Clinical trials: Weakness
Low Back Pain, Mechanical, Pelvic Floor Muscle Weakness
Investigation of Pelvic Floor Muscle Strength in Low Back Pain
To evaluate the effect of pelvic floor muscle strength on women with non-specific low back pain
- Conditions
- Low Back Pain, Mechanical, Pelvic Floor Muscle Weakness, Non-specific Low Back Pain, Disability Physical
- Trial name
- NCT05811572
- Testing
- measurement of pelvic floor muscle with perinometer
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gulhan Yilmaz Gokmen
Multiple Sclerosis, Muscle Weakness
Foot Muscles Training in Sclerosis
The study tries to assess the efficacy of an 8-week IFM training programme on stability in patients diagnosed with Multiple Sclerosis
- Conditions
- Multiple Sclerosis, Muscle Weakness, Training Group, Sensitivity
- Trial name
- NCT06665607
- Testing
- Intrinsic Mucle Training
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Inés Llamas-Ramos
Hospital Mobility, Mobility Limitation
An INtervention TO Improve MOBility of Older Hospitalized Patients
Low mobility during an acute care hospitalization is very frequent, particularly among older patients, and associated with adverse outcomes, such as persistent functional decline, institutionalization and death.
- Conditions
- Hospital Mobility, Mobility Limitation, Life-Space, Functional Status
- Trial name
- INTOMOB (NCT05639231)
- Testing
- INTOMOB intervention
- Where
- 4 sites in Switzerland
- Volunteers
- 383 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
COPD, Inspiratory Muscle Weakness
Effects of Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease (COPD)
The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied.
- Trial name
- IMTCO (NCT01903772)
- Testing
- Inspiratory Muscle Training
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Muscle Weakness
The Effect of Exercise on Muscle, Function and Cost in VA Nursing Home Residents
Veterans are admitted to Veterans Health Administration (VA) Nursing Homes (NH) because impairment in their ability to perform activities of daily living (ADL) overwhelms their support system (family/friends) in the community.
- Trial name
- NCT00105807
- Testing
- participation in low intensity exercise, participation in art and music activities
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs
Muscle Soreness, Muscle Weakness
Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings
The primary purpose of the study is to assess the muscle contractility and sensitivity of lumbar erector spinae, biceps femoris, and gluteus maximus short-term response to Tabata kettlebell swing protocol.
- Conditions
- Muscle Soreness, Muscle Weakness, Muscle Tenderness
- Trial name
- NCT05607212
- Testing
- Kettlebell Swing, Isometric Hold, Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Muscle Weakness Condition, Therapy Effect
Vibrational-proprioceptive Resistance Exercise Training Versus Neuromuscular Electrical Stimulation Training in Elderly People With Muscle Weakness
Study the structural behaviours of weak muscle of elderly and evaluate the efficiency of two different types of training.
- Trial name
- MOBIL (NCT01679977)
- Testing
- Vibrational-proprioceptive Resistance Exercise Training, Neuromuscular Electrical Stimulation Training
- Where
- 2 sites in Austria, Slovakia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation
Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD
PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)
The purpose of this Phase 1/2a trial is to evaluate the safety, tolerability, and preliminary efficacy of PBGENE-DMD in patients with DMD harboring mutations amenable to excision of exons 45-55.
- Trial name
- NCT07429240
- Testing
- PBGENE-DMD (IV)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Precision BioSciences, Inc.
Orthostatic Hypotension, Parkinson's Disease
A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease
This is a study to evaluate the effects of an investigational drug, Droxidopa, in participants with neurogenic orthostatic hypotension (NOH), associated with Parkinson's disease.
- Trial name
- 306A/306B (NCT01176240)
- Testing
- Droxidopa
- Where
- 60 sites in United States
- Volunteers
- 225 people
- Sponsor
- Chelsea Therapeutics
Muscle Weakness | Patient, Intensive Care (ICU) Myopathy
Whole-Body Vibration Versus Neuro Muscular Electrical Stimulation on Patients With ICU Acquired Weakness
Purpose: to investigate the effect of Whole-body vibration versus neuro-muscular electrical stimulation on patients with intensive care-acquired weakness.
- Conditions
- Muscle Weakness | Patient, Intensive Care (ICU) Myopathy, Intensive Care (ICU)
- Trial name
- NCT07336810
- Testing
- whole body VIBRATION Viberation, Neuro muscular electrical stimulation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2
Krill Oil and Muscle Weakness in Type 2 Diabetes
The age-related loss of muscle mass and function, sarcopenia, has several deleterious effects, such as a reduction in the quality of life and an increase in the incidence of falls, often leading to hospitalisation.
- Trial name
- KRIMD (NCT04943523)
- Testing
- Krill Oil, Vegetable Oil
- Where
- Kuwait
- Volunteers
- 150 people
- Sponsor
- Dasman Diabetes Institute
Hypertension
Influence of Respiratory Muscle Training in Elderly Hypertensive Women With Respiratory Muscle Weakness
This study aims to evaluate pulmonary function and respiratory muscle strength in a group of elderly women with hypertension before and after a respiratory muscle training.
- Trial name
- NCT01743183
- Testing
- Threshold
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Sleep, Patient Compliance
The Effect of Ergonomic Sleep Mask Usage on Patients' Sleep Quality and Comfort
In intensive care units, the sleep quality of patients decreases considerably due to reasons such as alarm sounds of some special devices, the number of healthcare professionals working in comparison to other clinics, their…
- Conditions
- Sleep, Patient Compliance, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05297188
- Testing
- ergonomic sleep mask
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Bartın Unıversity
Asthenia, COVID-19
Safety and Efficacy of the Therapy With BRAINMAX® for the Treatment of Patients With Asthenia After COVID-19
This is prospective multicentre comparative randomized double blind placebo controlled study conducted in 6 medical facilities.The objective of the study is to assess the safety and efficacy of the sequential therapy with…
- Trial name
- NCT05689827
- Testing
- Ethyl methyl hydroxypyridine succinate + Meldonium
- Where
- 6 sites in Russia
- Volunteers
- 160 people
- Sponsor
- Promomed, LLC
Movement Disorders
Physiology of Weakness in Movement Disorders
This study will compare electroencephalograph (EEG) recordings in healthy volunteers and in people with movement disorders to examine brain activity associated with the weakness.
- Trial name
- NCT00307346
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Muscle Weakness, XLH
Muscle Abnormalities in Children With XLH
XLH rickets is a rare disease with muscle weakness. Fat parameters such as IMAT and intraMAT could be increased in this disease.
- Trial name
- MDmuscleXLH (NCT05312086)
- Testing
- MRI
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Surgery, Postoperative Period
Efficacy of Triburter on Respiratory Muscle Function in Patients After CABG in Cardiac Rehabilitation Phase II
Post-surgery patients have muscle impairments, especially in the respiratory muscles, because the anesthesia, surgical incision, mechanical ventilation, pain, and prolonged postures, affect the mechanical condition of respiratory…
- Conditions
- Thoracic Surgery, Postoperative Period, Weakness, Muscle
- Trial name
- NCT05496049
- Testing
- Triburter, Incentive spirometry
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Breast Cancer
Respiratory Muscle Strength Training to Prevent Respiratory Muscle Weakness in Adults Newly Diagnosed With Breast Cancer
The goal of this clinical trial is to learn if respiratory muscle strength training can prevent respiratory muscle weakness in adults who are newly diagnosed with breast cancer and are planning to have surgery.
- Trial name
- NCT07229378
- Testing
- Respiratory muscle strength training, Guided Imagery Exercises
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Muscle Weakness, Weaning Failure
Abdominal Muscle Thickness in Mechanically Ventilated Patients
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated…
- Trial name
- NCT03567564
- Testing
- Abdominal muscles ultrasound
- Where
- 2 sites in Canada, Italy
- Volunteers
- 35 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB)
Comparing CPAP and BiPAP for Sleep-Disordered Breathing in People with Cervical Spinal Cord Injuries
Sleep-disordered breathing (SDB) is common in individuals with cervical spinal cord injuries, with studies suggesting prevalence rates ranging from 27% to 62%.
- Conditions
- Spinal Cord Injuries (SCI), Sleep Disordered Breathing (SDB), Sleep Apnea, Cervical Spinal Cord Injruy
- Trial name
- NCT06818604
- Testing
- CPAP, BiPAP
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
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