Clinical trials: Weaning Mechanical Ventilation
Weaning From Mechanical Ventilation
Diaphragmatic Tissue Doppler During Weaning From Mechanical Ventilation
Weaning from mechanical ventilation is a critical issue and the diaphragmatic disfunction has been demonstrated to play an important role in extubation failure.
- Trial name
- TDD-wean (NCT03962322)
- Testing
- Weaning TDI
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Weaning From Mechanical Ventilation
Mechanical Ventilation- Weaning and Thoracic Impedance Tomography
The aim of this multicenter, randomized controlled trial is to evaluate the weaning time from mechanical ventilation comparing non-variable PSV, variable PSV, and Smart CareTM.
- Trial name
- NCT03018483
- Testing
- Variable PSV, Conventional PSV, Automated PSV
- Where
- Italy
- Volunteers
- 342 people
- Sponsor
- Federico II University
Mechanical Ventilation, Single-lung Ventilation
Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time
The results of this study will help to define the capability and reliability of PulmoVista 500 to detect changes in both global and regional ventilation.
- Conditions
- Mechanical Ventilation, Single-lung Ventilation, ARDS, ALI - Acute Lung Injury
- Trial name
- NCT03076983
- Testing
- Lung Monitoring with EIT device (PulmoVista 500)
- Where
- 3 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Drägerwerk AG & Co. KGaA
Muscle Weakness Condition, Mechanical Ventilation Complication
Hand Grip Strength and Medical Research Council Scale as Predictors of Weaning Failure
The handgrip strength (HGS) will be measured with a digital dynamometer. Three measurements will be taken, whose average of the three measurements will be collected.
- Conditions
- Muscle Weakness Condition, Mechanical Ventilation Complication, Weaning Failure
- Trial name
- NCT03991702
- Testing
- diagnostic test
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mechanical Ventilation, Mechanical Ventilator Weaning
Diaphragmatic Ultrasound Associated With RSBI Predict Weaning Issue: the Rapid Shallow Diaphragmatic Index (RSDI)
The Rapid Shallow Breathing Index (RSBI) is the ratio between respiratory rate (RR) and tidal volume (VT). It is routinely used to predict mechanical ventilation weaning outcome in ICU patients.
- Conditions
- Mechanical Ventilation, Mechanical Ventilator Weaning, Extubation, Diaphragm Ultrasound
- Trial name
- CODEX (NCT03479047)
- Testing
- assess diaphragmatic displacement (DD) using ultrasonography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Weaning Failure, Mechanical Ventilation Complication
Lung Impedetiometric Modification in SBT and Extubation Failure
Weaning is the entire process aimed at liberating patients from mechanical ventilation and endotracheal intubation. Weaning should be considered as early as possible in order to reduce the time spent in invasive mechanical…
- Trial name
- CPAP2-EIT (NCT03894332)
- Testing
- Electrical Impedance Tomography (EIT)
- Volunteers
- 80 people
- Sponsor
- University Magna Graecia
Adults With Cardiopulmonary Disease at Risk of Prolonged Weaning From Mechanical Ventilation
Neurally Adjusted Ventilatory Assist in Adults at Risk of Delayed Weaning From Mechanical Ventilation
Many patients admitted to intensive care have heart or lung problems. Patients with these conditions often require longer durations of support from breathing machines.
- Trial name
- RESTUS (NCT01826890)
- Testing
- NAVA Technology
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- King's College Hospital NHS Trust
Sleep Quality, Weaning of Mechanical Ventilation
Impact of Sleep Quality on Respiratory Function and Weaning of Mechanical Ventilation
The aim of the study is to evaluate the impact of sleep quality on the length of mechanical ventilation weaning, in intensive care unit patients
- Trial name
- WEAN SLEEP 1 (NCT02920281)
- Testing
- Polysomnography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Weaning of Mechanical Ventilation, Chronic Obstructive Pulmonary Disease
Spontaneous Breathing Trials Using Pressure-Support or T-Tube in Chronic Obstructive Pulmonary Disease Patients Weaning Mechanical Ventilation
Weaning of mechanical ventilation (MV) is an essential part in management of patients with Chronic Obstructive Pulmonary Disease (COPD) when critically ill. The best strategy to be used has not been established.
- Trial name
- NCT01464567
- Testing
- "T" Tube Spontaneous Breathing Trial, Pressure Support Ventilation
- Where
- 2 sites in Brazil
- Volunteers
- 190 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Weaning From Mechanical Ventilation
Comparison of Weaning on Pressure Support vs. Proportional Assist Ventilation: A Pilot Study
The study hypothesis is that reducing patient-ventilator asynchrony will reduce time required to wean from mechanical ventilation.
- Trial name
- NCT01666054
- Testing
- PSV, PAV
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Critical Care, Weaning From Mechanical Ventilation
Lung Aeration During WEANing From Mechanical Ventilation Determined by Electrical Impedance Tomography and Lung Ultrasound
Evaluation of lung aeration during weaning from mechanical ventilation determined by electrical impedance tomography and lung ultrasound
- Conditions
- Critical Care, Weaning From Mechanical Ventilation, Electrical Impedance Tomography, End Expiratory Lung Volume
- Trial name
- IWEAN (NCT02361021)
- Testing
- - Weaning from mechanical ventilation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intensive Care Medicine, Mechanical Ventilation
The Classification of Difficult Weaning and the Predictive Value of Relative Factors for Difficult Weaning
To evaluate the distribution of different types of difficult weaning and the predictive value of weaning relative factors.
- Conditions
- Intensive Care Medicine, Mechanical Ventilation, Weaning
- Trial name
- NCT02487927
- Testing
- weaning
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Jianfeng Xie
Mechanical Ventilation, Weaning
Automated Ventilator Controlled Weaning vs Daily Spontaneous Breathing Trial in Difficult to Wean ICU Patients
This study will compare Drager Smart Care (SC), a commercially available automated ventilator controlled weaning mode to the current daily spontaneous breathing trial (SBT) weaning protocol.
- Trial name
- NCT00813839
- Testing
- daily weaning trails
- Where
- United States
- Sponsor
- University of California, San Francisco
Weaning From Mechanical Ventilation
Post Extubation Chest Physiotherapy in ICU
The purpose of this study is to examine the efficacy of chest physiotheray treatment in preventing pulmonary complications and weaning faliure, in extubated critically ill patients.
- Trial name
- NCT01967108
- Testing
- chest physiotherapy
- Where
- Israel
- Volunteers
- 65 people
- Sponsor
- Rambam Health Care Campus
Functional Test, COPD, Neuromuscular Disorders, Mechanical Ventilation, Weaning, Disability
MIND Score for Prolonged Mechanical Ventilation
It was decided to develop a comprehensive disability score specifically designed for patients receiving prolonged mechanical ventilation (PMV); the collection of information included in the score should not impose any further…
- Trial name
- MIND (NCT02255058)
- Testing
- No intervention
- Where
- 5 sites in Argentina, Colombia and 1 more
- Volunteers
- 129 people
- Sponsor
- Linde AG
Critical Illness, Mechanical Ventilation
"NAVA-PAV" Study: a Cross-over Comparative Study of 2 Advanced Modes
Neurally adjusted ventilatory assist (NAVA) and Proportional Assist Ventilatory Plus (PAV +) are new modes of mechanical ventilation that delivers ventilatory assist in proportion to the electrical activity of the diaphragm for…
- Conditions
- Critical Illness, Mechanical Ventilation, Intensive Care, Ventilation Weaning
- Trial name
- NCT01607723
- Testing
- NAVA ventilatory mode, PAV+ ventilatory mode
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Montpellier
Critical Care, Weaning of Mechanical Ventilation
A Cardiac Ultrasound Evaluation of Two Types of Weaning Trials of Mechanical Ventilation for a First Weaning Trial
Comparing the hemodynamic and cardiac effects of two types of weaning trials of mechanical ventilation in ICU patients of two French ICU.
- Conditions
- Critical Care, Weaning of Mechanical Ventilation, Trans-thoracic Echocardiography, Mitral Doppler
- Trial name
- CARWEAN (NCT02138903)
- Testing
- trans thoracic echocardiography
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Mechanical Ventilation Weaning
New Integrated Weaning Indexes
The purpose of this study is to determine whether introducing the new weaning indexes can predict better than traditional ones?
- Trial name
- NIWIs (NCT01779297)
- Where
- Iran
- Volunteers
- 1,175 people
- Sponsor
- Baqiyatallah Medical Sciences University
Traumatic Brain Injury, Weaning Failure
Study of Variables Related to the Discontinuation of Mechanical Ventilation in Patients With Head Injury
The purpose of this study is to evaluate physiological variables to the decision about the appropriate time to discontinuation of mechanical ventilation in patients with traumatic brain injury.
- Conditions
- Traumatic Brain Injury, Weaning Failure, Mechanical Ventilation Complication
- Trial name
- INDEXTBI (NCT01713010)
- Testing
- Predictive indexes of weaning from mechanical ventilation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Uberlandia
Mechanical Ventilation Weaning Phase in Children
Safety and Feasibility Study of a Mechanical Ventilation Computerized Protocol: Intellivent
The present protocol will demonstrate the safety, feasibility and efficacy of a newly computerized protocol integrated into a ventilator: S1 ventilator (Hamilton Medical).
- Trial name
- CloserPed (NCT01095406)
- Testing
- S1 ventilation
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- St. Justine's Hospital