Clinical trials: Weakness
ICU Acquired Weakness, Diaphragmatic Injury
Transcutaneous Electrical Diaphragmatic Stimulation in Critically Ill Elderly Patients
Abstract..........................................................................................................04…
- Trial name
- NCT04565002
- Testing
- Transcutaneous Electrical Diaphragmatic Stimulation
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Centro Universitário Augusto Motta
LIVER CIRRHOSIS
Magnesium in Liver Cirrhosis
Several studies have shown in patients magnesium deficiency with liver cirrhosis. Patients with liver cirrhosis showed considerably reduced muscle strength and muscle magnesium.
- Trial name
- NCT01894867
- Testing
- magnesium
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Frailty Syndrome, COVID-19
Implementation of the Integrated Care of Older People App and ICOPE Monitor in Primary Care (ICOPE)
Introduction: The World Health Organization has launched the INSPIRE-ICOPE-CARE program towards healthy aging. It includes "intrinsic capacity", defined as "the composite of all the physical and mental capacities of an…
- Conditions
- Frailty Syndrome, COVID-19, Healthy Aging, Old Age; Debility
- Trial name
- ICOPE (NCT04413877)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Liege
Muscle Weakness
Nasotracheal Suction With Tiemann Catheter Compared to the Classic Technique With the Suction Catheter
The study compares the effectiveness of Tiemann and Suction catheters, with regard to attempts to enter the trachea and the time required for the procedure.
- Trial name
- NCT02261428
- Testing
- Catheter Tiemann, Suction catheter
- Volunteers
- 20 people
- Sponsor
- Grigoriadis Konstantinos
Implementation Science, Delirium
Behavioral Economic & Staffing Strategies in the ICU
The overarching goal of this study is to support the "real world" assessment of strategies used to foster adoption of several highly efficacious evidence-based practices in healthcare systems that provide care to critically ill…
- Conditions
- Implementation Science, Delirium, Critical Illness, Mechanical Ventilation Complication
- Trial name
- BEST-ICU (NCT06184945)
- Testing
- Realtime audit and feedback, RN Implementation Facilitator
- Where
- 3 sites in United States
- Volunteers
- 16,500 people
- Sponsor
- University of Nebraska
Lower Limb Burn, Muscle Weakness Condition
Comparing Effects of Whole Body Vibration and Resisted Training on Quadriceps Strength After Lower Limb Burns
Evaluate the therapeutic effect of Whole body vibration and Resistance training on strength of quadriceps post lower limb burn
- Trial name
- NCT06801301
- Testing
- whole body vibration, Resistance Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Thyroid Abnormalities, ICU Acquired Weakness
Association Between Thyroid Dysfunction and Intensive Care Unit Acquired Weaknesss
Intensive care unit-acquired weakness (ICU-AW) is the most common neuromuscular impairment in critically ill patients. It affects more than 50 % of patients in the intensive care and is related to many problems as difficult…
- Trial name
- NCT04313101
- Testing
- withdrawl of blood samples for thyroid function testing
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Ain Shams University
Intensive Care Unit Acquired Weakness, Critical Care
CYCLE Pilot Randomized Trial
Background: Patients in the intensive care unit (ICU) are the sickest in hospital, and need advanced life-support. Survivors of critical illness are very weak and disabled.
- Conditions
- Intensive Care Unit Acquired Weakness, Critical Care, Mechanical Ventilation, Respiratory Failure
- Trial name
- CYCLE Pilot (NCT02377830)
- Testing
- In-bed cycle ergometer (Restorative Therapies RT300 Supine), Routine physiotherapy
- Where
- 9 sites in United States, Australia and 1 more
- Volunteers
- 113 people
- Sponsor
- McMaster University
Electroacupuncture, Urinary Incontinence
Electroacupuncture Treatment for Urinary Incontinence (UI) in Women
The investigators have developed an investigation comparing electroacupuncture with pelvic floor exercises in female urinary incontinence (UI).
- Conditions
- Electroacupuncture, Urinary Incontinence, Women, Pelvic Floor Muscle Weakness
- Trial name
- ELECAPUN (NCT04842695)
- Testing
- electroacupuncture group
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Knee Osteoarthritis
Hip Abductor Strengthening Exercises in Knee Osteoarthritis
The aim of this randomized controlled trial is to find the effect of hip abductor strengthening exercises on pain, range of motion, functional disability and balance in patient with knee osteoarthritis.
- Trial name
- NCT06845657
- Testing
- Hip Abductor Strengthening Exercises, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Intensive Care Unit Acquired Weakness
Muscle Effects Of Neuromuscular Electrostimulation In Mechanically Ventilated Patients In An Icu
To prevent the development of ICUAW, both early mobilization and neuromuscular electrical stimulation (NMES) have been shown to prevent muscle atrophy in critically ill patients by preserving muscle mass.
- Trial name
- NCT06409611
- Testing
- neuromuscular electrical stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 22 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Muscle Weakness, Sepsis
Evaluating Muscle Weakness Improvement With Lorcaserin in ICU
ICU acquired muscle weakness is a significant problem in patients recovering from critical illness. This trial will evaluate the safety and efficacy of a drug in improving muscle weakness in critically ill patients.
- Trial name
- EMILI (NCT02523690)
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition
Effect of a Home-based Electrical Stimulation on Quadriceps Function After Knee Surgery
The purpose of this study is to determine if a home-based electrical stimulation (ES) program is more effective than the standard of care (SOC) at improving quadriceps function, functional outcomes, patient reported outcomes, and…
- Conditions
- Post-operative Quadriceps Weakness, Post-operative Quadriceps Inhibition, Adherence to Post-operative Treatment, Post-operative Lower Extremity Function
- Trial name
- NCT02058862
- Where
- 2 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Kentucky
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Stroke
At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.
The goal of this clinical trial is to learn if wearable sensor data visualization on smartphones can improve the use of the stroke-affected limb during everyday activities.
- Trial name
- NCT06787729
- Testing
- mHealth
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spaulding Rehabilitation Hospital
Systemic Hypertension, Muscle Weakness
Investigation of Factors Affecting Cardiorespiratory Fitness in Individuals With Systemic Hypertension
The investigators aim to investigate the factors affecting cardiorespiratory fitness in individuals with systemic hypertension.
- Conditions
- Systemic Hypertension, Muscle Weakness, Vascular Stiffness
- Trial name
- NCT04396405
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Diaphragm Dysfunction
Incidence and Impact of ICU-acquired Diaphragm Weakness
ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and…
- Trial name
- PRODIGY (NCT06420999)
- Testing
- Diaphragmatic ultrasound and data collection
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabete Type 2
Vitamin K2 and Muscle Weakness in Type 2 Diabetes
The aim of the current study is to determine the effects of vitamin K2 supplementation on muscle size and function in adults with muscle weakness and type 2 diabetes.
- Trial name
- SARK2 (NCT05375630)
- Testing
- Vitamin K2
- Where
- Kuwait
- Volunteers
- 150 people
- Sponsor
- Dasman Diabetes Institute
COPD, CHF
Heart Failure Worsens Muscle Strength in COPD
The combination of heart failure (HF) and chronic obstructive pulmonary disease (COPD) is highly prevalent, but underdiagnosed and poorly recognized.
- Conditions
- COPD, CHF, Muscle Weakness
- Trial name
- NCT04261452
- Testing
- isokinetic dynamometer, Cardiopulmonary Exercise Test, Functional Capacity Tests
- Volunteers
- 50 people
- Sponsor
- Mayron Faria de Oliveira
Intensive Care Unit Acquired Weakness, Sepsis, Severe
Is NMES Treatment in Sepsis/ Septic Shock Patients Protective in Development of ICU-AW?
Background: Sarcopenia (muscle weakness) characterized by a decrease in muscle mass, strength and performance is a condition that increases with old age.
- Trial name
- NCT04833621
- Testing
- NMES GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Ondokuz Mayıs University
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