Clinical trials: Weakness
Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients
Effect of Respiratory Trainer on Cardiopulmonary Functions in Patients with Upper Cross Syndrome Post-Cardiac Surgery
The purpose of this study is to investigate if there is any effect of the respiratory training on cardiopulmonary functions in patients with upper cross syndrome post-cardiac surgery.
- Conditions
- Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients, Upper Cross Syndrome, Respiratory Muscle Weakness
- Trial name
- NCT06673953
- Testing
- Respiratory Muscle Training by (The Breather), Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
IBM, Inclusion Body Myositis
Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis
This study will evaluate whether neuromuscular ultrasound and MRI can be used as imaging markers of bulbar involvement and swallowing dysfunction in individuals with inclusion body myositis (IBM).
- Conditions
- IBM, Inclusion Body Myositis, Myopathy, Myositis
- Trial name
- NCT07823101
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Muscle Weakness, Rehabilitation
Efficacy of Different Treatments for the Intensive Care Unit Acquired Weakness
Experimental study that has how to compare the efficacy between conventional rehabilitation, transcutaneous electrostimulation or early mobilization to reduce the time needed to reverse the muscle weakness evaluated by the muscle…
- Trial name
- NCT04613908
- Testing
- neuro muscular electro stimulation, Early Mobilization protocol, standard care or usual rehabilitation
- Volunteers
- 18 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Muscle Weakness
Effect of Supplementary Dietary Protein (21g Per Day) on Lean Mass and Strength in Sedentary, Adult Vegetarians
It is possible that the lower protein intake in vegetarians and vegans may relate to a decrease in grip strength. Furthermore, there is limited research examining the effects of plant-based protein intake on strength and LBM…
- Trial name
- MungBean (NCT04076982)
- Testing
- mung bean protein, control biscuit
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Congenital Heart Disease, ICU Acquired Weakness
Muscle Catabolism and Outcomes in Children Following Cardiac Surgery
Background \& Significance. Children with congenital heart disease (CHD) have experienced improved postoperative survival shifting the focus away from minimizing mortality to curtailing morbidities.
- Conditions
- Congenital Heart Disease, ICU Acquired Weakness, Catabolic State
- Trial name
- MOCHI (NCT04998643)
- Testing
- Muscle ultrasound to estimate lean body mass
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Boston Children's Hospital
Parkinson Disease, Surgery
The Effects Of DBS Of Subthalamıc Nucleus On Functionality In Patıents With Parkinson's Disease: Short-Term Results
Parkinson's disease is a progressive chronic neurodegenerative disease. In cases where drug treatment is insufficient and drug use is not possible due to drug side effects, highly effective and low-risk surgical treatment options…
- Conditions
- Parkinson Disease, Surgery, Respiration; Decreased, Muscle Weakness
- Trial name
- NCT03797976
- Testing
- MIP and MEP
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Mustafa Kemal University
Subjects With Deep Cervical Muscle Strength Deficit
Effectiveness of Two Exercise Programs on the Neck.
The purpose of this study is to evaluate the clinical results in lower cervical range of motion, size deep muscles, endurance, craniovertebral angle and cervical propioception by a training protocol with the new device for…
- Trial name
- NCT05331482
- Testing
- Training protocol with the cervical device for treatment (CDAT)., Conventional training protocol
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Neuromuscular Diseases, Central Hypoventilation
'Fitness To Fly' Tests In Children With Type II Respiratory Failure
The conventional hypoxic challenge test might not predict 'fitness-to-fly' equally well in all patients. Patients at risk of hypercapnia with supplemental oxygen are not well studied.
- Trial name
- NCT03824223
- Testing
- Hypoxic challenge test
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Sepsis, Critical Illness
MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength.
- Conditions
- Sepsis, Critical Illness, ICU-acquired Muscle Weakness, ICU-acquired Weakness
- Trial name
- ICUAW (NCT07362862)
- Testing
- Electrical Muscle Stimulation System
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Health Discovery Labs
Anterior Cruciate Ligament Injuries, Atrophy
Effect of Blood Flow Restriction Training on Patient With Anterior Cruciate Ligament Reconstruction
This study investigates the effects of plyometric training with blood flow restriction on muscular strength, quadriceps thickness and knee joint function in patients with muscle weakness and atrophy (quadriceps muscle and…
- Conditions
- Anterior Cruciate Ligament Injuries, Atrophy, Muscle Weakness
- Trial name
- NCT04284748
- Testing
- Plyometric exercise with blood flow restriction, Plyometric exercise, Routine physiotherapy program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Low Back Pain, Hamstring Pulled
Immediate Effect of Mulligan Two Leg Rotation and Bent Leg Raise Techniques on Hamstring Tightness
The aim of this study is to compare the immediate effect of mulligan's two leg rotation and bent leg raise for hamstring tightness, core muscle weakness in chronic low back pain, lumbar Range of motion.
- Trial name
- NCT04747925
- Testing
- Mulligan two leg rotation core muscle strengthning exercises, mulligan bent leg raise technique, core muscle strengthning exercises
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Velopharyngeal Insufficiency, Articulation Disorders
Efficacy of an Arabic Articulatory Error Remediation Software Program in Patients With Velopharyngeal Valve Dysfunction:
To develop a remediation software program that is specific for correcting speech errors in patients with velopharyngeal dysfunction in the Arabic language and test its efficacy, on one group comparing pre and post results
- Conditions
- Velopharyngeal Insufficiency, Articulation Disorders, Hypernasality Syndrome Due to Velopharyngeal Weakness
- Trial name
- NCT04392817
- Testing
- Arabic Articulatory Error Remediation software program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alaa Mamdouh
Muscle Weakness, Balance Disorders
Different Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Knee Osteoarthritis
The aim of this study is to investigate the effects of 6-week physiotherapy and rehabilitation programs involving different 'Proprioceptive Neuromuscular Facilitation' (PNF) techniques in patients with knee osteoarthritis on…
- Conditions
- Muscle Weakness, Balance Disorders, Knee Pain, Knee Osteoarthritis
- Trial name
- NCT03615521
- Testing
- Hotpack, Ultrasound, Combine Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Karamanoğlu Mehmetbey University
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Muscle Atrophy, Muscle Weakness
Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Post-intensive care syndrome (PICS) encompasses persistent physical, cognitive, and psychiatric symptoms following ICU discharge, commonly triggered by serious conditions such as respiratory failure, sepsis, and mechanical…
- Conditions
- Muscle Atrophy, Muscle Weakness, Blood Flow
- Trial name
- NCT06238609
- Testing
- Intervention Group, Control Group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bijan Najafi, PhD
Cystic Fibrosis
1STST and Muscle Weakness in CF Patients
The investigators know that peripheral muscle weakness and exercise intolerance are prevalent (56%) in cystic fibrosis (Trooster et al, 2009). Physical inactivity is likely to be an important underlying factor.
- Trial name
- NCT03117764
- Testing
- Microfet Dynamometer, 1 minute sit to stand test, Accelerometer
- Where
- Belgium
- Volunteers
- 81 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Myotonic Dystrophy Type-1, Myotonic Dystrophy Type-2
Assessing Clinical Endpoints and Biomarkers in Myotonic Dystrophy Type-1 and Type 2 (ASCEND-DM)
Background: Myotonic dystrophy is a long-term genetic disorder that affects muscle function. Symptoms include gradually worsening muscle loss and weakness. Muscles often contract and cannot relax.
- Trial name
- NCT03867435
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Breast Cancer, Quality of Life
Pilates and Dance to Breast Cancer Patients Undergoing Treatment
Breast cancer is one of the most common types of cancer in Brazil, and its treatment, namely surgery, chemotherapy, radiotherapy or hormone therapy, has consequences and side effects that significantly affect the quality of life…
- Conditions
- Breast Cancer, Quality of Life, Lymphedema, Fatigue
- Trial name
- NCT03194997
- Testing
- Dance, Pilates
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Laboratório de Pesquisa em Lazer e Atividade Física
Diastasis Recti
Effects of AHEs on DrA in Postpartum Women
This study is aimed to determine the effects of Abdominal Hypopressive exercises on IRD, Lumbopelvic pain, Body Image and abdominal muscle function in postpartum women.
- Trial name
- NCT05931159
- Testing
- Abdominal Hypopressive Training, Conventional Physical therapy for DrA
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Critical Illness Myopathy
NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness
The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illness myopathy (CIM).
- Trial name
- PT-NLRP3-CIM (NCT07017517)
- Testing
- Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
- Where
- 3 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
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