Clinical trials: Weight Change, Body
Obesity and Cardiovascular Risk, Insulin Resistance
Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
Obesity is a chronic disease of global public health concern, contributing to cardiovascular disease, type 2 diabetes and certain cancers.
- Conditions
- Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
- Trial name
- MOWRI (NCT07297290)
- Testing
- Metformin
- Where
- 2 sites in Nigeria
- Volunteers
- 220 people
- Sponsor
- University Of Nigeria Teaching Hospital
Obesity
Parents As The Agent Of Change For Childhood Obesity (PAAC)
The objective of this study is to test and evaluate the effectiveness of a parent-only treatment for childhood obesity. This study provides state-of-the-art treatment for childhood obesity.
- Trial name
- PAAC (NCT01066910)
- Testing
- Behavioral treatment for childhood obesity
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Cachexia-Anorexia Syndrome, Cachexia; Cancer
A Phase II Clinical Study Evaluating the Efficacy and Safety of SXRN Injection in Patients With Cancer Cachexia
This is a multicenter, randomized, double-blind, placebo-controlled, dose-finding Phase II clinical study to evaluate the efficacy and safety of SXRN injection in adult patients with cancer-associated anorexia-cachexia.
- Trial name
- NCT07890324
- Testing
- SXRN Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jiangsu Guiqiong Pharmaceutical Co., Ltd.
Obesity
Reducing Obesity Using Social Ties Program
This trial aims to test the feasibility and acceptability of addressing interpersonal barriers to weight-related behavior change.
- Trial name
- ROBUST (NCT06335810)
- Testing
- Social Network Intervention, Individual Lifestyle Intervention, Social Network Member
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Weill Medical College of Cornell University
Overweight and Obesity, Body Weight Changes
FatMax Training on Metabolic and Epigenetic Parameters
Exercise is an essential pillar for the health of all individuals, as it contributes to physical, mental, and emotional well-being.
- Trial name
- NCT06553482
- Testing
- FatMAx training intervention, FatMax and physical endurance exercise intervention, Control
- Where
- Mexico
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Obesity & Overweight
Scannographic Predictive Factors of Change of Strategy During Metabolic Bariatric Surgery
Background: Laparoscopic Roux-en-Y Gastric By-pass (LRYGB) is not always feasible due to intraoperative difficulties, necessitating a change during surgical procedure.
- Trial name
- SCANOBE (NCT07296224)
- Where
- France
- Volunteers
- 288 people
- Sponsor
- Central Hospital, Nancy, France
Pregnancy, Weight Gain
Effectiveness of Video Messaging About Diet, Exercise and Weight Gain in Pregnancy in Regional and National Samples
The primary purpose of this study is to assess the responses of pregnant women and their social network to six videos about health in pregnancy.
- Trial name
- NCT02490579
- Testing
- Responses to Brief Video Messages (Facebook), Response to Brief Video Messages (Clinic), Response to Brief Video Messages (Social Network)
- Where
- United States
- Volunteers
- 1,670 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Overweight and Obesity
Predictors of Lorcaserin-Induced Weight Loss
This two-phase study aims to explore ways to predict who will respond well to the weight loss drug lorcaserin and to understand the mechanisms that develop which limit drug efficacy.
- Trial name
- NCT03353220
- Testing
- Belviq
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infections, HIV Wasting Syndrome
A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome
To evaluate the safety, antiviral and anti-TNF-alpha activity, and preliminary efficacy of thalidomide in reducing weight loss in patients with HIV wasting syndrome.
- Trial name
- NCT00002127
- Testing
- Thalidomide
- Where
- 13 sites in United States
- Volunteers
- 75 people
- Sponsor
- Celgene Corporation
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Protein-Energy Malnutrition, Anorexia
Energy Dense Formula to People Living in Old Peoples Home
Dietary intake in frail elderly is often lower than estimated needs due to the combined effects of the anorexia of ageing, frailty and the presence of acute and chronic disease.
- Conditions
- Protein-Energy Malnutrition, Anorexia, Weight Change
- Trial name
- NCT01259999
- Testing
- Calogen extra strawberry
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Metabolic Syndrome, Obesity & Overweight
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
We investigate the role of empagliflozin in the treatment of obesity in PLWH.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07336797
- Testing
- Empagliflozin (oral)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Abdelrahman Mahmoud
Obesity
SMART: A Social and Mobile Weight Control Program for Young Adults
The Social/Mobile Approach to Reduce Weight (SMART) study is a 24-month randomized control trial designed to evaluate the hypothesis that weight status at 24 months will be significantly better for the SMART intervention…
- Trial name
- SMART (NCT01200459)
- Testing
- Social/mobile weight loss promotion intervention.
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Body Weight Changes
Infant Peer Interaction Study by Examining the Effect of a 6-week Music Enhancement Program
The overall purpose of this study is to better understand food reinforcement in infants. The results of this study should help to further our understanding of how individuals relate to food and how an enriched environment can…
- Trial name
- NCT04289168
- Testing
- Music
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Obesity & Overweight, Older Women
Effects of Adapted Taekwondo Versus Conventional Training on Anthropometric Variables and Physical Function in Older Women With Abdominal Obesity
Therefore, this study aimed to analyze the effects of TKD on anthropometric and physical function parameters in older women with abdominal obesity, compared with conventional exercise interventions such as MCT, and WE.
- Trial name
- RCT (NCT07705750)
- Testing
- taekwondo training, multicomponent training, walking exercise
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Obesity
Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program
The primary aim of this study is to evaluate the extent to which an exercise intervention timed after diet-induced weight loss (rather than initiated at the same time) improves exercise adherence and long-term weight loss.
- Trial name
- NCT01985568
- Testing
- Sequential BT, Standard BT
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
Reduction of Emotional Eating After a Behavior Change Program in Obesity
Recent studies show that overweight people have a greater sensitivity to the rewarding aspect of food due to the disturbance of the dopaminergic system.
- Trial name
- NCT01997697
- Testing
- behavior change program
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Montpellier
Type 2 Diabetes, Overweight
Lifestyle Intervention for Treatment of Diabetes
This study is evaluating two approaches to improving the control blood sugar, and other risk factors for heart disease in overweight and obese adults with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Obesity
- Trial name
- LIFTDiabetes (NCT01806727)
- Testing
- Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Wake Forest University
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital