Clinical trials: Weight Change
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Hypertension
Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health
This study will examine the effects of a low carbohydrate diet versus a high carbohydrate diet on weight loss.
- Trial name
- NCT00200720
- Testing
- Atkins diet (low carbohydrate diet), DASH diet (high carbohydrate diet)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Kaiser Permanente
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Neonatal Abstinence Syndrome
RCT of High- vs. Standard-Calorie Formula for Methadone-Exposed Infants
Neonatal abstinence syndrome (NAS) symptoms contribute to poor infant weight gain. Early caloric enhancement for infants exposed to methadone is inexpensive, readily available, easy to implement and could improve early outcomes…
- Trial name
- NCT02178189
- Testing
- High Calorie Infant formula, Standard Calorie Infant Formula
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Pittsburgh
Overweight and Obesity, Weight Loss
microRNA Testing for Identification of Personalized Weight Management
Certain blood markers are related to one's ability to successfully lose weight by diet and exercise. Currently, the laboratory tests used to measure these blood markers are expensive and time-consuming.
- Trial name
- NCT04217850
- Testing
- 250 kcal Dietary Energy Restriction, Aerobic Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Obesity
Multi-Center Pre-Bariatric Weight Loss Study
The purpose of the study is to evaluate the safety and efficacy of the GI Sleeve in patients who require weight loss prior to their Bariatric surgery.
- Trial name
- NCT00469391
- Testing
- GI Sleeve Implantable weight loss device (EndoBarrier)
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Morphic Medical Inc.
Esophageal Cancer, Weight Gain
Resection of the Esophagus and Subsequent Weight Loss
The investigators aim to ascertain how food reward signals and eating behaviour relates to the gut-brain pathway in weight-losing patients after curative surgery for oesophageal cancer, and how this pathway responds to clinical…
- Conditions
- Esophageal Cancer, Weight Gain, Eating Behavior, Food Reward
- Trial name
- REWARD (NCT03377660)
- Testing
- Clinical treatment
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Functional Dyspepsia
Mirtazapine Versus Placebo in Functional Dyspepsia
Double-blind randomized controlled trials of 8 weeks mirtazapine 15 mg daily or placebo, followed by 8 weeks of open-label mirtazapine 15 mg daily
- Trial name
- NCT01240096
- Testing
- Mirtazapine
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obese or Overweight Healthy Volunteers
Clinical Study to Assess the Safety and Efficacy of ACV Moringa Effervescent Tablet Intake on Weight Management in Overweight and Class I Obese Study Participants
A Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Single-Centre, Clinical Study to Evaluate the Safety and Efficacy of Intake of ACV Moringa on the Degree of Weight Change in Overweight and Class I Obese Study Participants
- Trial name
- NCT07098624
- Testing
- ACV Moringa Effervescent Tablets 4.3 g
- Volunteers
- 66 people
- Sponsor
- NovoBliss Research Pvt Ltd
Carotid Endarterectomy, Percutaneous Transluminal Angioplasty
Study of Blood Flow Changes and Microemboli During Carotid Surgery
The purpose of this study is to determine the clinical and radiologic implications of the intraoperative microemboli during carotid revascularization.
- Conditions
- Carotid Endarterectomy, Percutaneous Transluminal Angioplasty, Cognitive Aspects, Diffusion Weighted MRI
- Trial name
- NCT01343615
- Testing
- carotid stenting, carotid endarterectomy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Campinas, Brazil
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity, Weight Loss
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
The purpose of this registry study is to collect data through medical chart review and in patient visits on the efficacy and safety of various Endoscopic Bariatric therapies (EBTs).
- Conditions
- Obesity, Weight Loss, Gastro Esophageal Reflux, Bariatric Surgery Candidate
- Trial name
- EBT (NCT04494048)
- Testing
- Endoscopic Bariatric Therapies
- Where
- United States
- Volunteers
- 9,999 people
- Sponsor
- Weill Medical College of Cornell University
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Obesity, Bariatric Surgery Candidate
Efficacy of a Mobile Application and Semi-attendance Program in Bariatric Surgery
BACKGROUND: Applications for mobile devices in patients with obesity offer a great opportunity to improve the quality of care and the monitoring of patients in bariatric surgery programs.
- Trial name
- NCT06163235
- Testing
- Obemar platform
- Volunteers
- 72 people
- Sponsor
- Parc de Salut Mar
Cachexia
Single and Multiple Ascending Dose Study of NGM120 in Healthy Adult Subjects
The purpose is to evaluate the safety, tolerability, and PK of NGM120 in healthy adult subjects
- Trial name
- NCT03392116
- Testing
- NGM120
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Morbid Obesity, Obesity
Optic Nerve Sheath Diameter Changes During Bariatric Surgery
This prospective clinical study aimed to evaluate the effects of pneumoperitoneum and patient positioning on intracranial pressure in patients undergoing bariatric surgery.
- Trial name
- NCT07662538
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obesity, Adolescent
Turnip Consumption and Qigong Exercise Program on Weight Loss
Obesity and weight-related issues are prevalent concerns affecting individuals worldwide, with particular significance among the younger demographic, such as female students.
- Trial name
- NCT06698835
- Testing
- Turnip Consumption
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Obesity
Internet Obesity Treatment Enhanced With Motivational Interviewing
Internet-based weight control programs have been shown effective in producing weight loss, but in-person delivery of behavioral weight control produces significantly greater weight loss than on-line delivery of the same program.
- Trial name
- iReach2 (NCT01232699)
- Testing
- Internet Obesity Treatment, Internet Obesity Treatment with MI, Contingent MI
- Where
- 2 sites in United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- University of Vermont