Clinical trials: Weakness
Intensive Care Unit Syndrome, Muscle Weakness
Inspiratory Muscle Training and Expiratory Muscle Thickness
the specific effect of IMT on expiratory muscle strength and abdominal wall thickness during weaning remains unclear. To address this significant research gap, the primary objective of our study was to evaluate the effect of IMT…
- Conditions
- Intensive Care Unit Syndrome, Muscle Weakness, Rehabilitation
- Trial name
- NCT06251791
- Testing
- conventional physiotherapy+ IMT, conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss
Blood Flow Restriction Training in Rehabilitation Patients
Occlusion training, resistance exercise performed with a specialized venous tourniquet, leads to beneficial changes in muscle at low resistance and minimal stress on the nearby joint.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
- Trial name
- NCT02174770
- Testing
- Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Brooke Army Medical Center
Urinary Incontinence, Pelvic Floor Muscle Weakness
Dose-response of Physical Exercise on Pelvic Floor Muscle Function in Postmenopausal Women With Urinary Incontinence
Urinary incontinence (UI) symptoms are highly prevalent among women, and menopause is one of the risk factors for UI. During the menopausal transition, not only the hormonal secretion is changed but also the level of physical…
- Trial name
- NCT04351750
- Testing
- general exercise, pelvic floor muscle training
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- National Cheng Kung University
Healthy Participants
Pain Inhibition With Neuromuscular Electrical Stimulation
The purpose of this study is to demonstrate the pain relieving effect of neuromuscular electrical stimulation that is applied for the purpose of increasing muscle force output.
- Trial name
- NCT05280522
- Testing
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New England
Sensorineural Hearing Loss, Vestibular Hypofunction
Optimizing Cochlear Implant Laterality in Patients With Unilateral Vestibular Weakness
In patients with symmetric hearing loss who meet traditional cochlear implant candidacy criteria yet demonstrate pre-operative unilateral vestibular weakness, the choice of which ear to implant may impact their post-operative…
- Trial name
- NCT07452653
- Testing
- Ipsilateral cochlear implantation in patients with unilateral vestibular hypofunction, Contralateral cochlear implantation in patients with unilateral vestibular hypofunction
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Shoulder Pain, Muscle Weakness
Effect of Kinesio Taping on Muscle Strength in Lower Trapezius
The purpose of this project is to investigate the effect of Kinesio tape on muscle strength of the lower trapezius in people with shoulder symptoms and decreased muscle strength in the lower trapezius - a randomized controlled…
- Trial name
- NCT02290730
- Testing
- Kinesio tape
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- Norwegian School of Sport Sciences
Heart Failure
Using Clonidine to Improve Leg Weakness in People With Heart Failure
People with heart failure often have weakness in their leg muscles. This study will determine whether the leg weakness is due to very high adrenaline levels and whether the medication clonidine can improve leg weakness.
- Trial name
- NCT00858845
- Testing
- Clonidine Patch
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Childhood Cancer, Muscle Weakness
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
The participants are being asked to take part in this trial, because the participant is a survivor of childhood cancer or agreed to be part of a volunteer group to understand the relation between cancer and cancer treatment and…
- Trial name
- NCT06819475
- Testing
- Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Physical function assessment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Fibromyalgia, Sarcopenia
Muscle Architecture and Muscle Strength in Fibromyalgia
The goal of this observational study is to determine whether there is decrease in muscle mass and muscle strength in Fibromyalgia Syndrome (FMS) patients in comparison to controls.
- Conditions
- Fibromyalgia, Sarcopenia, Muscle Weakness
- Trial name
- NCT06378788
- Testing
- Demographic information form, widespread pain index (WPI), symptom severity scale (SSS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Stroke, Chronic Stroke Patients
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- NCT07631078
- Testing
- kTMP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Magnetic Tides
Stroke Rehabilitation
Muscle Strength Loss In Stroke Individuals - Control Study
ABSTRACT The muscle strength (MS) is necessary to overcome the resistance encountered during the activity. The present study aims to determine MS loss in stroke individuals (SI).
- Trial name
- NCT04395209
- Testing
- assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
MUSCULAR AQUIRED WEAKNESS, Bioelectrical Impedance Analysis
The BIA and MUS in the Detection of Nutritional Status in Critically Ill Patients
Critically ill patients are characterized by wide variations in their carbohydrate, lipid, and protein metabolism. Such variations can lead to increase in their energy requirement with accelerated protein catabolism and…
- Conditions
- MUSCULAR AQUIRED WEAKNESS, Bioelectrical Impedance Analysis, Muscular Ultrasound
- Trial name
- BUS (NCT03924232)
- Where
- Italy
- Volunteers
- 97 people
- Sponsor
- University of Milan
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Muscle Weakness Conditions
Biomedical Instrumentation in the Study of Mirror Therapy in Elderly's Hands Motor Activity
Check if the Mirror therapy represents an effective method in improving the motor activity of the hands of institutionalized elderly.
- Trial name
- NCT02104102
- Testing
- Mirror Therapy, Kinesiotherapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Paraíba
Weaning Failure, Muscle Weakness
TESTO-TRIAL: Use of Testosterone in Critically Ill Patients
The objective of this study is to evaluate whether the use of the anabolic agent testosterone cypionate in critically ill patients, compared to placebo, increases the number of ventilator-free days
- Conditions
- Weaning Failure, Muscle Weakness, Mechanical Ventilation Complication, ICU Acquired Weakness
- Trial name
- TT (NCT06592144)
- Testing
- Testosterone cypionate (200mg/3ml), Sesame oil (3ml)
- Where
- Brazil
- Volunteers
- 94 people
- Sponsor
- Leticia Maria Defendi Barboza Marson
Hospitalized Patients, ICU Hospitalization
Virtual Reality in Intensive Care Unit: Patient Satisfaction, Clinical and Functional Outcomes, Feasibility
Background: Virtual reality is recognized as a progressive technology with the potential to enhance the rehabilitation process. Immersive virtual reality-based treatments can improve motor outcomes in physical rehabilitation…
- Conditions
- Hospitalized Patients, ICU Hospitalization, Intensive Care Unit-acquired Weakness
- Trial name
- NCT07089134
- Testing
- reabilitação fisioterapêutica tradicional, fisioterapia utilizando realidade virtual imersiva
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Hospital Sirio-Libanes
Oxidative Stress, Inflammation
Oxidative Stress and Nutritional Supplementation Intervention Study
A major means whereby oxidative stress promotes aging-related disease is by activating inflammatory pathways. Decreasing oxidative stress and inflammation should ameliorate many of the problems associated with aging, including…
- Conditions
- Oxidative Stress, Inflammation, Aging, Dementia
- Trial name
- Oxi-Stress (NCT01234506)
- Testing
- secoisolariciresinol diglucoside
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
EBV Infection
Study to Evaluate the Efficacy of 2LEBV® and 2LXFS® on Asthenia in Patients With an Epstein-Barr Virus Infection
Worldwide, 95% of adults are infected with Epstein-Barr Virus (EBV). These infections may cause different diseases. In most cases, EBV infection is asymptomatic because of a highly effective host immune response.
- Trial name
- EBVAST (NCT04308278)
- Testing
- 2LEBV® / 2LXFS®
- Where
- 8 sites in Belgium
- Volunteers
- 88 people
- Sponsor
- Labo'Life
Frailty Syndrome, Respiratory Muscle Weakness
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on diaphragmatic and respiratory muscle function in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Respiratory Muscle Weakness, Age-Related Frailty, Geriatric Health
- Trial name
- IMT-1 (NCT07258615)
- Testing
- Inspiratory Muscle Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
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