintegrating tablet formulations given without water will be similar to an equivalent dose of the standard oral tablet given with water.
- Trial name
- NCT00950404
- Testing
- Viagra 50 mg tablet, Formulation B ODT tablet 50 mg, Formulation C ODT tablet 50 mg
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Kidney Disease, Hypertension
Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)
This study determined the optimal starting dose of patiromer in treating hyperkalemia in participants with hypertension and diabetic nephropathy who were already receiving ACEI and/or ARB drugs, with or without spironolactone.
- Conditions
- Chronic Kidney Disease, Hypertension, Hyperkalemia
- Trial name
- AMETHYST-DN (NCT01371747)
- Testing
- patiromer, losartan, spironolactone
- Where
- 43 sites in Croatia, Georgia and 3 more
- Volunteers
- 324 people
- Sponsor
- Relypsa, Inc.
Preeclampsia Severe, Preeclampsia Postpartum
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia
The objective of the study is to determine whether administration of vitamin C (1.5g/6 hours) in the first three days post-partum reduces the amount of extravascular lung water assessed by lung ultrasound in patients with severe…
- Trial name
- NCT03451266
- Testing
- Vitamin C
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- University Medical Centre Ljubljana
Prostatic Hyperplasia
One-year Results After Single-center Water Vapor Thermal Therapy for Symptomatic Benign Prostatic Hyperplasia.
Objective: Rezūm vapor ablation is a minimally invasive treatment for benign prostatic hyperplasia (BPH) that uses injections of sterile water vapor directly into the prostate for tissue ablation.
- Trial name
- NCT06257654
- Testing
- REZUM
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Benign Prostatic Hyperplasia
Optimized Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia
Water vapor thermal therapy (Rezum) is a minimally invasive treatment for benign prostatic hyperplasia (BPH) that uses injections of sterile water vapor directly into the prostate for tissue ablation.
- Trial name
- NCT06607094
- Testing
- Rezum
- Volunteers
- 58 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Autosomal Dominant Polycystic Kidney Disease
Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common single gene disorder that is potentially fatal. ADPKD is caused by mutations in either of two genes (PKD1, PKD2).
- Trial name
- NCT00759369
- Testing
- Water prescription
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Kansas
Hypertension, Potassium Imbalance
Occurrence of Dyskalemia With Treatment for Hypertension
Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because…
- Trial name
- OK (NCT05155436)
- Testing
- Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
- Where
- Bangladesh
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- National Heart Foundation of Bangladesh
Cerebral Palsy
Changes in Land-Based Motor Function After Routine Hydrotherapy in Children With Cerebral Palsy
This retrospective observational study aims to describe changes in land-based motor function recorded before and after routine hydrotherapy among children with cerebral palsy.
- Trial name
- CP-HYDRO-RETRO (NCT07907445)
- Testing
- Routine Hydrotherapy (Aquatic Rehabilitation)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karabuk University
Chronic Low-back Pain (cLBP)
Effects of a Land and Aquatic Exercise-based Program on Pain, Mobility and Quality of Life in Patients With Chronic Low Back Pain
The goal of this randomized clinical trial] is to study the effect of a combined aquatic and land-based exercise program compared to an aquatic program on pain, functional disability, and quality of life in adults with chronic…
- Trial name
- NCT06641570
- Testing
- Aquatic Exercise Program, Land-based Exercise Program
- Where
- Portugal
- Volunteers
- 41 people
- Sponsor
- Instituto Politécnico de Leiria
Hyperkalemia, End Stage Renal Disease
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
The purpose of this study is to determine whether once-daily dosing of patiromer will reduce the frequency of hyperkalemic episodes in ESRD (end stage renal disease) study participants who receive conventional hemodialysis (HD).
- Trial name
- NCT03781089
- Testing
- Patiromer Oral Powder Product
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Pediatric, Efficiency
Optimisation of Solute Removal and Water Usage in Paediatric Haemodialysis
Children receiving chronic haemodialysis are typically treated with dialysis machines designed for adult patients. As a result, some devices do not allow the ideal blood or dialysate flow rates to be set for paediatric use.
- Conditions
- Pediatric, Efficiency, Hemodialysis Patient, Hemodialysis Treatment
- Trial name
- OptiPed (NCT07466459)
- Testing
- blood and dialysate sampling
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent