Clinical trials: Weakness
Intermittent Exotropia
Early Results of Slanted Recession of the Lateral Rectus Muscle for Intermittent Exotropia With Convergence Weakness
This study was conducted to evaluate results of slanted recession of the lateral rectus muscle for intermittent exotropia with convergence weakness
- Trial name
- NCT02131792
- Testing
- Slanted recession of the lateral rectus muscle
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Kyungpook National University Hospital
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Muscle Weakness, Quadriceps Muscle Atrophy
NM Balance Regulation With ULLS and Loss of Sleep
The goal of this trial is to learn about how restricted sleep and not bearing weight on the leg affects muscle strength and posture control.
- Conditions
- Muscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
- Trial name
- NCT05956964
- Testing
- Sleep Restriction, Sleep Adequate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lance Bollinger
ICU Acquired Weakness
ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.
This study is testing whether a non-invasive nerve monitoring device (TetraGraph) can accurately detect early signs of ICU-acquired weakness by comparing readings from the device with standard nerve conduction/EMG tests done by a…
- Trial name
- ICU CONNECT (NCT07699562)
- Testing
- TetraGraph, Electromyography, Nerve conduction studies
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Neuromuscular Electrical Stimulation, ICU Acquired Muscle Weakness
Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients
Intensive care unit-acquired muscle weakness (ICUAMW) is a common problem following an ICU admission and is associated with prolonged hospitalization, delayed weaning and increased mortality.
- Trial name
- NCT05465291
- Testing
- Exercise group, Neuromuscular Electrical Muscle Stimulation group, Neuromuscular Electrical Muscle Stimulation and Exercise group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour University
Heart Failure
The Effects of the Inspiratory Muscle Plus Aerobic Training Compare to Aerobic Training Alone in Heart Failure Patients.
This study aims to compare effects of inspiratory muscle training added by aerobic training to aerobic training alone in heart failure patients with inspiratory muscle weakness.
- Trial name
- NCT00634296
- Testing
- Inspiratory muscle added by aerobic to aerobic alone
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Myeloid Leukemia (AML)
Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML
This trial will evaluate whether luveltamab tazevibulin is well tolerated and active against a rare form of AML carrying a particular genetic abnormality called CBFA2T3::GLIS2 that arises in infants and children.
- Trial name
- NCT06679582
- Testing
- Luveltamab tazevibulin
- Where
- 36 sites in United States, Austria and 7 more
- Volunteers
- 1 people
- Sponsor
- Sutro Biopharma, Inc.
Inclusion Body Myositis (IBM), Motor Neuron Disease, Amyotrophic Lateral Sclerosis
The Aim of the Study is to Characterize Patients Exhibiting Muscular Atrophy and Weakness Who Require a Muscle Biopsy for Diagnosis (IBM vs Atypical MND), Through an Innovative Technique Which Enables the Evaluation of the Neuromuscular Junction Involvement in Each Condition
The aim of the study is to characterize 30 patients exhibiting muscular atrophy and weakness who require a muscle biopsy for diagnosis (suspected inclusion body myopathy vs atypical motor neuron disease), through an innovative…
- Trial name
- TDP-signatures (NCT07796776)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele
Critical Illness, Muscle Weakness
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
The rapid decline of muscle mass and function in mechanically ventilated critically ill patients is associated with prolonged length of mechanical ventilation, prolonged intensive care (ICU) and hospital stay, increased ICU and…
- Trial name
- HMB-ICU-CH (NCT03628365)
- Testing
- HMB (beta-hydroxy beta-methylbutyrate)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Mette M Berger
Respiratory Disease, Muscle Weakness
Respiratory Muscle Training in Acquired Brain Injury Patients.
Background: Respiratory health problems are one of the main causes of morbidity and mortality in adult people with acquired brain injury (ABI).
- Conditions
- Respiratory Disease, Muscle Weakness, Acquired Brain Injury, Older People--Abuse of
- Trial name
- NCT06070831
- Testing
- Inspiratory muscle training, Expiratory muscle training
- Volunteers
- 26 people
- Sponsor
- University of Salamanca
Knee Osteoarthritis, Muscle Weakness
Knee Pressure Stimuli on Quadriceps Strength in Knee Osteoarthritis
The study aims at investigating the effects of a periarticular knee pressure stimulation on quadriceps strength and neuromuscular activity in subjects with knee ostearthritis.
- Trial name
- NCT05826236
- Testing
- Periarticular compression
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
Shoulder Pain, Muscle Weakness
Effect of Kinesio Taping on Muscle Strength in Lower Trapezius
The purpose of this project is to investigate the effect of Kinesio tape on muscle strength of the lower trapezius in people with shoulder symptoms and decreased muscle strength in the lower trapezius - a randomized controlled…
- Trial name
- NCT02290730
- Testing
- Kinesio tape
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- Norwegian School of Sport Sciences
Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness
Influence of Physical Therapy for Foot and Ankle in the Gait of Individuals With Diabetic Neuropathy
The hypothesis is that a physical therapy intervention for foot and ankle of diabetic neuropathic individuals would affect positively the way they walk, lowering the harmful forces that these segments receive, that are associated…
- Conditions
- Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness, Foot and Ankle Range of Movement Restriction
- Trial name
- NCT01207284
- Testing
- Physical Therapy
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo General Hospital
Myasthenia Gravis
The Adapting Disease Specific Outcome Measures Pilot Trial for Telehealth in Myasthenia Gravis
The goal of this pilot study is to determine the reliability of myasthenia gravis (MG) specific outcome measures obtained during virtual encounters with patients with myasthenia gravis.
- Trial name
- ADAPT-teleMG (NCT05917184)
- Testing
- Telehealth
- Where
- 5 sites in United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Coronavirus Infection, Sars-CoV2
Outcomes in Hospitalized Older Patients With COVID-19
In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly…
- Conditions
- Coronavirus Infection, Sars-CoV2, Elderly Infection, Old Age; Debility
- Trial name
- NCT04385212
- Where
- Switzerland
- Volunteers
- 230 people
- Sponsor
- University Hospital, Geneva
Muscle Performance, Sarcopenic Obesity
Safety and Efficacy of IMM01-STEM Against Placebo on Muscle Performance in Seniors With Obesity and Muscle Weakness
Placebo controlled study for safety and efficacy of IMM01-STEM on muscle performance in seniors with obesity and muscle weakness
- Trial name
- NCT06600581
- Testing
- IMM01-STEM
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Immunis, Inc.
Weakness, Atrophy
Evaluation of Thermal-Aided Muscle Stimulation
An investigation into the relative effectiveness of thermal-aided muscle stimulation vs. body temperature muscle stimulation for eliciting muscle contraction in the quadriceps
- Trial name
- NCT01911312
- Testing
- Thermal-aided muscle stimulation, Body Temperature Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Niveus Medical, Inc.
Healthy
Structure and Function of the Human Tongue
This study will use magnetic resonance imaging (MRI) and ultrasound to examine changes in tongue volume and blood circulation during tongue exercises that require the use of different tongue muscle movements and contractions.
- Trial name
- NCT00007137
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Urinary Dysfunction, Vaginal Prolapse
Effects of Kegel Ball and Pelvic Floor Exercises on Sexual Function, Unrınary Incontinence and Quality of Life in Women
Urinary incontinence and sexual dysfunction are common conditions that can significantly impact quality of life. Although surgical and medical treatments are available, many individuals seek non-invasive alternatives.
- Conditions
- Urinary Dysfunction, Vaginal Prolapse, Sexual Function Scores, Kegel Exercises
- Trial name
- NCT07048145
- Testing
- Vaginal Kegel Exercise Ball, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- sahra sultan kara
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